A5049455607- Traditional and Medicinal Uses of Annonaceae
- Moringa oleifera research and applications
- Natural Antidiabetic Agents Studies
- African Botany and Ecology Studies
- Ethnobotanical and Medicinal Plants Studies
- Hemoglobinopathies and Related Disorders
- Essential Oils and Antimicrobial Activity
- Microbial Metabolites in Food Biotechnology
- Recycling and Waste Management Techniques
- Nigella sativa pharmacological applications
- Phytochemistry and Bioactive Compounds
- Pregnancy and preeclampsia studies
- Parasites and Host Interactions
- Iron Metabolism and Disorders
- Folate and B Vitamins Research
- Food Chemistry and Fat Analysis
- Cocoa and Sweet Potato Agronomy
- Food Industry and Aquatic Biology
- Seed and Plant Biochemistry
- Autopsy Techniques and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Proteins in Food Systems
- Nanoparticles: synthesis and applications
- Phytochemical compounds biological activities
- Child Nutrition and Water Access
Central Michigan University
2022-2025
University of Health Sciences
2024
University of Health Science
2024
Nnamdi Azikiwe University
2024
University of Benin
2010-2023
University of Science and Technology of Benin
2017-2023
Sokoto State University
2023
Kingsley House
2017
University of Nigeria Teaching Hospital
2013-2016
West African College of Physicians
2010
Abstract Numerous bioactive compounds and phytochemicals have been reported to be present Annona muricata (Soursop). Some of these chemical linked the ethnomedicinal properties plant its antioxidant properties. The aim this study was assess proximate composition, phytochemical constituents in vitro A. using standard biochemical procedures. defatted crude methanolic extracts different parts were used for estimation composition screening. also fractionated solvent–solvent partitioning....
Annona muricata has been attributed with numerous health benefits – including anticancer properties. The aim of this study was to carry out investigations fractions muricata, by isolating a key compound and assessing antioxidant properties were assessed using cell lines, the potent subjected isolation procedures. isolated examined standard spectroscopies further assayed for viability most revealed that ethyl acetate fruit (EAF, 10.62%) leaf (EAL, 10.83%) had highest abilities, followed...
Lead poisoning poses one of the major health challenges affecting all organ systems but mostly nervous, renal, haematopoietic, liver and cardiovascular systems.This study investigated effect milk supplementation on markers hepatic function hematological parameters lead acetate exposed albino rats.Twenty male rats were randomized into four groups five each. Normal control received feed water only. group (Pb) 80mg/kg body weight acetate. Standard (Pb+Vit C) was given daily plus 100mg/kg...
Annona muricata has been used in folklore the management of diabetes. A major strategy decreasing postprandial hyperglycemia diabetes involves inhibition carbohydrate-hydrolyzing enzymes - α-amylase and α-glucosidase. Thus, this study evaluated vivo vitro inhibitory potentials different parts (fruit-pulp, leaf, stem-bark root-bark) muricata. total 120 Wistar rats were treated with methanol extracts for 28 days after which blood tissue samples collected assay. In properties methanol, ethyl...
Mycolic acids are long-chain, α-branched, β-hydroxylated fatty acid lipids that populate the outer mycomembrane of mycobacteria, including pathogen Mycobacterium tuberculosis. predominantly occur in form glycolipids, but non-glycosylated free mycolic (fMA), which generated during remodeling, major constituents M. tuberculosis biofilm extracellular matrix and promote host immune evasion infection. However, our understanding these processes is nascent, there limited information about...
Background A wide array of ethnomedicinal values have been attributed to the different parts Annona muricata, and indigenous communities in Nigeria, Africa, South America extensively use this plant augment conventional drugs.Aim The beneficial effects A. muricata on hematological profile also widely reported research sought validate these claims.Design Adult albino Wistar rats were used study. Methanolic extracts various used, with which we determined 50% lethal dose (LD50) acute toxicity...
Purpose: This study investigated mortality rate, early CD4 responses, pattern of ARVs substitutions and medication adherence HIV-infected patients on first-line triple combination antiretroviral therapy (ART) in Central Hospital, Benin City, Nigeria. Methods: A retrospective assessment 196 ART regimens was performed following 18 months therapy. Medication a 69- patient follow-up target group based study-specific questionnaire. Paired sample t-test simple linear correlation were used to test...
