- Neurotransmitter Receptor Influence on Behavior
- Schizophrenia research and treatment
- Organ Donation and Transplantation
- Mental Health and Psychiatry
- Substance Abuse Treatment and Outcomes
- Opioid Use Disorder Treatment
- Psychotherapy Techniques and Applications
- Healthcare Policy and Management
- Mental Health Treatment and Access
- Forensic Toxicology and Drug Analysis
- Organ Transplantation Techniques and Outcomes
- Treatment of Major Depression
- Mental Health and Patient Involvement
- Healthcare cost, quality, practices
- Renal Transplantation Outcomes and Treatments
- Primary Care and Health Outcomes
- Counseling Practices and Supervision
- Suicide and Self-Harm Studies
- Reproductive Health and Technologies
- Academic and Historical Perspectives in Psychology
- Pain Management and Opioid Use
- HIV, Drug Use, Sexual Risk
- Mental Health Research Topics
- Renal and Vascular Pathologies
- Healthcare Decision-Making and Restraints
American Enterprise Institute
2010-2023
Yale University
1996-2022
University School
2018
Ethics and Public Policy Center
2000
Princeton University
2000
VA Connecticut Healthcare System
1999
University of Pennsylvania
1996
VA Connecticut Research and Education Foundation
1992-1996
University of Connecticut
1994
UConn Health
1994
The authors' objective was to assess the frequency and nature of cocaine-induced paranoia.They interviewed 50 cocaine-dependent men consecutively admitted a 28-day rehabilitation program.Thirty-four (68%) reported highly distressing transient paranoid states in context cocaine use. who experienced paranoia did not differ from those age, race, or measures mean duration amount use before development were significantly different lifetime used by report paranoia. Paranoia became more severe...
This study was undertaken to document symptoms and changes in dopaminergic function emerging after abrupt cessation of cocaine use.After admission, 22 patients with DSM-III-R dependence were observed drug free for 3 weeks. The patient-rated Ribicoff Abstinence Rating Scale, Symptom Physical Patient Rated Anxiety Beck Depression Inventory, visual analogue scales 16 subjective states completed daily, nurses rated 13 the global anxiety depression items Short Clinical Scale. Serial blood samples...
FINALIST FOR THE LOS ANGELES TIMES BOOK PRIZE IN SCIENCE What can't neuroscience tell us about ourselves? Since fMRI--functional magnetic resonance imaging--was introduced in the early 1990s, brain scans have been used to help politicians understand and manipulate voters, determine guilt court cases, make sense of everything from musical aptitude romantic love. But although other neurotechnologies provided groundbreaking insights into workings human brain, increasingly fashionable idea that...
Collaborative on Countering the US Opioid Epidemic [8] has been focusing comprehensive and collaborative efforts to fundamentally address opioid epidemic crisis.All of these major initiatives emphasize pain education as a key component in fight against dual crises chronic epidemic.I am honored represent AAPM HHS Pain Management Task Force NAM Action contribute important our nation your behalf.The emphasizes strategic priority its mission.In coming years, we will focus defining competencies...
The aim of this study was to determine whether individuals who experience transient cocaine-induced paranoia are vulnerable psychosis.The subjects were 20 cocaine-dependent men had been using more than 5 g cocaine per week and undergoing substance abuse treatment; half reported binge-limited paranoia. assessed with the Perceptual Aberration Scale Magical Ideation Scale, self-report measures symptoms thought precede development functional combined scores on strongly correlated a history...
Although cocaine is a potent serotonin (5-HT) reuptake blocker, the role of 5-HT systems in craving and relapse humans has been unclear. The authors evaluated whether acute reductions central synthesis modulated for cocaine-dependent patients.Twenty-five male inpatients were exposed to cocaine-craving cues while their levels lowered during placebo condition counterbalanced, double-blind design. reduced by rapidly lowering plasma its precursor, tryptophan; tryptophan stimulating protein with...
The authors selected at random every fourth inpatient chart (N = 79) of patients enrolled in a schizophrenia clinic for analysis substance use patterns and psychiatric hospitalizations. Patients were divided into three groups based on operationally defined lifetime drug histories: a) cocaine other use; b) without cocaine; c) no use. All available hospital records examined presenting symptoms psychosocial functioning admission, neuroleptic dosing, management. Cocaine-using schizophrenics had...
Previous research has shown a high prevalence of comorbid personality disorders among individuals seeking treatment for cocaine dependence. We studied axis II (using the Structured Clinical Interview DSM-III-R Personality Disorders [SCID-II]) in 50 patients admitted inpatient rehabilitation. All met lifetime criteria dependence and reported use during month before admission. Seventy percent at least one diagnosis; mean number diagnoses these was 2.54 (range, to six). The most common...
Background: Association studies between marker alleles at the D2 dopamine receptor gene (DRD2) and various psychiatric illnesses have produced conflicting results. Reports of allelic associations were originally made with alcoholism, but then extended to other disorders; there has been a series positive reports suggesting an association DRD2 substance dependence in European-American (EA) subjects.Methods: In attempt replicate reported alleles, dependence, severity we studied allele...
Glucocorticoid preparations are used commonly in the treatment of many diseases children and adolescents. Although their physiologic side effects have been described well, psychiatric these medications received little attention. Limited data suggest that disturbances affect behavior may occur 25-50% receiving glucocorticoid. These steroid-induced mental changes be underrecognized children, yet can considerable impact on social psychological functioning outcome. An enhanced awareness...
Cross sectional areas of buccal floor elevator (interhyoideus, IH) and depressor (orbitohyoideus, OH) muscles were measured in tadpoles from 50 anuran species (11 families, 29 genera). Interspecifically, IH OH cross scale as the 2.32 2.16 power body length. These values are not significantly different 2 (isometry). The ratio IH/OH area was examined for developmental series four: Xenopus laevis, Rhinophrynus dorsalis, Hyla regillUa Bufo terrestris. With exception B. terrestris there no...