A5044933362- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Stroke Rehabilitation and Recovery
- History of Medical Practice
- Infectious Encephalopathies and Encephalitis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Valve Diseases and Treatments
- Pharmacological Effects and Toxicity Studies
- Mitochondrial Function and Pathology
- Cerebrovascular and Carotid Artery Diseases
- Cerebrospinal fluid and hydrocephalus
- Craniofacial Disorders and Treatments
- Diversity and Career in Medicine
- Intracranial Aneurysms: Treatment and Complications
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Anatomy and Medical Technology
- Healthcare Systems and Challenges
- Bacterial Infections and Vaccines
- Healthcare Operations and Scheduling Optimization
- Drug Transport and Resistance Mechanisms
- Aortic Disease and Treatment Approaches
- Cerebral Palsy and Movement Disorders
Universidad Autónoma de Centro América
2022-2025
Yale University
2022-2025
University of Wisconsin–Madison
2024
Southern Illinois University Carbondale
2024
The objective of this study was to investigate inflammation using cerebrospinal fluid (CSF) and serum cytokines/chemokines in patients with new-onset refractory status epilepticus (NORSE) better understand the pathophysiology NORSE its consequences.Patients (n = 61, including n 51 cryptogenic), subtype prior fever known as febrile infection-related epilepsy syndrome (FIRES), were compared other (RSE; 37), control without SE 52). We measured 12 or CSF samples multiplexed fluorescent...
Approximately 30% of critically ill patients have seizures, and more than half these seizures do not an overt clinical correlate. EEG is needed to avoid missing prevent overtreatment with antiseizure medications. Conventional-EEG (cEEG) resources are logistically constrained unable meet their growing demand for seizure detection even in highly developed centers. Brief screening the validated 2HELPS2B algorithm was proposed as a method triage cEEG resources, but it hampered by requirements,...
Background: Primitive arteries are persistent fetal anastomoses between the carotid and vertebral-basilar circulation. They trigeminal, otic, hypoglossal, proatlantal intersegmental arteries. emerge at 4- to 5-mm embryonic stage, persist for approximately 1 week, regress roughly rate which posterior communicating vertebral develop. Although rare, they can birth. Their incidence is inversely related period in appear.
Abstract New onset refractory status epilepticus (NORSE), including its subtype with a preceding febrile illness known as infection‐related epilepsy syndrome (FIRES), is one of the most severe forms epilepticus. The exact causes NORSE are currently unknown, and there so far no disease‐specific therapy. Identifying underlying pathophysiology discovering specific biomarkers, whether immunologic, infectious, genetic, or other, may help physicians in management patients NORSE. A broad spectrum...
The etiology of new-onset refractory status epilepticus (NORSE), including its subtype with prior fever known as FIRES (febrile infection-related epilepsy syndrome), remains uncertain. Several arguments suggest that NORSE is a disorder immunity, likely post-infectious. Consequently, seasonal occurrence might be anticipated. Herein we investigated if seasonality notable factor regarding presentation. We combined four different data sets total 342 cases, all from the northern hemisphere, and...
The history of Colombian neurosurgery is a collective legacy neurosurgeon-scientists, scholars, teachers, innovators, and researchers. Anchored in the country's foundational values self-determination adaptability, these pioneers emerged from Spanish colonial medical tradition forged surgical alliances abroad. From time independence until end World War I, exchanges with French produced an emphasis on anatomical systematic approaches to emerging field neurosurgery. onset American neurosurgical...
Abstract Background: Electroencephalography (EEG) is needed to diagnose nonconvulsive seizures (NCS). Prolonged NCSs are associated with neuronal injuries and deleterious clinical outcomes. However, it uncertain whether the rapid identification of these using point-of-care EEG (POC-EEG) can have a positive impact on Methods: In retrospective cohort sub-analysis recently completed multicenter SAFER-EEG trial, we compared intensive care unit length stay (ICU LOS), poor functional outcome...
The evolution of neurosurgical approaches to spasticity spans centuries, marked by key milestones and innovative practitioners. Probable ancient descriptions spasmodic conditions were first classified as in the 19th century through interventions Dr. William John Little on patients with cerebral palsy. late witnessed pioneering efforts surgeons such Charles Loomis Dana, who explored neurotomies, Sherrington, proposed dorsal rhizotomy address spasticity. Dorsal rose prominence under expertise...
<h3>Objective:</h3> To investigate inflammation using cerebrospinal fluid (CSF) and serum cytokines/chemokines in patients with New-Onset Refractory Status Epilepticus. <h3>Background:</h3> Patients Epilepticus without explanation after initial evaluation (NORSE) often haven poor outcomes. Understanding the pathophysiological mechanisms underlying NORSE its long-term consequences is crucial to improve management prevent secondary neuronal injury. Several arguments suggest a disorder of...
Ernesto Bustamante Zuleta (1922-2021) was an impactful Colombian neurosurgeon whose legacy is inextricably linked with the development of neurosurgery specialty in Colombia. His detail-oriented approach to treatment complemented his reputation for mastery neurosciences. Never simply confined operating theater, this calm and considerate physician felt compelled teach during entire career. The result teaching made a lasting imprint on generation neurosurgeons who subsequently established high...
Incan trepanations have made headlines about high survival rates compared to American civil war craniotomies, based on research such as the one presented by Kushner, Verano et al. at 2017 AAN annual meeting and later published in World of Neurosurgery 2018. The objective is take these findings step further comparing those with contemporary procedures understand where data aligns possible significance results.