A5038055393- Plant Parasitism and Resistance
- Plant and animal studies
- Plant Molecular Biology Research
- Urban and Freight Transport Logistics
- Economics of Agriculture and Food Markets
- Transport and Economic Policies
- Allelopathy and phytotoxic interactions
- Soil Mechanics and Vehicle Dynamics
- Agricultural Economics and Policy
- Cooperative Studies and Economics
- Agriculture and Rural Development Research
- Plant Diversity and Evolution
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Photosynthetic Processes and Mechanisms
- Ferroptosis and cancer prognosis
- Gene expression and cancer classification
- Global trade and economics
- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Plant Stress Responses and Tolerance
- Seed Germination and Physiology
- Biofuel production and bioconversion
- Law, logistics, and international trade
- Agricultural Engineering and Mechanization
University of California, Riverside
2017-2025
University of Manitoba
2018-2023
St. Boniface Hospital
2018-2021
Agri Food and Biosciences Institute
2020
University of Georgia
2012-2019
The University of Western Australia
2008-2011
ARC Centre of Excellence in Plant Energy Biology
2008-2011
Australian Research Council
2010-2011
Western Australian Marine Science Institution
2011
University of Wisconsin–Madison
2007-2009
Karrikins are butenolides derived from burnt vegetation that stimulate seed germination and enhance seedling responses to light. Strigolactones endogenous butenolide hormones regulate shoot root architecture, the branching of arbuscular mycorrhizal fungi. Thus, karrikins strigolactones structurally similar but physiologically distinct plant growth regulators. In Arabidopsis thaliana, both classes require F-box protein MAX2, it remains unclear how discrete achieved. rice, DWARF14 is required...
Smoke is an important abiotic cue for plant regeneration in postfire landscapes. Karrikins are a class of compounds discovered smoke that promote seed germination and influence early development many plants by unknown mechanism. A genetic screen karrikin-insensitive mutants Arabidopsis thaliana revealed karrikin signaling requires the F-box protein MAX2, which also mediates responses to structurally-related strigolactone family phytohormones. synthetic GR24 trigger similar effects on...
The plant hormones strigolactones and smoke-derived karrikins are butenolide signals that control distinct aspects of development. Perception both molecules in Arabidopsis thaliana requires the F-box protein MORE AXILLARY GROWTH2 (MAX2). Recent studies suggest homologous SUPPRESSOR OF MAX2 1 (SMAX1) DWARF53 (D53) rice (Oryza sativa) downstream targets MAX2. Through an extensive analysis loss-of-function mutants, we demonstrate SMAX1-LIKE genes SMXL6, SMXL7, SMXL8 co-orthologs D53 promote...
Discovery of the primary seed germination stimulant in smoke, 3-methyl-2H-furo[2,3-c]pyran-2-one (KAR1), has resulted identification a family structurally related plant growth regulators, karrikins. KAR1 acts as key trigger for many species from fire-prone, Mediterranean climates, but molecular mechanism this response remains unknown. We demonstrate that Arabidopsis (Arabidopsis thaliana), an ephemeral temperate northern hemisphere never, to our knowledge, been reported be responsive fire or...
Obligate parasitic plants in the Orobanchaceae germinate after sensing plant hormones, strigolactones, exuded from host roots. In Arabidopsis thaliana, α/β-hydrolase D14 acts as a strigolactone receptor that controls shoot branching, whereas its ancestral paralog, KAI2, mediates karrikin-specific germination responses. We observed but not D14, is present at higher copy numbers species than nonparasitic relatives. KAI2 paralogs parasites are distributed into three phylogenetic clades. The...
Abiotic chemical signals discovered in smoke that are known as karrikins (KARs) and the endogenous hormone strigolactone (SL) control plant growth through a shared MORE AXILLARY GROWTH2 (MAX2)-dependent pathway. A SL biosynthetic pathway candidate KAR/SL receptors have been characterized, but signaling downstream of MAX2 is poorly defined. screen for genetic suppressors enhanced seed dormancy phenotype max2 Arabidopsis (Arabidopsis thaliana) led to identification suppressor 1 (smax1) mutant....
