A5060260027- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- AI in cancer detection
- Spectroscopy Techniques in Biomedical and Chemical Research
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Screening and Detection
- SARS-CoV-2 and COVID-19 Research
- Colorectal and Anal Carcinomas
- Molecular Biology Techniques and Applications
- Cardiac tumors and thrombi
- Asthma and respiratory diseases
- Vasculitis and related conditions
- COVID-19 Clinical Research Studies
- Vascular Tumors and Angiosarcomas
- Digital Imaging for Blood Diseases
- Lung Cancer Diagnosis and Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Colorectal Cancer Surgical Treatments
- Diabetes Treatment and Management
- Gastric Cancer Management and Outcomes
- Image Processing Techniques and Applications
- Renal Diseases and Glomerulopathies
- Cell Image Analysis Techniques
- Colorectal Cancer Treatments and Studies
- T-cell and B-cell Immunology
Asan Medical Center
2020-2024
Ulsan College
2020-2024
University of Ulsan
2020-2024
The quest to reduce kidney transplant rejection has emphasized the urgent requirement for development of non-invasive, precise diagnostic technologies. These technologies aim detect antibody-mediated (ABMR) and T-cell-mediated (TCMR), which are asymptomatic pose a risk potential damage. protocols managing caused by ABMR TCMR differ, diagnosis traditionally relied on invasive biopsy procedures. Therefore, convergence system using nano-sensing chip, Raman spectroscopy, AI technology was...
Abstract There has been a persistent demand for an innovative modality in real-time histologic imaging, distinct from the conventional frozen section technique. We developed artificial intelligence-driven evaluation model gastric cancer tissue using confocal laser endomicroscopic system. The remarkable performance of suggests its potential utilization as standalone instantaneous assessment and complementary tool pathologists’ interpretation.
Hematoxylin and eosin (H&E) staining has been widely used as a fundamental essential tool for diagnosing diseases understanding biological phenomena by observing cellular arrangements tissue morphological changes. However, conventional methods commonly involve solution-based, complex, multistep processes that are susceptible to user-handling errors. Moreover, inconsistent results owing artifacts pose real challenges accurate diagnosis. This study introduces solution-free H&E method based on...
Background/Aim: The need for instant histological evaluation of fresh tissue, especially in cancer treatment, remains paramount. conventional frozen section technique has inherent limitations, prompting the exploration alternative methods. A recently developed confocal laser endomicroscopic system provides real-time imaging tissue without glass slide preparation. Herein, we evaluated its applicability histologic gastric tissues. Materials and Methods: (CLES) with a Lissajous pattern...
Primary cardiac sarcomas are rare and their clinicopathologic features heterogeneous. Among them, particularly intimal sarcoma is a diagnostic challenge due to nonspecific histologic features. Recently, MDM2 amplification reported be characteristic genetic event in the sarcoma. In this study, we aimed identify types incidence of primary that occurred over 25 years tertiary medical institutions, find clinicopatholgical significance through reclassification diagnoses using additional...
Background Pathologic diagnosis of antibody-mediated rejection (ABMR) in ABO-incompatible (ABOi) transplantation patients is often challenging because without ABMR are frequently immunopositive for C4d. The aim this study was to determine whether C4d positivity with microvascular inflammation (MVI), the absence any detectable donor-specific antibodies (DSAs) ABOi patients, could be considered as ABMR. Methods A retrospective 214 for-cause biopsies from 126 kidney performed. Patients MVI...
The impact of the coronavirus disease 2019 (COVID-19) vaccination on humoral and cellular immunity in transplant recipients remains unknown. We report case a 78-year-old kidney recipient who experienced acute T cell-mediated rejection after receiving second dose BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech). She had no history throughout 13 years deceased donor transplantation. Fifteen days vaccine, visited our center with mild headache fever. Her serum creatinine level increased from...
Pellino-1 plays a crucial role in cellular proliferation and regulates inflammatory processes. This study investigated expression patterns their relationship with CD4+ T-cell subsets psoriasis patients. Group 1 comprised primarily biopsied lesions from 378 patients, multiplex-immunostained for Pellino-1, CD4 representative T helper (Th) cells (T-bet [Th1], GATA3 [Th2], RORγt [Th17] regulatory cell [FoxP3] markers). Ki-67 labeling was evaluated the epidermis. 2 43 Pellino-1-positive cases...