- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Neonatal and fetal brain pathology
- Online and Blended Learning
- EEG and Brain-Computer Interfaces
- Diet and metabolism studies
- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- Nerve Injury and Rehabilitation
- Neutropenia and Cancer Infections
- Balance, Gait, and Falls Prevention
- Sleep and Wakefulness Research
- Action Observation and Synchronization
- Hemoglobinopathies and Related Disorders
- Nasal Surgery and Airway Studies
- Motor Control and Adaptation
- Pediatric Pain Management Techniques
- Obstructive Sleep Apnea Research
- Colorectal Cancer Screening and Detection
- Brucella: diagnosis, epidemiology, treatment
- Pain Management and Treatment
- Digital Imaging for Blood Diseases
- Clinical Laboratory Practices and Quality Control
- Peripheral Neuropathies and Disorders
Johns Hopkins Medicine
2024-2025
Johns Hopkins University
2024-2025
Children's Healthcare of Atlanta
2019-2024
Aflac (United States)
2022-2024
Sir Charles Gairdner Hospital
2009-2024
Epilepsy Action
2022
Imperial College London
2021-2022
Royal Perth Hospital
2013-2022
The University of Western Australia
2022
New York University
2009-2017
Breast surgery is a common procedure performed in women. Many women who undergo breast suffer from ill-defined pain syndromes. Although there exists few reports on the incidence of post mastectomy pain, are no published chronic after reconstruction. This investigation attempts to characterize four types surgery: (1) mastectomy, (2) with reconstruction, (3) cosmetic augmentation, and (4) reduction. A questionnaire was mailed 479 underwent at University California, San Diego Medical Center...
In multiple sclerosis (MS), microglia and macrophages within the central nervous system (CNS) play an important role in determining balance among demyelination, neurodegeneration, myelin repair. Phagocytic regenerative functions of these CNS innate immune cells support remyelination, whereas chronic maladaptive inflammatory activation promotes lesion expansion disability, particularly progressive forms MS. No currently approved drugs convincingly target CNS, contributing to lack therapies...
Objective. The purpose of this study was to compare prostate cancer incidence and mortality trends between the United States Canada over a period approximately 30 years. Methods. Prostate incident cases were chosen from National Cancer Institute's Surveillance Epidemiology End Results (SEER) Program estimate rates for white males Canadian Registry men. vital statistics data used both countries, age-adjusted age-specific calculated. Joinpoint analysis identify significant changes in time....
Background: Datasets on rare diseases, like pediatric acute myeloid leukemia (AML) and lymphoblastic (ALL), have small sample sizes that hinder machine learning (ML). The objective was to develop an interpretable ML framework elucidate actionable insights from tabular disease datasets. Methods: comprehensive employed optimized data imputation sampling, supervised unsupervised learning, literature-based discovery (LBD). deployed assess treatment-related infection in AML ALL. Results: An...
<h3>Summary</h3> The role of neuroimaging in the assessment a first-ever seizure has not been well-defined, particular utility MRI when CT is normal. results (CT brain, or both) 1,013 adults with unprovoked were correlated clinical features and outcome. Epileptogenic lesions identified 29%. Of patients normal who also had MRI, 12% an epileptogenic lesion on strongest independent predictor which was focal abnormality EEG. Patients higher risk recurrence, including this only evident MRI.
Epilepsy has recently been redefined to include a single unprovoked seizure if the probability of recurrence is ≥60% over following 10 years. This definition based on estimated risk third after two seizures, using lower-limit 95% confidence interval (CI) at 4 years, and does not account for initially high rate first-ever that rapidly falls with increasing duration freedom. We analyzed long-term outcomes seizure, influence freedom likelihood recurrence, their relevance new...
Patients with a first-ever unprovoked seizure commonly have subsequent seizures and identifying predictors of recurrence has important management implications. Both prior brain insult epileptiform abnormalities on electroencephalography (EEG) are established recurrence. Some studies suggest that from sleep higher likelihood However, relatively small numbers inconsistent definitions, more data required.
Background After a first-ever seizure, 6 months of seizure freedom is usually required before returning to driving private motor vehicle, after which the annual risk recurrence has fallen ≤20%. Stricter criteria apply for commercial driver’s licence (CDL) holders, and longer period sufficient be <2% recommended. However, CDL guidelines are based on little data with few studies having long-term follow-up. Methods 1714 patients seizures were prospectively studied. Seizure was evaluated...
Anti-GD2 antibody therapy is a promising experimental treatment that targets gangliosides on disseminated neuroblastoma cells as well normal nervous tissue [1-4]. The infusion of the associated with pain in abdomen, back, and extremities, which appears within 20 minutes after initiation ceases shortly ending infusion. Pain conventionally controlled moderate to large doses morphine. Because nature syndrome resulting from anti-GD2 therapy, we had reason believe small-dose intravenous (IV)...
Abstract Objective To examine the factors and reasons influencing treatment initiation decisions in patients with newly diagnosed epilepsy. Methods We assessed antiseizure medication adults epilepsy seen at first seizure clinics Western Australia between 1999 2016 followed to 2018. Results Of 610 (median age 40 years, 61.0% male), 426 (69.8%) were after two or more seizures 184 (30.2%) a single risk for recurrence. Treatment was commenced 427 (70.0%) diagnosis, 112 (18.4%) during follow‐up,...
Anti-GD2 antibody therapy is a promising experimental treatment that targets gangliosides on disseminated neuroblastoma cells as well normal nervous tissue [1-4]. The infusion of the associated with pain in abdomen, back, and extremities, which appears within 20 minutes after initiation ceases shortly ending infusion. Pain conventionally controlled moderate to large doses morphine. Because nature syndrome resulting from anti-GD2 therapy, we had reason believe small-dose intravenous (IV)...
This study examines how people learn to perform lower limb control in a novel task with hoverboard requiring maintain dynamic balance. We designed an experiment investigate the learning of balance and two strategies: A hip strategy, which mainly uses movements change angle foot, ankle strategy relying more on motion orientation plates controlling motion. Motor was indicated by significant [Formula: see text]% decrease trial completion time (p < 0.001) 24 ± 11% total muscle activation 0.001)....
The low level lasers currently in the market vary wavelength, dosage, and frequency. These devices are used with much different clinical pathology. Most notably, some studies claim that wounds heal faster laser therapy due to fact bacteria commonly found killed by light. Systemic meta-analysis difficulty of comparison numerous research because differences intensities frequencies treatment (LLLT). purpose this study was determine effectiveness LLLT on controlling bacterial growth.
We conducted a retrospective chart review to examine the efficacy of adenotonsillectomy for treatment severe obstructive sleep apnea (OSA) in children. Our study population was made up 85 patients-58 boys and 27 girls, aged 1 17 years (mean: 6.9 ± 4.4)-with OSA who had undergone pre- postoperative attended polysomnography (PSG) over 4-year period. Severe defined as an apnea-hypopnea index (AHI) >10 events per hour sleep. Patients underlying genetic or craniofacial anomaly were excluded. In...