A5103058595- Advanced Memory and Neural Computing
- Semiconductor materials and devices
- Ferroelectric and Negative Capacitance Devices
- Transition Metal Oxide Nanomaterials
- Vehicular Ad Hoc Networks (VANETs)
- Phase-change materials and chalcogenides
- Osteoarthritis Treatment and Mechanisms
- Machine Learning and ELM
- Mobile Ad Hoc Networks
- Bioinformatics and Genomic Networks
- Advanced Data Storage Technologies
- Traffic control and management
- Advanced MIMO Systems Optimization
- Cooperative Communication and Network Coding
- Transportation and Mobility Innovations
- Gene expression and cancer classification
- Neuroscience and Neural Engineering
- Electronic and Structural Properties of Oxides
- Opportunistic and Delay-Tolerant Networks
- Energy Efficient Wireless Sensor Networks
- IoT-based Smart Home Systems
- Cognitive Radio Networks and Spectrum Sensing
- Fibroblast Growth Factor Research
- S100 Proteins and Annexins
- Gas Sensing Nanomaterials and Sensors
German Cancer Research Center
2023-2024
Macronix International (Taiwan)
2011-2024
Southern Medical University
2024
Nanfang Hospital
2024
Heidelberg University
2023-2024
Epigenomics (Germany)
2023-2024
National Taiwan University
1993-2023
Kaohsiung Chang Gung Memorial Hospital
2019-2023
Chang Gung University
2019-2023
Feng Chia University
2021-2023
To successfully deploy femtocells overlaying the Macrocell as a two-tier that had been shown greatly benefiting communications quality in various manners, it requires to mitigate cross-tier interference between and femtocells, intra-tier among well provide Quality-of-Service (QoS) guarantees. Existing solutions therefore assign orthogonal radio resources frequency spatial domains each network, however, infeasible for dense deployments. It is also difficult apply centralized resource...
AT-rich interaction domain protein 1A (ARID1A), a SWI/SNF chromatin remodeling complex subunit, is frequently mutated across various cancer entities. Loss of ARID1A leads to DNA repair defects. Here, we show that plays epigenetic roles promote both double-strand breaks (DSBs) pathways, non-homologous end-joining (NHEJ) and homologous recombination (HR). accumulated at DSBs after damage regulates loops formation by recruiting RAD21 CTCF DSBs. Simultaneously, facilitates transcription...
Resistive random access memory (ReRAM) is often considered as a strong candidate for storing the weights in non-von Neumann neuromorphic computing systems. This paper studies how nonideal characteristics, which include programing error, read fluctuation, and retention, affect inference accuracy of analog ReRAM neural networks by incorporating characteristics extracted from 1-Mb into simulated inference-only network. also shows that different layer network can tolerate amount such imperfects....
A thorough study of the switching mechanism for WO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">X</sub> ReRAM gives clues about how to improve its performance and reliability. Consequently, a 60 nm is achieved with excellent characteristics - 50ns fast switching, 10 <sup xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> cycling endurance, large MLC window, low read disturb >; xmlns:xlink="http://www.w3.org/1999/xlink">9</sup> ,...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder. This study aimed to examine whether miRNA expression abundance in total white blood cells (WBCs) facilitated the identification of ADHD and reflected its response treatment. Furthermore, markers growth human cortical neuronal (HCN-2) was also investigated. Total WBC samples were collected from 145 patients 83 controls, followed by RNA extraction qPCR assays. Subsequently, at endpoint...
40nm WO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">X</sub> ReRAM has several unique characteristics that are very favorable for MLC application. (1) Although the resistance strong temperature dependence (as all ReRAM's) J-V can be accurately described, thus levels easily modeled. (2) The device is immune to over-erase, allow fast programming. (3) programming self-converging Flash memories) and independent of history. Thus an algorithm...
Lin Y‐Y, Tanaka N, Ohkuma S, Iwabuchi Y, Tanne Kamiya T, Kunimatsu R, Huang Y‐C, Yoshioka M, Mitsuyoshi Tanimoto K, E, K. Applying an excessive mechanical stress alters the effect of subchondral osteoblasts on chondrocytes in a co‐culture system. Eur J Oral Sci 2010; 118: 151–158. © 2010 The Authors. Journal compilation Osteoarthritis (OA) sometimes occurs as consequence repeated microtrauma involved parafunction, which may lead to microfracture bone. aim this vitro study was evaluate...
