A5100774098- Video Coding and Compression Technologies
- HIV/AIDS Research and Interventions
- Advanced Vision and Imaging
- Advanced Data Compression Techniques
- Smart Agriculture and AI
- HIV, Drug Use, Sexual Risk
- Global Maternal and Child Health
- Diabetic Foot Ulcer Assessment and Management
- Medical Image Segmentation Techniques
- Microbial Natural Products and Biosynthesis
- Oral Health Pathology and Treatment
- Tumors and Oncological Cases
- Cytokine Signaling Pathways and Interactions
- Tree Root and Stability Studies
- COVID-19 diagnosis using AI
- Bone and Joint Diseases
- Sarcoma Diagnosis and Treatment
- 3D Printing in Biomedical Research
- Cancer Immunotherapy and Biomarkers
- Genomics and Phylogenetic Studies
- Plant Surface Properties and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Treatment and Research
- Poverty, Education, and Child Welfare
- Adolescent Sexual and Reproductive Health
Jilin University
2023-2024
Sun Yat-sen Memorial Hospital
2022-2024
Sun Yat-sen University
2022-2024
Union Hospital
2024
Brown University
2024
Fujian Medical University
2024
Sichuan University
2023
West China Hospital of Sichuan University
2023
Ministry of Education of the People's Republic of China
2023
Yunnan University
2023
Abstract The critical bone defect is still an urgent problem in the field of repair. Here, we reported a new type chitosan (CS)–hydroxyapatite (HAP) scaffolds based on lyophilized platelet-rich fibrin (L-PRF) for releasing abundant growth factors to realize their respective functions. It also has strong mechanical properties maintain stability repair environment. However, acid-soluble CS hydrogels often contain toxic and organic solvents. Moreover, chemical agents may be used cross-linking...
Abstract Background Docetaxel resistance represents a significant obstacle in the treatment of prostate cancer. The intricate interplay between cytokine signalling pathways and transcriptional control mechanisms cancer cells contributes to chemotherapeutic resistance, yet underlying molecular determinants remain only partially understood. This study elucidated novel mechanism mediated by autocrine interaction interleukin-11 (IL-11) its receptor subunit alpha(IL-11RA), culminating activation...
Dermatofibrosarcoma protuberans (DFSP) is a rare and marginal cutaneous sarcoma of intermediate-grade malignancy, for which the genomic landscape remains unclear. Understanding DFSP will help to further classify pathway malignant development in soft tissue.To identify comprehensive molecular pathogenesis DFSP.In this study, features, with 53 tumour-normal pairs DFSP, were revealed by whole-genome sequencing.The mutational signature 1 (C > T mutation at CpG dinucleotides) featured resulting...
Background: Severe complications may cause a fatal or disabling outcome in patients with Rickettsia japonica infection but are poorly understood. Methods: We identified 11 only metagenomics next generation sequencing (mNGS) during April to November 2021 at Yichang Central People's Hospital, China. Clinical data were obtained through review of medical records. Results: Most realized that they had symptoms about one two days after being bitten. Fever (91%), pulmonary effusion rash erythema...
Abstract Background Prostate cancer is a leading cause of cancer-related deaths among men worldwide. Docetaxel chemotherapy has proven effective in improving overall survival patients with castration-resistant prostate (CRPC), but drug resistance remains considerable clinical challenge. Methods We explored the role Ribonucleotide reductase subunit M2 (RRM2), gene associated senescence, sensitivity to docetaxel. evaluated RRM2 expression, docetaxel resistance, and ANXA1 expression cell lines...
Multiple myeloma (MM) is an incurable malignancy of plasma cells. Ivermectin a US Food and Drug Administration-approved drug for antiparasitic use. Here, we showed that ivermectin exerted anti-MM effects significantly synergized with proteasome inhibitors in vitro vivo. alone exhibited mild activity vitro. Further investigation suggested inhibited the nucleus by repressing nuclear import subunits, such as PSMB5-7 PSMA3-4. Therefore, treatment caused accumulation ubiquitylated proteins...
Accurate and reliable PV power probabilistic-forecasting results can help grid operators market participants better understand cope with energy volatility uncertainty improve the efficiency of dispatch operation, which plays an important role in application scenarios such as trading, risk management, scheduling. In this paper, innovative deep learning quantile regression ultra-short-term power-forecasting method is proposed. This employs a two-branch architecture to forecast conditional...
