A5019053121- Essential Oils and Antimicrobial Activity
- Traditional and Medicinal Uses of Annonaceae
- Piperaceae Chemical and Biological Studies
- Bioactive Natural Diterpenoids Research
- Phytochemistry and Biological Activities
- Gene expression and cancer classification
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Bioactivity Studies
- Biochemical and Structural Characterization
- Alkaloids: synthesis and pharmacology
- Botany, Ecology, and Taxonomy Studies
- Cell Image Analysis Techniques
- Plant Pathogenic Bacteria Studies
- Antioxidant Activity and Oxidative Stress
- Plant Disease Management Techniques
- Moringa oleifera research and applications
- Natural product bioactivities and synthesis
- Plant Virus Research Studies
- Ethnobotanical and Medicinal Plants Studies
- Venomous Animal Envenomation and Studies
- Botanical Research and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Insect Pest Control Strategies
Universidade do Estado do Amazonas
2018-2024
Escola Superior de Ciências da Saúde
2022
National Institute of Amazonian Research
2020
Understanding the distribution of hundreds thousands plant metabolites across kingdom presents a challenge. To address this, we curated publicly available LC-MS/MS data from 19,075 extracts and developed plantMASST reference database encompassing 246 botanical families, 1,469 genera, 2,793 species. This taxonomically focused facilitates exploration plant-derived molecules using tandem mass spectrometry (MS/MS) spectra. tool will aid in drug discovery, biosynthesis, (chemo)taxonomy,...
Croton matourensis Aubl. (synonym lanjouwensis Jabl.), popularly known as "orelha de burro", "maravuvuia", and/or "sangrad'água", is a medicinal plant used in Brazilian folk medicine depurative and the treatment of infections, fractures, colds. In this work, we investigated chemical composition vitro cytotoxic vivo antitumor effects essential oil (EO) from leaves C. collected Amazon rainforest. The EO was obtained by hydrodistillation using Clevenger-type apparatus characterized...
Cyperus articulatus L. (Cyperaceae), popularly known in Brazil as “priprioca” or “piriprioca”, is a tropical and subtropical plant used popular medical practices to treat many diseases, including cancer. In this study, C. rhizome essential oil (EO), collected from the Brazilian Amazon rainforest, was addressed relation its chemical composition, induction of cell death vitro inhibition tumor development vivo, using human hepatocellular carcinoma HepG2 cells model. EO obtained by...
Conobea scoparioides (Cham. & Schltdl.) Benth. (syn. Sphaerotheca Cham. Schldtl.) (Plantaginaceae), popularly known as "pataqueira", "vassourinha-do-brejo" and/or "hierba-de-sapo", is a popular medicinal plant used to treat leishmaniasis, pain and beriberi. In addition, inhibition of cell adhesion, antioxidant, cytotoxic leishmanicidal activities compounds or fractions C. have been reported. the present work, chemical constituents in vitro vivo anti-liver cancer potential essential oil (EO)...
Virola surinamensis (Rol. ex Rottb.) Warb. (Myristicaceae), popularly known in Brazil as "mucuíba", "ucuúba", "ucuúba-branca" or "ucuúba do igapó", is a medicinal plant used to treat variety of diseases, including infections, inflammatory processes and cancer. In the present work, we investigated chemical constituents vitro vivo inhibition human colon carcinoma HCT116 cells by essential oils obtained from bark (EOB) leaves (EOL) V. surinamensis. EOB EOL were hydrodistillation analyzed via...
Abstract Aniba parviflora ( Meisn .) Mez (Lauraceae) is an aromatic plant of the Amazon rainforest, which has a tremendous commercial value in perfumery industry; it popularly used as flavoring sachets and baths. In Brazilian folk medicine, A. to treat victims snakebites. Herein, we analyzed chemical composition bark essential oil (EO) its effect on growth human hepatocellular carcinoma HepG2 cells vitro vivo . EO was obtained by hydrodistillation characterized GC‐MS GC‐FID. The main...
Essential oils from Amazonian species are gaining increasing interest worldwide due to their medicinal and cosmetic applications; however, the relation among chemical constituents biological properties not well explored. Therefore, present research aims obtain an understanding of bioactivity compounds in essential plants Annonaceae family (Bocageopsis pleiosperma, Onychopetalum amazonicum, Unonopsis duckei, U. floribunda, rufescens, U.stipitata, guatterioides, Duguetia flagellaris Xylopia...
AbstractAbstractXylopia benthamii (Annonaceae) is a plant with limited phytochemical and pharmacological evidence. Thus, using LC-MS/MS, we performed exploratory analyses of the fruit extract X. benthamii, resulting in tentative identification alkaloids (1–7) diterpenes (8–13). Through application chromatography techniques two kaurane were isolated, xylopinic acid (9) ent-15-oxo-kaur-16-en-19-oic (11). Their structures established spectroscopy (NMR 1D/2D) mass spectrometry. The isolated...