Karrikins are a class of seed germination stimulants identified in smoke from wildfires. Microarray analysis imbibed Arabidopsis thaliana seeds was performed to identify transcriptional responses KAR 1 before germination. A small set genes that regulated by , even when is prevented the absence gibberellin biosynthesis or light, were identified. Light-induced genes, putative HY5-binding targets, and ABRE-like promoter motifs overrepresented among -up-regulated genes. transiently induced light...
The α/β-hydrolases KAI2 and D14 are paralogous receptors for karrikins strigolactones, two classes of plant growth regulators with butenolide moieties. act in parallel signaling pathways that share a requirement the F-box protein MAX2, but produce distinct responses by regulating different members SMAX1-LIKE/D53 family. kai2 max2 mutants seed germination, seedling growth, leaf shape, petiole orientation phenotypes not found d14 or SL-deficient mutants. This implies recognizes an unknown,...
Drought causes substantial reductions in crop yields worldwide. Therefore, we set out to identify new chemical and genetic factors that regulate drought resistance Arabidopsis thaliana. Karrikins (KARs) are a class of butenolide compounds found smoke promote seed germination, have been reported improve seedling vigor under stressful growth conditions. Here, discovered mutations KARRIKIN INSENSITIVE2 (KAI2), encoding the proposed karrikin receptor, result hypersensitivity water deprivation....
Strigolactones (SLs) are a class of plant hormones that control many aspects growth. The SL signalling mechanism is homologous to karrikins (KARs), smoke-derived compounds stimulate seed germination. In angiosperms, the receptor an α/β-hydrolase known as DWARF14 (D14); its close homologue, KARRIKIN INSENSITIVE2 (KAI2), functions KAR and likely recognizes uncharacterized, endogenous signal ('KL'). Previous phylogenetic analyses have suggested KAI2 lineage ancestral in land plants, canonical...
Karrikins (KARs) are butenolides found in smoke that can influence germination and seedling development of many plants. The KAR signaling mechanism is hypothesized to be very similar the plant hormone strigolactone (SL). Both pathways require F-box protein MORE AXILLARY GROWTH2 (MAX2), other core components have shared ancestry. Putatively, activates receptor KARRIKIN INSENSITIVE2 (KAI2), triggering its association with E3 ubiquitin ligase complex SCFMAX2 downstream targets SUPPRESSOR OF...
Myocardial ischemia-reperfusion (I/R) injury increases the generation of oxidized phosphatidylcholines (OxPCs), which results in cell death. However, mechanism by OxPCs mediate death and cardiac dysfunction is largely unknown. The aim this study was to determine mechanisms OxPC triggers cardiomyocyte during reperfusion injury. Adult rat ventricular cardiomyocytes were treated with increasing concentrations various purified fragmented OxPCs. Cardiomyocyte viability, bioenergetic response,...
The effects of the phytohormone strigolactone (SL) and smoke-derived karrikins (KARs) on plants are generally distinct, despite fact that they perceived through very similar mechanisms. homologous receptors DWARF14 (D14) KARRIKIN-INSENSITIVE2 (KAI2), together with F-box protein MORE AXILLARY GROWTH2 (MAX2), mediate SL KAR responses, respectively, by targeting different SMAX1-LIKE (SMXL) family proteins for degradation. These mechanisms putatively well-insulated, D14-MAX2 SMXL6, SMXL7, SMXL8...
Hormone-activated proteolysis is a recurring theme of plant hormone signaling mechanisms. In strigolactone signaling, the enzyme receptor DWARF14 (D14) and an F-box protein, MORE AXILLARY GROWTH2 (MAX2), mark SUPPRESSOR OF MAX2 1-LIKE (SMXL) family proteins SMXL6, SMXL7, SMXL8 for rapid degradation. Removal these transcriptional corepressors initiates downstream growth responses. The homologous SMXL3, SMXL4, SMXL5, however, are resistant to MAX2-mediated We discovered that smxl4 smxl5 mutant...
Strigolactones (SLs) are methylbutenolide molecules derived from β-carotene through an intermediate carlactonoic acid (CLA). Canonical SLs act as signals to microbes and plants, whereas noncanonical primarily plant hormones. The cytochrome P450 CYP722C catalyzes a critical step, converting CLA canonical in most angiosperms. Using synthetic biology, we investigated the function of CYP722A , evolutionary predecessor . converts into 16-hydroxy-CLA (16-OH-CLA), SL detected exclusively shoots...