In the state-of-the-art video coding standard, H.264/AVC, encoder is allowed to search for its prediction signals among a large number of reference pictures that have been decoded and stored in decoder enhance efficiency. Therefore, computation complexity motion estimation (ME) increases linearly with picture. Many fast multiple frame ME algorithms proposed, whose performance, however, will be considerably degraded hardwired design due macroblock (MB) pipelining architecture. Considering...
Although TP53 and SPOP are frequently mutated in metastatic prostate cancer (PCa), their prognostic value is ambiguous, large sample studies lacking, especially when they co-occur with other genetic alterations. Genomic data patients' clinical characteristics PCa were downloaded from the cBioPortal database. We extensively analyzed gene alterations different mutation status of SPOP. further subdivided into subgroups based on status, then evaluated value. Two classification systems for...
This paper presents an encoder core architecture for context-based adaptive binary arithmetic coding (CABAC) in H.264/AVC main profile. The throughput of CABAC is usually limited due to i) bit-wise processing, ii) complicated data dependency, and iii) variant iteration times each symbol. adopts dynamic pipeline scheme improve the performance encoder. characteristics algorithm are utilized reduce latency. Meanwhile, bypass applied eliminate possible memory conflict. Proposed implemented under...
To the Editors: INTRODUCTION HIV remains a major cause of preventable morbidity and mortality in Kenya, with 100,000 new infections an estimated 62,000 deaths 2011.1 At same time, unhealthy alcohol consumption is important risk factor for acquisition2–7 progression.8 Kenya has one highest rates use worldwide,9,10 as many 13% may be attributable to use.11 Randomized controlled trials (RCTs) cognitive behavioral therapy (CBT)-based interventions addressing show promising results, increasing...
In this paper, we present an efficient architecture for deblocking filter in H.264/AVC. A novel 2-dimensional parallel memory scheme is employed order to achieve highly access both horizontal and vertical directions. By using scheme, also eliminate the need a transpose circuit. Our design implemented under 0.35/spl mu/m technology. Synthesis results show that equivalent gate count only 9.35K (not including SRAMs) when maximum frequency 100MHz.
Annual low dose computed tomography (CT) lung screening is currently advised for individuals at high risk of cancer (e.g., heavy smokers between 55 and 80 years old). The recommended practice significantly reduces all-cause mortality, but the vast majority results are negative cancer. If patients very could be identified based on individualized, image-based biomarkers, health care resources more efficiently allocated to higher reduce overall exposure ionizing radiation. In this work, we...
Background In the current report, we ask if targeting a cognitive behavioral therapy ( CBT )‐based intervention aimed at reducing hazardous alcohol consumption to HIV ‐infected persons in East Africa would have favorable value costs that are feasible for scale‐up. Methods Using computer simulation inform prevention decisions Africa, compared 4 different strategies intervention—(i) all attending clinic; (ii) only those patients pre‐antiretroviral ART ) stages of care; (iii) receiving ; and...
Smoking is the leading cause of preventable death worldwide. Cigarette smoke includes thousands chemicals that are harmful and tobacco-related diseases. To date, causality between human exposure to specific compounds effects unknown. A first step in closing gap knowledge has been measuring smoking topography, or how smoker smokes cigarette (puffs, puff volume, duration). However, current gold-standard approaches topography involve expensive, bulky, obtrusive sensor devices, creating...
Introduction Link4Health, a cluster-RCT, demonstrated the effectiveness of combination strategy targeting barriers at various HIV continuum steps on linkage to and retention in care; showing achieving care within 1 month plus 12 months after testing for people living with (RR 1.48, 95% CI 1.19–1.96, p = 0.002). In addition standard care, Link4Health included: 1) Point-of-care CD4+ count testing; 2) Accelerated ART initiation; 3) Mobile phone appointment reminders; 4) Care prevention package...
Sorbitol could lower the viscosity, yield stress, flow behavior index, storage modulus, loss and elevated consistency tangent of peanut butter. It made butter have greater mobility more obvious liquid characteristic. reduce hardness stickiness butter, thereby solving problem poor spreadability traditional (stability) The microstructure sorbitol added system was well-distributed compact. had a higher degree adhesion, stronger shear resistance anti-thixotropy. enhance color aroma make its...
<b><sc>Abstract.</sc></b> Robotic pruning is a solution to address the issues of labor shortages and high associated costs apple tree. According requirements high-spindle-shaped trees in dormant period, autonomous precise operation robot realized presence obstacles. The kinematic model tree manipulator was established by DH-parameter method. virtual canopy were MATLAB. workspace collision-free path planning six-rotational (6R) degrees freedom (DoF) robotic with an end-effector explored. A...