A5103126523- Particle accelerators and beam dynamics
- Radiation Therapy and Dosimetry
- Particle Accelerators and Free-Electron Lasers
- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Superconducting Materials and Applications
- Pulsed Power Technology Applications
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Particle Detector Development and Performance
- Advanced Semiconductor Detectors and Materials
- Gyrotron and Vacuum Electronics Research
- Laser-Plasma Interactions and Diagnostics
- Plasma Diagnostics and Applications
- IPv6, Mobility, Handover, Networks, Security
- Meningioma and schwannoma management
- Ion-surface interactions and analysis
- Nuclear Physics and Applications
- Radiation Effects in Electronics
- Cognitive Computing and Networks
- RFID technology advancements
- Internet Traffic Analysis and Secure E-voting
- PI3K/AKT/mTOR signaling in cancer
Gunma University Hospital
2010-2024
Gunma University
2010-2020
Motion Control (United States)
2013
High Energy Accelerator Research Organization
2004-2007
National Institute for Physiological Sciences
2007
Kyushu University
2005-2006
Carbon ion radiotherapy (C-ion RT) offers superior dose conformity in the treatment of deep-seated tumors compared with conventional X-ray therapy. In addition, carbon beams have a higher relative biological effectiveness protons or beams. C-ion RT for first patient at Gunma University Heavy Ion Medical Center (GHMC) was initiated March 2010. The major specifications facility were determined based on experience clinical treatments National Institute Radiological Sciences (NIRS), size and...
The efficacy and toxicity of three-fraction CyberKnife radiotherapy were evaluated in patients with brain metastases critical areas. One hundred fifty-nine 145 including tumors >10 cm(3) treated a median marginal dose 27 Gy at prescribed isodose 60%. Changes the neurological manifestations, local tumor control adverse effects investigated after treatment. surrounding volumes circumscribed 23.1 (single equivalence 14 Gy: V14) measured to evaluate risk effects. Neurological such as motor...
The efficacy and toxicity of five-fraction CyberKnife radiotherapy were evaluated in patients with large brain metastases critical areas. A total 85 78 patients, including tumors >30 cm3 (4 cm diameter) treated a median marginal dose 31 Gy at prescribed isodose 58%. Changes the neurological manifestations, local tumor control, adverse effects investigated after treatment. surrounding volumes circumscribed 28.8 (single equivalent to 14 Gy: V14) measured evaluate risk radiation necrosis....
We report an experimental demonstration of the induction synchrotron, concept which has been proposed as a future accelerator for second generation neutrino factory or hadron collider. The synchrotron supports superbunch and permits more charge to be accelerated while observing constraints transverse space-charge limit. By using newly developed acceleration system instead radio-wave devices, single proton bunch injected from 500 MeV booster ring captured by barrier bucket created step...
We have been developing a medical imaging technique using Compton camera. This study evaluates the feasibility of clear with 99mTc and 18F simultaneously, demonstrates in vivo and/or 18F. used camera silicon cadmium telluride (Si/CdTe) semiconductors. estimated performance for 141 keV 511 gamma rays from 22Na, respectively. Next, we simultaneously imaged point sources to evaluate cross-talk artifacts produced by higher energy gamma-ray background. Then, experiments, three rats were injected...
We describe a new method for estimating the beam range in heavy-ion radiation therapy by measuring ion bremsstrahlung. experimentally confirm that secondary electron bremsstrahlung process provides dominant contribution. A Monte Carlo simulation shows number of background photons from annihilation gamma rays is about 1% strength low-energy region used our estimation (63-68 keV). Agreement between experimental results and theoretical prediction characteristic shape spectrum validates...
In this study, we performed on-beam monitoring of 511 keV annihilation gamma emissions using a Compton camera. Beam experiments were conducted carbon ion beams 290 MeV/u irradiated on polymethyl methacrylate (PMMA) phantom. The intensity the was 3 × 109 particles per pulse, with 20 pulses minute. A camera based silicon/cadmium telluride (Si/CdTe) detector used to monitor rays emitted from We successfully reconstructed energy events and developed images simple back-projection method....
