Makoto Sakai

ORCID: 0000-0001-9928-2375
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About
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Research Areas
  • Radiation Therapy and Dosimetry
  • Advanced Radiotherapy Techniques
  • Radiation Detection and Scintillator Technologies
  • Medical Imaging Techniques and Applications
  • Nuclear Physics and Applications
  • Dental materials and restorations
  • Radiation Effects in Electronics
  • Advanced X-ray and CT Imaging
  • Dental Implant Techniques and Outcomes
  • Economic and Technological Developments in Russia
  • Child and Adolescent Psychosocial and Emotional Development
  • Speech and Audio Processing
  • Boron Compounds in Chemistry
  • Face and Expression Recognition
  • Luminescence Properties of Advanced Materials
  • Mental Health Research Topics
  • Cancer Immunotherapy and Biomarkers
  • Head and Neck Cancer Studies
  • Ion-surface interactions and analysis
  • Esophageal Cancer Research and Treatment
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Gastric Cancer Management and Outcomes
  • Usability and User Interface Design
  • Web Data Mining and Analysis
  • Nutrition and Health in Aging

Gunma University Hospital
2016-2025

Gunma University
2016-2024

Nagoya University
2008-2024

Toshiba (Japan)
2000-2022

Chukyo University
2013-2021

Osaka University
2007-2015

Denso (United States)
2008-2010

Denso (Japan)
2007-2009

Nitto (Japan)
2007-2009

Museum of Japanese Art Yamato Bunkakan
2009

Three ways in which electrical, intracranial reinforcement is reputed to differ from conventional were tested an experiment equated the form of responses being reinforced and response-reinforcement relation. Four groups rats performed instrumental or consummatory by sugar. In no comparison did kind produce a difference, but every response difference. It inferred that differences between are artifacts.

10.1126/science.148.3675.1357 article EN Science 1965-06-04

Abstract Secondary electron bremsstrahlung (SEB) has been proposed for range verification in particle therapy. However, the uncertainty range-shift estimation attributed to high statistical noise from small numbers of carbon-ion irradiation remains unclear. This simulation study evaluated SEB-based estimations under conditions limited carbon ions. The simulated SEB images were generated by irradiating an acrylic target with monoenergetic beams and calculating energy deposited onto a cadmium...

10.35848/1347-4065/adc21b article EN Japanese Journal of Applied Physics 2025-03-18

We have been developing a medical imaging technique using Compton camera. This study evaluates the feasibility of clear with 99mTc and 18F simultaneously, demonstrates in vivo and/or 18F. used camera silicon cadmium telluride (Si/CdTe) semiconductors. estimated performance for 141 keV 511 gamma rays from 22Na, respectively. Next, we simultaneously imaged point sources to evaluate cross-talk artifacts produced by higher energy gamma-ray background. Then, experiments, three rats were injected...

10.1088/1361-6560/aae1d1 article EN Physics in Medicine and Biology 2018-09-17

A feasibility study on the imaging of monochromatic carbon-ion beams for therapy was performed. The evaluation based Monte Carlo simulations and beam-irradiation experiments, using a pinhole x-ray camera, which measured secondary electron bremsstrahlung (SEB). simulation results indicated that trajectories with injection energies 278, 249 218 MeV/u in water phantom, were clearly imaged by measuring SEB from 30 to 60 keV, camera. Bragg-peak positions these three located at where ratios counts...

10.1088/1361-6560/aaa17c article EN Physics in Medicine and Biology 2017-12-13

Psychological stress has become a major concern, potentially leading to diverse health problems including psychopathology such as depression and anxiety. Transactional Model of Stress Coping is an established model, conceptualizing stressful experiences via person-environment relationship. This cross-sectional study aimed explore the pathway from depression/anxiety, with focus on self-criticism (inadequate-self hated-self) self-reassurance (reassured-self) in Czech students who suffered high...

10.1007/s11469-021-00516-z article EN cc-by International Journal of Mental Health and Addiction 2021-03-10

Abstract In cancer therapy today, carbon ion radiotherapy is used mainly as monotherapy, whereas cisplatin concomitantly with X-ray radiotherapy. The effectiveness of concomitant ions and unclear. To obtain the information on mechanisms potentially shared between or X-rays cisplatin, we assessed correlation sensitivity to single treatments. 20 human cell lines, strongly correlated indicating presence target mechanisms. Interestingly, was much weaker than that different cisplatin. Assessment...

10.1038/srep40588 article EN cc-by Scientific Reports 2017-01-16

In this study, we performed on-beam monitoring of 511 keV annihilation gamma emissions using a Compton camera. Beam experiments were conducted carbon ion beams 290 MeV/u irradiated on polymethyl methacrylate (PMMA) phantom. The intensity the was 3 × 109 particles per pulse, with 20 pulses minute. A camera based silicon/cadmium telluride (Si/CdTe) detector used to monitor rays emitted from We successfully reconstructed energy events and developed images simple back-projection method....

