Charles C. Lee

ORCID: 0000-0001-9884-5893
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About
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Research Areas
  • Orthopedic Infections and Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Mesenchymal stem cell research
  • 3D Printing in Biomedical Research
  • Infective Endocarditis Diagnosis and Management
  • Pluripotent Stem Cells Research
  • Bacterial biofilms and quorum sensing
  • Global Healthcare and Medical Tourism
  • Spinal Cord Injury Research
  • Bacterial Identification and Susceptibility Testing
  • Infectious Diseases and Mycology
  • Wound Healing and Treatments
  • Endometriosis Research and Treatment
  • Mycobacterium research and diagnosis
  • Cerebral Venous Sinus Thrombosis
  • Nerve injury and regeneration
  • Infectious Diseases and Tuberculosis
  • Breast Cancer Treatment Studies
  • Diabetic Foot Ulcer Assessment and Management
  • Breast Implant and Reconstruction
  • Pituitary Gland Disorders and Treatments
  • Body Contouring and Surgery

Pennsylvania State University
2023

University of California, Davis
2011-2021

University of Rochester Medical Center
2016-2020

University of Rochester
2018

Matrix Research (United States)
2011

Management of foot salvage therapy (FST) for diabetic infections (DFI) is challenging due to the absence reliable diagnostics identify etiologic agent and prognostics justify aggressive treatments. As Staphylococcus aureus most common pathogen associated with DFI, we aimed develop a multiplex immunoassay IgG in serum medium enriched newly synthesized anti-S. antibodies (MENSA) generated from cultured peripheral blood mononuclear cells DFI patients undergoing FST. Wound samples were collected...

10.1128/iai.00629-18 article EN Infection and Immunity 2018-10-01

Noninvasive diagnostics for Staphylococcus aureus musculoskeletal infections (MSKI) remain challenging. Abs from newly activated, pathogen-specific plasmablasts in human blood, which emerge during an ongoing infection, can be used diagnosing and tracking treatment response diabetic foot infections. Using multianalyte immunoassays on medium enriched synthesized (MENSA) Ab-secreting cells, we assessed anti-S. IgG responses 101 MSKI patients (63 culture-confirmed S. aureus, 38 aureus-negative)...

10.4049/immunohorizons.2000024 article EN cc-by-nc ImmunoHorizons 2020-06-01

The major limitations of clinical outcome predictions osteomyelitis mediated by Staphylococcus aureus (S. aureus) are not specific and definitive. To this end, current studies aim to investigate host immune responses trend changes the iron-regulated surface determinant (Isd) IsdA, IsdB, IsdH, cell wall-modifying proteins amidase (Amd) glucosaminidase (Gmd), secreted virulence factor chemotaxis inhibitory protein S. (CHIPS) staphylococcal complement inhibitor (SCIN) longitudinally discover...

10.1002/jor.24961 article EN Journal of Orthopaedic Research® 2020-12-18

With an increasing focus on multimodal pain control to reduce opioid requirements, regional and local anesthesia techniques have been investigated in bilateral reduction mammaplasty with variable results. The purpose of this study is compare tumescent pectoral nerve block II (PECS II) patients undergoing respect postoperative nausea, consumption, length stay, cost.A retrospective review for macromastia between November 2020 December 2021 was performed. Demographic information, operative...

10.1097/sap.0000000000003521 article EN Annals of Plastic Surgery 2023-03-17

Background Medical tourism is an increasingly popular practice among cosmetic surgery patients. These procedures place patients at risk of infection by rapidly growing Mycobacterium . Rapidly (RGM) a relatively rare within developed nations. Management options vary, although all pose significant morbidity to We present 2 cases treated our institution and comprehensive literature review RGM in who have undergone developing nations, analyzing its associated morbidity. Methods This...

10.1097/ipc.0000000000001142 article EN Infectious Diseases in Clinical Practice 2022-09-01
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