An easy to fabricate, low-cost, multi-layer sidewall WO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">X</sub> ReRAM device is proposed for 3D application. A 2-layer (10nm × 100nm) fabricated and characterized the first time. The WOX grown by conventional RTO process but a special semi-permeable TiN (SP-TiN) developed achieve necessary extrusion-free structure ReRAM. devices show characteristics similar planar devices, reasons layer-to-layer...
Storage class memory (SCM) does not need long data retention (since the are refreshed regularly) but has very stringent requirements on read/write speed and cycling endurance. Even though phase change (PCM) is a leading candidate currently no material can satisfy both endurance requirements. This because although GST-225 fast switching it suffers large volume when melting thus limited Attempts to improve so far must sacrifice speed. work explores new by atomic-level engineering doping GST....
Superficial zone protein (SZP) has been demonstrated to contribute the boundary lubrication in synovial joints. This study was designed clarify modulation of SZP expression by mechanical stress articular chondrocytes. Cyclic tensile strains 7 and 21% cell elongation were applied cultured chondrocytes obtained from porcine mandibular condylar cartilage. The mRNA levels SZP, IL-1 beta, TGF-beta1 examined a quantitative real-time PCR analysis. Protein level Western blotting. significantly...
Recent advances in sequencing technology have opened a new era RNA studies. Novel types of RNAs such as long non-coding (lncRNAs) been discovered by transcriptomic and some lncRNAs found to play essential roles biological processes. However, only limited information is available for Drosophila melanogaster, an important model organism. Therefore, the characterization identification D. melanogaster area research. Moreover, there increasing interest use ChIP-seq data (H3K4me3, H3K36me3 Pol II)...
Pesticide resistance poses many challenges for pest control, particularly destructive pests such as diamondback moths ( Plutella xylostella ). Organophosphates have been used in the field since 1950s, leading to selection resistance-related gene variants and development of new insecticides moth. Identifying actual potential genes involved could offer solutions control. This study established resistant moth strains from two different collections using mevinphos. Two sets transcriptome...
Advances in autonomous vehicular technology facilitate the development of intelligent traffic regulation systems. Such a system aims to configure and regulate mobility patterns enhance in-road transportation safety efficiency. To effectively function, must enable high-rate communications rapid dissemination vehicle-to-vehicle messaging flows. Instead applying classical models capture human driver behaviors, use autonomously controlled driverless vehicles brings up another design...
Autoimmune encephalitis (AE) is a severe neurological disease. The brain of the AE patient attacked by dysregulated immune system, which caused excessive production autoantibodies against neuronal receptors and synaptic proteins. also characterized uncontrolled B lymphocyte infiltration through blood-brain barrier (BBB) layer, investigation underlying mechanism involved in this may facilitate discovery novel therapies for AE. However, few AE-related studies have focused on issue. In study,...
A complementary metal oxide semiconductor (CMOS)-compatible WO x based resistive memory has been developed. The layer is made from rapid thermal oxidation of W plugs. device performs excellent electrical properties. switching speed extremely fast (∼2 ns) and the programming voltage (<1.4 V) low. For single-level cell (SLC) operation, shows a large resistance window, 10 8 -cycle endurance. multi-level (MLC) it demonstrates 2-bit/cell storage with endurance up to 10000 times. (RTO) random...
We propose a novel processing-in-memory (PIM) architecture based on the voltage summation concept to accelerate vector-matrix multiplication for neural network (NN) applications. The core device is formed by adding buried shunt resistor floating gate Flash memory device. NN string constructed same way as in NAND connecting devices series. In perceptron operation weighting factors are stored and sum-of-product readily obtained summing drop of cells each string. energy consumption 128...
Abstract DNA methylation is a widely studied epigenetic mark and powerful biomarker of cell type, age, environmental exposures, disease. Whole-genome sequencing following selective conversion unmethylated cytosines into thymines via bisulfite treatment or enzymatic methods remains the reference method for profiling genome-wide. While numerous software tools facilitate processing reads, comprehensive benchmarking study has been lacking thus far. In this study, we systematically compared...
The behavior of WO X resistive random access memory (ReRAM) is a strong function the top electrode material, which controls conduction mechanism and forming process. When using with low work function, current limited by space charges. On other hand, becomes thermionic emission for devices high electrode. These (thermionic) are also found to have higher initial resistance, reduced current, larger resistance window. Based on these insights considering compatibility complementary...