Kaiwen Zhou

ORCID: 0000-0001-9804-2783
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Angiogenesis and VEGF in Cancer
  • Axon Guidance and Neuronal Signaling
  • Proteoglycans and glycosaminoglycans research
  • Endometrial and Cervical Cancer Treatments
  • Advanced Radiotherapy Techniques
  • Cancer-related molecular mechanisms research
  • Seaweed-derived Bioactive Compounds
  • Phagocytosis and Immune Regulation
  • Immune cells in cancer
  • Ferroptosis and cancer prognosis
  • Autophagy in Disease and Therapy
  • Organoselenium and organotellurium chemistry
  • Semiconductor materials and interfaces
  • Folate and B Vitamins Research
  • Corneal Surgery and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Epigenetics and DNA Methylation
  • Mycobacterium research and diagnosis
  • Management of metastatic bone disease
  • Selenium in Biological Systems
  • MRI in cancer diagnosis
  • Advancements in Battery Materials
  • Radiation Therapy and Dosimetry
  • Chronic Lymphocytic Leukemia Research
  • Biochemical and Molecular Research

Shandong First Medical University
2024-2025

Shandong Tumor Hospital
2025

Academy of Medical Sciences
2024

The First Affiliated Hospital, Sun Yat-sen University
2024

Sun Yat-sen University
2024

Fifth Hospital In Wuhan
2021

Wuhan University
2021

Nanchang University
2018-2020

Inflammatory breast cancer (IBC) is a highly aggressive subtype of characterized by rapidly arising diffuse erythema and edema. Genomic studies have not identified consistent alterations mechanisms that differentiate IBC from non-IBC tumors, suggesting the microenvironment could be potential driver phenotypes. Here, using single-cell RNA sequencing, multiplex staining, serum analysis in patients with IBC, we enrichment subgroup luminal progenitor (LP) cells containing high expression...

10.1158/0008-5472.can-23-2640 article EN cc-by-nc-nd Cancer Research 2024-03-20

Elevation of blood homocysteine (Hcy) level (hyperhomocysteinemia) is a risk factor for cardiovascular disorders and closely associated with endothelial dysfunction. The present study aims to investigate the protective effect underlying mechanism nanoscale selenium (Nano-Se) in Hcy-mediated vascular cell dysfunction vitro vivo.By incubating cells exogenous Hcy generating hyperhomocysteinemic rat model, effects Nano-Se on hyperhomocysteinemia-mediated its essential mechanisms were...

10.2147/ijn.s255392 article EN cc-by-nc International Journal of Nanomedicine 2020-06-01

Bladder volume variations during radiotherapy can significantly influence dose distribution to both target volumes and surrounding organs-at-risk (OARs). This study aims assess the dosimetric impact of variable bladder on clinical (CTV) OARs in cervical cancer patients undergoing MR-guided radiotherapy. A total 27 were included this study: 12 received radical radiotherapy, 15 underwent postoperative All treated with Elekta Unity MR-linac system. The requirement was 95–100% prescribed PTV(45...

10.1186/s12885-025-13442-3 article EN cc-by-nc-nd BMC Cancer 2025-02-21

Background: The bone marrow microenvironment constitutes a sanctuary for leukemia cells. Recent evidence indicates that environment-mediated drug resistance arises from reciprocal influence between tumor cells and the surrounding stroma. present study aimed to investigate effect of chronic lymphocytic (CLL) on metabolism stroma, determine role this metabolic change in stroma vorinostat CLL cells, thus assess novel strategy target achieve maximum therapeutic vorinostat. Methods: To evaluate...

10.2147/ott.s170392 article EN OncoTargets and Therapy 2018-08-01

// Xiaoman Chen 1 , Yulu Shi 2 Kaiwen Zhou Sijie Yu Wei Cai 3 and Muying Ying Department of Molecular Biology Biochemistry, Basic Medical College Nanchang University, Nanchang, PR China Queen Mary School Genetics Cell Biology, Correspondence to: Ying, email: yingmuying@ncu.edu.cn Keywords: chemotherapeutic resistance; lncRNA; citespace; bibliometric analysis Received: February 10, 2019     Accepted: May 02, Published: 14, 2019 ABSTRACT The global outputs annual...

10.18632/oncotarget.26938 article EN Oncotarget 2019-05-14

<div>Abstract<p>Inflammatory breast cancer (IBC) is a highly aggressive subtype of characterized by rapidly arising diffuse erythema and edema. Genomic studies have not identified consistent alterations mechanisms that differentiate IBC from non-IBC tumors, suggesting the microenvironment could be potential driver phenotypes. Here, using single-cell RNA sequencing, multiplex staining, serum analysis in patients with IBC, we enrichment subgroup luminal progenitor (LP) cells...

10.1158/0008-5472.c.7267955.v1 preprint EN 2024-06-04

<div>Abstract<p>Inflammatory breast cancer (IBC) is a highly aggressive subtype of characterized by rapidly arising diffuse erythema and edema. Genomic studies have not identified consistent alterations mechanisms that differentiate IBC from non-IBC tumors, suggesting the microenvironment could be potential driver phenotypes. Here, using single-cell RNA sequencing, multiplex staining, serum analysis in patients with IBC, we enrichment subgroup luminal progenitor (LP) cells...

10.1158/0008-5472.c.7267955 preprint EN 2024-06-04

<title>Abstract</title> Purpose This study aims to assess the dosimetric impact of variable bladder volume on CTV and OAR in cervical cancer patients undergoing radiotherapy. Method A total 27 were included this study: 12 received radical radiotherapy, 15 underwent postoperative All treated with Elekta Unity MR-linac system. The dose requirement was 95–100% prescribed PTV(45 Gy/25 sessions/5 weeks). Daily images acquired at time treatment using MR-linac. For study, MR from first three...

10.21203/rs.3.rs-4818648/v1 preprint EN Research Square (Research Square) 2024-09-08

Radiation therapy plays a significant role in the treatment of cervical cancer. Additionally, more adaptive workflows using ATP are being implemented daily radiotherapy our organization. Herein, we aimed to investigate dosimetric differences between online and offline ATS plans for magnetic resonance (MR)-guided patients with cancer determine modalities that address clinical requirements. In total, 25 were enrolled this study, 13 radical group 12 post-operative group. We target volume (CTV)...

10.36922/arnm.4919 article EN cc-by Deleted Journal 2024-12-31

Glaucoma is a leading cause of vision loss mainly due to retinal ganglion cells (RGC) loss. MicroRNAs (miRNAs) are highlighted as potential biomarkers in diseases. This study aims investigate the role miR-43 and BMSCs RGC apoptosis glaucoma.RGCs were transfected with inhibitors mimics, then co-cultured BMSCs. RT-qPCR analysis was conducted determine expression, whilst Western blot, flow cytometry carried out assess inflammation. The interaction between BDNF, neurotrophic factor, detected by...

10.1166/jbt.2021.2850 article EN Journal of Biomaterials and Tissue Engineering 2021-08-25
Coming Soon ...