ABSTRACT The glycemic index (GI) and load (GL) of processed brown cowpea (Vigna unguiculata) were determined. whole seeds dehulled, ground into a paste steamed ("moin-moin" MM) or fried ("Akara" FB). Proximate analyses done to determine the quantity containing 50 g available carbohydrate. Forty healthy volunteers used for this study. test groups consumed while glucose was administered control group. blood response at 0, 30, 60,120 180 min assessed each individual different groups. GI values...
Introduction: Previous studies had enlisted renal medullary carcinoma (RMC) as the seventh nephropathy in sickle cell disease (SCD). Clinical experience has contradicted this claim and study is targeted at refuting or supporting assumption.Objective: To estimate prevalence of RMC describe other complications SCD.Materials methods: 14 physicians (haematologists urologists) 11 tertiary institutions across country were collated from patients' case notes hospital SCD registers.Results: Of 3,596...
Most people on folic acid to boost erythropoiesis and prophylactic antimicrobials, the standard management of steady state sickle cell disease (SCD), have unacceptable numbers crises. The objective this study was evaluate effects adding multimodal therapy with potassium thiocyanate omega-3 fatty acids SCD. Pre- post-treatment crises other indices were compared in 16 HbSS individuals paludrine after 12 months eicosapentaenoic 15 mg/kg/day, docosahexaenoic 10 1-2 mL/day, each milliliter which...
To assess the prevalence and associations of symptomatic renal papillary necrosis (RPN) in sickle cell anemia patients.The case notes homozygous hemoglobin (Hb) S patients diagnosed with RPN were retrospectively assessed. Diagnosis was based on microscopic hematuria positive ultrasound findings. Their steady state diastolic blood pressure, Hb, leukocyte count, platelet serum direct bilirubin, aspartate transaminase, obtained by automated analyzers. These evaluated for any relationship...
Pregnancy has been associated with changes in physiologic and metabolic functions accompanied by a high demand elevated requirements for tissue oxygen eventual increase oxidative pressure on the antioxidant defence system of body. Thus, it was based this premise that some markers pro-oxidant- status pregnancy compared non-pregnant state were assessed including, marker lipid peroxidation (malondialdehyde, MDA), superoxide dismutase (SOD), catalase (CAT) glutathione peroxidise (GPx). A total...
Annona muricata (Soursop) has attracted attention due to its content of annonaceous acetogenins, a large family naturally occurring polyketides isolated from various species the genus Annonaceae. The ethyl acetate fraction was subjected standard isolation protocol-gradient and isocratic silica gel column chromatography- obtain three waxy whitish amorphous compounds, 002/A1, 002/A2 002/C. structure compound 200/A2 elucidated using 1H-NMR spectroscopy, infrared spectroscopy electron impact...
Type 1 diabetes mellitus is an autoimmune disorder characterized by the destruction of pancreatic beta cells, leading to impaired insulin production and regulation. Recent research has shown that medicinal plants with antioxidant anti-inflammatory properties hold promise as potential therapeutic agents for managing complications disease. The aim this study investigate anti-diabetic, antioxidant, effect ethyl acetate extract Annona muricata leaves in streptozotocin (STZ)-induced Wistar rats....
Properties a given waste is essential for rationale comprehension of plausible way(s) its remediation. In the present study, POME from oil milling centre at Anambra state showed high heterotrophic activity microorganisms. Total viable counts organisms isolated water were 5.4 x 103 CFU/ml and 4.4 day 0 7 incubation respectively. These observations significant variation control experiment these recorded days incubations which shows total cell (TVC) 4.6 2.9 104 coliform (TCC) dairy 1.3 1.8...
Medicinal herbs have been extensively utilized in the remediation of various health conditions. Dialium guineense fruit pulp, also well known as Velvet Tamarind is widely consumed West Africa for its dietary and medicinal properties. The study aims to analyze phytochemical constituents, vitamin content vitro antioxidant effect pulp (DGFP). vitamins (C, E, B1-12) composition, activity were examined utilizing standardized analytical methods. qualitative quantitative screening was carried out;...