A5070099567- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Nerve injury and regeneration
- Neurological Disease Mechanisms and Treatments
- Toxin Mechanisms and Immunotoxins
- Asthma and respiratory diseases
- Blood Pressure and Hypertension Studies
- Medicinal Plants and Neuroprotection
- Natural product bioactivities and synthesis
- Ginkgo biloba and Cashew Applications
- Allergic Rhinitis and Sensitization
- Natural Compounds in Disease Treatment
- Parkinson's Disease Mechanisms and Treatments
- Ginseng Biological Effects and Applications
- Neurological diseases and metabolism
- Flavonoids in Medical Research
- Neuroscience and Neuropharmacology Research
- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- Heart Rate Variability and Autonomic Control
- Clinical Nutrition and Gastroenterology
- Biochemical effects in animals
- Hormonal Regulation and Hypertension
- Cardiovascular Health and Risk Factors
Fujian Medical University
2016-2024
First Affiliated Hospital of Fujian Medical University
2016-2024
Fujian University of Traditional Chinese Medicine
2013-2017
Summary Aim Nerve growth factor ( NGF ) regulates neuronal survival and differentiation by activating extracellular signal‐regulated‐kinases ERK 1/2 phosphoinositide‐3‐kinase PI 3K)/Akt pathways in two distinct processes: latency process neurite extension process. This study was designed to investigate whether botanical drug C‐glucosylated isoflavone puerarin coordinates with regulate neuritogenesis via 3K/Akt Methods We investigated the neuroprotective neurotrophic activities of MPTP...
Background Patients with somatization symptoms are at elevated risk of depression, yet underdiagnosis persists due to cultural tendencies (e.g., in China) express psychological distress via physical complaints. Existing predictive models lack integration sociocultural and physiological factors, particularly non-Western populations. Objective To develop a culturally tailored risk-prediction model for depression patients symptoms, emphasizing early identification personalized intervention....
Wistar rats were intragastrically perfused with Chinese medicines used for tonifying the kidney. These included 0.180 g/mL of Herba Epimedii (Epimedium), Semen Cuscutae (Dodder Seed), or Cistanches (Desertliving Cistanche), 0.04 mg/mL monoamine oxidase-B inhibitor selegiline, distilled water 14 consecutive days to prepare drug-containing serum blank serum. MES23.5 cells in logarithmic phase cultured media supplemented 15% 24 hours, followed by incubation culture solution containing 100...
Cerebral hypoperfusion is a common feature of vascular dementia and has recently been recognized to contribute the progression cognitive decline. The present study aimed investigate effects Bushen Huoxue decoction (BHD), two‑herb Chinese Medicine, on impairment in rat model cerebral induced by permanent occlusion bilateral carotid arteries (2VO). results demonstrated that BHD significantly attenuated learning spatial memory deficits Morris water maze test dose‑dependent manner. Transmission...
Progressive degeneration of dopaminergic neurons in the substantia nigra (SN) is implicated Parkinson’s disease (PD). The efficacy these currently used drugs limited while traditional Chinese medicine (TCM) has been management neurodegenerative diseases for many years. This study was designed to evaluate effect a modified herbal decoction, Cong Rong Jing (CRJ), on cell survival and apoptosis 1-methyl-4-phenylpyridinium- (MPP + -) treated MES23.5 cells. CRJ prepared as decoction from three...
Oxidative damage plays a critical role in the etiology of neurodegenerative disorders including Parkinson’s disease (PD). In our study, an ancient Chinese kidney-tonifying formula, which consists Cistanche , Epimedii, and Polygonatum cirrhifolium was investigated to protect MES23.5 dopaminergic neurons against hydrogen peroxide- (H 2 O -) induced oxidative damage. The effects H on cells protective KTF stress were evaluated using MTT assay, transmission electron microscopy (TEM),...
Objective Cardiac autonomic function predicts cardiovascular disease risk. The aim of this study was to investigate the relationship between sensitization dust allergens and cardiac dysfunction in patients with chronic obstructive pulmonary (COPD), provide new ideas for prevention complications these patients. Methods Immunoassays cats/dogs, cockroaches mites were performed 840 COPD. Indicators heart rate variability used assess function, including standard deviation normal-to-normal...
Objective To investigate the correlation between blood pressure rhythm and left ventricular structure function in elderly hypertensive patients. Methods A total of 147 patients with high First Hospital Longyan Affiliated to Fujian Medical University were selected.All received 24h ambulatory examination.According pressure, divided into dipper group, the-non type group anti-dipper group.All examined by echocardiography. Results According results dynamic accounted for 11.56%(17...