10.1088/1361-6560/ab00b2 article EN Physics in Medicine and Biology 2019-01-23

Pure titanium cast plate denture produced by Ohara's casting system were inserted in eight patients. The pure dentures enabled satisfactory fitness and had good adaptability to the mucosal surface. Furthermore, they are lighter weight than conventional dentures. X-ray examination revealed some defects, but these defects not serious enough be conducive damages. Follow-up observation of patients with indicated no clinical problems. However, inadequate adhesiveness resin was a technical problem...

10.4012/dmj.7.39 article EN Dental Materials Journal 1988-01-01

Abstract We have been developing a medical imaging system using Compton camera and demonstrated the ability of for 99m Tc-DMSA accumulated in rat kidneys. In this study, we performed experiments human body phantom to confirm its applicability imaging. Preliminary simulations were conducted digital with varying activity ratios between kidney trunk regions. Gamma rays (141 keV) generated detected by based on silicon cadmium telluride (Si/CdTe) detector. images reconstructed list mode median...

10.1038/s41598-019-49130-z article EN cc-by Scientific Reports 2019-09-09

The purpose of this research is to detect low usability web pages from the behavior users, such as browsing time, mouse movement and eye movement. We experimented investigate relation between quantitative data viewing users evaluation by subjects. analyzed using discriminant analysis. Low pages, 94.4% (17pages / 18pages = detectable pages) were moving speed gazing points amount wheel rolling a mouse. Moreover, detection reduced number which should be evaluated half (46% 89 192 detected all pages).

10.1145/1134285.1134365 article EN Proceedings of the 44th International Conference on Software Engineering 2006-05-28

Optical properties of granular metal systems prepared by alternate vacuum deposition Ag and ${\mathrm{MgF}}_{2}$ have been studied. Mean thickness island films spacer layers were about 0.2 5 nm, respectively. Three samples consisting 1, 10, 50 prepared, which are denoted as ${S}_{1}$, ${S}_{10}$, ${S}_{50}$, ${S}_{1}$ well explained the simple formula for two-dimensional (2D) system. Those ${S}_{50}$ Bruggeman theory (BT) 3D system rather than Maxwell-Garnett (MGT). ${S}_{10}$ could not be...

10.1103/physrevb.32.2126 article EN Physical review. B, Condensed matter 1985-08-15

A high resolution noncontact optical sensor for surface roughness has been developed. The principle of the is based on astigmatic focus error detection, which employed in pickup disk players. First, measuring method and system arrangement are described detail. Then, results obtained by this compared with those precise diamond stylus several different types surfaces. light source newly developed apparatus a diode laser an output power 2 mW wavelength 790 nm. objective lens standard microscope...

10.1117/12.7976710 article EN Optical Engineering 1988-06-01

A Compton camera is a device for imaging radio-source distribution without using mechanical collimator. Ordered-subset expectation-maximization (OS-EM) widely used to reconstruct images. However, the OS-EM algorithm tends over-concentrate and amplify noise in reconstructed image. It is, thus, necessary optimize number of iterations develop high-quality images, but this has not yet been achieved. In paper, we apply median filter an introduce root prior (MRP-EM) overcome problem. MRP-EM,...

10.1371/journal.pone.0229366 article EN cc-by PLoS ONE 2020-03-06

The application of annihilation gamma-ray monitoring to the adaptive therapy carbon ion radiotherapy (C-ion RT) requires identification peak intensity position and differentiation gamma rays generated at C-ion-irradiated site from those transported unirradiated sites. Real-time C-ion-induced was effected using a Compton camera in mouse model. An adult C57BL/6 anesthetized, C-ion beams were directed into abdomen 1 × 109 particles/s for 20 s. 511 keV rays, by interaction between irradiated...

10.3389/fonc.2020.00635 article EN cc-by Frontiers in Oncology 2020-05-19

Abstract We evaluated an estimation ability of shifts therapeutic carbon-ion beams owing to cavities in a polyethylene target by measuring prompt X-rays emitted from beam trajectories. Carbon-12 having the energy 241.5 MeV u −1 were irradiated on target. The had square-prism-shaped cavity it. thickness was changed 3.0 0.0 cm with 0.3 steps. For each setup cavity, 7.5 × 10 carbon ions irradiated. A pinhole-type X-ray camera placed beside and utilized acquire images. trajectory gap clearly...

10.35848/1347-4065/aba22a article EN cc-by Japanese Journal of Applied Physics 2020-07-02

Background and Purpose Carbon-ion radiotherapy of prostate cancer is challenging in patients with metal implants one or both hips. Problems can be circumvented by using fields at oblique angles. To evaluate the influence setup range uncertainties accompanying field angles, we calculated rectal dose changes orthogonal a device fixed 0° 90° rotating patient couch. Material Methods Dose distributions were standard angles 90°, then 30° 60°. Setup uncertainty was simulated from −2 mm to +2 for...

10.1371/journal.pone.0153894 article EN cc-by PLoS ONE 2016-04-20
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