A5100715686- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Cells and Metastasis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gut microbiota and health
- AI in cancer detection
- Hemostasis and retained surgical items
- Metastasis and carcinoma case studies
- Neuroblastoma Research and Treatments
- 3D Printing in Biomedical Research
- Cancer, Hypoxia, and Metabolism
- Amyotrophic Lateral Sclerosis Research
- Cellular Mechanics and Interactions
- Oral and Maxillofacial Pathology
Children's Hospital of Los Angeles
2023-2025
Inha University
2015-2024
Shinhwa Medical (South Korea)
2023-2024
Dongwha Pharm (South Korea)
2024
Inha University Hospital
2009-2023
University of Southern California
2023
National Institute of Food and Drug Safety Evaluation
2019-2020
Weatherford College
2020
Iowa Digestive Disease Center
2020
Yale University
2016-2018
High-quality bowel preparation is necessary for colonoscopy. A few studies have been conducted to investigate improvement in quality through patient education. However, the effect of education on has not well studied. randomized and prospective study was conducted. All patients received regular instruction during a pre-colonoscopy visit. Those scheduled colonoscopy were randomly assigned view an educational video (video group) day before colonoscopy, or non-video (control) group. Qualities...
Glioblastoma multiforme is a heterogeneous and infiltrative cancer with dismal prognosis. Studying the migratory behavior of tumor-derived cell populations can be informative, but it places high premium on precision in vitro methods relevance vivo conditions. In particular, analysis 2D migration may not reflect invasion into 3D extracellular matrices vivo. Here, we describe method that allows time-resolved studies primary single-cell resolution fibrillar surface closely mimics migration. We...
OBJECTIVES: Successful biliary cannulation is a prerequisite and important component of endoscopic retrograde cholangiopancreatography, but conventional methods (CCMs) have postendoscopic cholangiopancreatography pancreatitis (PEP) rate 14.1% in patients at high risk for PEP. The aim this study was to evaluate the effectiveness safety needle-knife fistulotomy (NKF), compared with CCM, when used primary access developing METHODS: A total 207 one or more factors PEP were prospectively...
Mucinous cystic neoplasms (MCN) and serous (SCN) account for a large portion of solitary pancreatic (PCN). In this study we implemented convolutional neural network (CNN) model using ResNet50 to differentiate between MCN SCN. The training data were collected retrospectively from 59 49 SCN patients two different hospitals. Data augmentation was used enhance the size quality datasets. Fine-tuning approaches utilized by adopting pre-trained transfer learning while selected layers. Testing...
Primary leiomyoma of the respiratory tract is a rare disease. Based on our experience, we investigated its clinical characteristics and outcomes treatment. Between 1997 2008, 16 patients in institution (nine male, seven female) were found to have primary tract. The median patient age was 46.5 years (range 17-66 years). tumor located trachea four patients, carina main bronchus four, intermedius lobar or segmental two, lung parenchyma two. Tumor removal through bronchoscopic intervention using...
It has been suggested that oxidative stress is one of the pathomechanisms underlying amyotrophic lateral sclerosis (ALS), and thus antioxidants such as uric acid (UA) could reduce might be beneficial in prevention or treatment this disease. The objective study was to prospectively investigate serum UA levels Korean ALS patients relate them disease progression. healthy controls who were individually well-matched for sex, age, body mass index (BMI) underwent blood testing levels, analyzed...
AIM:To evaluate the usefulness of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) in differentiating between pancreatic adenocarcinomas and other disease. METHODS:This retrospective cohort study evaluated 90 patients who were seen November 2010 May 2013.All these had solid masses that a hypoechoic appearance on EUS.All underwent CH-EUS to this diagnostic method's usefulness.The mass lesions observed classified into three categories based their echo intensity: hypoenhanced,...
Abstract Background Endoscopic papillary large balloon dilation (EPLBD) without prior endoscopic sphincterotomy (EST) produces excellent outcomes for the treatment of common bile duct (CBD) stones. However, it remains unclear how EPLBD alone compare with those EST. In this study, we assessed safety and therapeutic vs. EST removal Methods This prospective, multicenter study was conducted on 200 patients stones ≥ 10 mm in diameter. Patients were randomly assigned to an group (n = 100) or 100)....