A single-institutional prospective study of optimal hypofractionated conformal radiotherapy for large brain metastases with high risk factors was performed based on the prediction radiation-related complications.Eighty-eight patients ≥10 cm(3) in critical areas treated from January 2010 to February 2014 using CyberKnife were evaluated. The dose and number fractions determined surrounding volume circumscribed a single equivalent (SDE) 14 Gy (V14) be less than 7 individual lesions. Univariate...
Spread-out Bragg peaks made by ridge filters or wheel range modulators are used in charged particle therapy with passive methods to achieve uniform biological responses irradiated tumors. Following the needed design filters, which were developed at National Institute of Radiological Sciences Japan, new designed using recent developments heavy-ion reactions and dosimetry. The Monte Carlo code Geant4 was calculate qualities carbon ion beams a water phantom. results obtained from simulation...
Purpose To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used astrophysical observation to test its capacity perform three-dimensional (3D) imaging. Materials Methods All animal experiments were performed according Animal Care Experimentation Committee (Gunma University, Maebashi, Japan). Flourine 18 fluorodeoxyglucose (FDG), iodine 131 (131I) methylnorcholestenol, gallium 67 (67Ga) citrate, separately...
A single rf bunch in the KEK proton synchrotron was accelerated with an induction acceleration method from injection energy of 500 MeV to 5 GeV.
A medium-energy synchrotron capable of accelerating all-ion species is proposed. The accelerator employs a strong focusing lattice for ion-beam guiding and induction acceleration longitudinal capture, which driven by switching power supply. All ions, including cluster ions in their possible arbitrary charge state, are accelerated single accelerator. Since the supply employing solid-state elements energized trigger signal, generated from bunch monitor signal produced circulating ion bunch,...
A high-energy carbon-ion radiotherapy facility is under construction at Gunma University Heavy Ion Medical Centre (GHMC). Its design was based on a study of the heavy ion National Institute Radiological Sciences (NIRS) in order to reduce size and cost facility. compact electron cyclotron resonance source (ECRIS) for University, called KeiGM, installed 2008. It almost copy prototype ECRIS Kei2 which developed by NIRS; meanwhile this produced over 1 e mA C(4+) using C(2)H(2) gas (660 W 40 kV)....
Radiofrequency identification (RFID) applications have the capability to obtain real-time information on location and properties of tagged people or objects. The efficiency safety new RFID system (UHF band, 953 MHz) were tested in our hospital. We examined whether 1 4 persons medical equipment with IC tags captured by readers a laboratory. next electric signals produced could affect devices. New radio frequency provided extensive patient helped track capital within Electric fields did not...
We studied feasibility of detection a gap which is located across beam track by measuring low-energy (63–68 keV) photons generated irradiation. An experiment was performed with the Heavy Ion Medical Accelerator in Chiba (HIMAC). A 12 C having 290 MeV/u injected on target consisting two acrylic blocks. These blocks were placed 10 mm along axis. system semiconductor detector, lead collimator slit, and borated polyethylene movable stage to detect emitted perpendicularly The position moved at 2...
A quasiadiabatic nonfocusing transition-energy crossing is proposed for suppressing any nonadiabatic and undesired features in a longitudinally separated function-type accelerator, which particles are confined by an radio-frequency voltage with adiabatic reduction of the amplitude accelerated step voltage. This new method has been examined, both theoretically experimentally.
A new particle acceleration method using pulsed induction cells was introduced in the super-bunch project at <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">KEK</b> . Unlike conventional RF acceleration, this separates functions of and confinement. As a result, is capable accelerating very long bunch beam or wide mass range particles. However, it necessary to give fast pulsed- excitation magnetic material induce an electric field accelerate...
Proof-of-principle experiments on the induction synchrotron concept are scheduled using KEK 12-GeV proton synchrotron, in which rf bunches and a superbunch will be accelerated with long step voltage generated accelerating gaps. An unavoidable droop gives an additional focusing or defocusing force longitudinal direction. It largely deforms barrier bucket confining superbunch, leading to nonuniform particle distribution. The effects serious transition energy. Longitudinal emittance blowup...
Alert fatigue, a decrease in sensitivity to alerts, is problem the medical field. In this study, survey was conducted on accidents order develop an alert that could be expected reduce fatigue. As result, related drugs are common worldwide, and need for system can detect implementation of treatment found.