A5039011272- Memory and Neural Mechanisms
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Receptor Mechanisms and Signaling
- Primate Behavior and Ecology
- Animal Behavior and Reproduction
- Stress Responses and Cortisol
- Olfactory and Sensory Function Studies
- Zebrafish Biomedical Research Applications
Neuroelectronics Research Flanders
2023-2024
Centre Interdisciplinaire de Recherche en Biologie
2021-2023
Inserm
2017-2023
Collège de France
2022-2023
Université Paris Sciences et Lettres
2022-2023
Centre National de la Recherche Scientifique
2017-2023
Neurosciences Paris-Seine
2017-2018
Sorbonne Université
2017-2018
Institut de Biologie Paris-Seine
2017-2018
Highly synchronous neuronal assembly activity is deemed essential for cognitive brain function. In theory, such synchrony could coordinate multiple areas performing complementary processes. However, cell assemblies have been observed only in single structures, typically cortical areas, and little known about their with downstream subcortical as the striatum. Here, we demonstrate distributed activated at high (∼10 ms) spanning prefrontal cortex addition to including neurons different...
Prefrontal cortical and striatal areas have been identified by inactivation or lesion studies to be required for behavioral flexibility, including selecting processing of different types information. In order identify these networks activated selectively during the acquisition new reward contingency rules, rats were trained discriminate orientations bars presented in pseudorandom sequence on two video monitors positioned behind goal sites a T-maze with return arms. A second group already...
Introduction Dopamine release in the forebrain by midbrain ventral tegmental nucleus (VTA) and substantia nigra pars compacta (SNc) neurons is implicated reward processing, goal-directed learning, decision-making. Rhythmic oscillations of neural excitability underlie coordination network have been reported these dopaminergic nuclei at several frequency bands. This paper provides a comparative characterization frequencies local field potential single unit activity, highlighting some...
Abstract In the canonical interpretation of phasic activation dopaminergic neurons during Pavlovian conditioning, initially cell firing is triggered by unexpected rewards. Upon learning, instead follows reward-predictive conditioned stimulus. When expected rewards are withheld, inhibited. Here, we recorded optogenetically identified ventral tegmental area (VTA) in mice training successive operant sensory discrimination tasks. A delay was imposed between nose-poke choices and trial outcome...
Summary Individuality is a ubiquitous and well-conserved feature among animal species. The behavioral patterns of individual animals affect their respective role in the ecosystem prospects for survival. Even though some factors shaping individuality have been identified, mechanisms underlying individuation are poorly understood generally considered to be genetics-based. Here we devised large environment where mice live continuously, observed that individuality, measured by both social...
Abstract Prefrontal cortical and striatal areas have been identified by inactivation or lesion studies to be required for behavioral flexibility, including selecting processing of different types information. In order identify these networks activated selectively during acquisition new reward contingency rules, rats were trained discriminate orientations bars presented in pseudo-random sequence on two video monitors positioned behind the goal sites a T maze with return arms. A second group...
Abstract Dopamine release in the forebrain by midbrain ventral tegmental nucleus (VTA) and substantia nigra pars compacta (SNpc) neurons is implicated reward processing, goal-directed learning, decision-making. Rhythmic oscillations of neural excitability underlie coordination network have been reported these dopaminergic nuclei at several frequency bands. This paper provides a comparative characterization frequencies local field potential single unit activity, highlighting some behavioral...