Abstract Background and study aims A new hemostatic adhesive powder (UI-EWD) was developed to reduce high rebleeding rates technical challenges associated with application of currently available powders. The aim the current assess performance UI-EWD for nonvariceal upper gastrointestinal bleeding (NVUGIB). Patients methods total 56 consecutive patients that received monotherapy endoscopic hemostasis due NVUGIB were retrospectively reviewed. Main outcomes success immediate within 30 days....
Abstract Background Gastrointestinal tumor bleeding remains a clinical challenge because it is difficult to treat with conventional endoscopic hemostatic options. Recently, an powder (UI-EWD) was developed and reported provide effective control of upper gastrointestinal bleeding. The aim current study evaluate the feasibility efficacy this novel in Methods A total 41 consecutive patients were included. UI-EWD applied all as auxiliary method salvage therapy or monotherapy during treatment....
Glioblastoma (GBM) remains one of the most aggressive adult cancers, with limited treatment options due to an incomplete understanding its biology. GBM exhibits different transcriptional subtypes, among which mesenchymal (mGBM) variant is associated a particularly nature and poor outcomes. Developing models that capture mGBM phenotypes could offer new insights into biology therapeutic vulnerabilities. However, lack in vitro for has posed challenges investigating subtype. Here, we present...
Abstract Neuroblastoma (NB), the most common extracranial solid tumor in children, exhibits intra-tumoral heterogeneity with two interconvertible identities: adrenergic (ADRN) and mesenchymal (MES). MES cells display phenotypes associated metastasis resistance to therapies compared ADRN. Thus, reprogramming of ADRN may contribute poor NB outcomes, process requires further elucidation improve clinical outcomes. The extracellular matrix (ECM), a critical component microenvironment (TME),...
BACKGROUND Despite advancements, endoscopic retrograde cholangiopancreatography (ERCP) poses challenges, including the risk of post-ERCP pancreatitis and difficulty biliary cannulation. AIM To compare dome tapered tip sphincterotomes, focusing on their efficacy in achieving successful cannulation reducing incidence pancreatitis. METHODS In this prospective, single-blind, randomized pilot study conducted at Inha University Hospital, 85 patients undergoing ERCP were equally divided into...
Risk Factors for Long-term Outcomes after Initial Treatment in HepatolithiasisHepatobiliary complications, such as stone recurrence, recurrent cholangitis, liver abscess, secondary biliary cirrhosis, and cholangiocarcinoma may occur treatment hepatolithiasis.However, few previous studies have addressed the risk factors longterm outcomes initial treatment.Eighty-five patients with newly diagnosed hepatolithiasis, actively treated constituted cohort of this retrospective study.Patients were by...
Although endoscopic ultrasonography (EUS) is the first-choice imaging modality for predicting invasion depth of early gastric cancer (EGC), prediction accuracy EUS significantly decreased when EGC combined with ulceration.The aim present study was to compare and conventional endoscopy (CE) determining EGC. In addition, various clinic-pathologic factors affecting diagnostic EUS, a particular focus on ulcer shapes, were evaluated.We retrospectively reviewed data from 236 consecutive patients...
Background. Cyclophosphamide is an alkylating agent and was traditionally known to potentiate the renal action of vasopressin. Although low-dose intravenous pulse cyclophosphamide therapy being used extensively in treatment malignant rheumatological diseases, there have been only a few case reports cyclophosphamide-induced hyponatraemia. Methods. Clinical data were retrospectively analysed from 84 patients (42 lupus nephritis; 42 non-Hodgkin's lymphoma; total 112 episodes) admitted for...
Overexpression of recepteur d'Origine nantais (RON) and urokinase plasminogen activator receptor (uPAR) have been observed in human gastric cancers. However, the interaction between RON uPAR cancer is unclear. The present study investigated effect macrophage-stimulating protein (MSP, ligand) on expression underlying signal pathways AGS cells. messenger RNA was induced by MSP a time- concentration-dependent manner. also promoter activity. introduction RON-specific small interfering (siRNA)...