The objective of this study was to analyse associations between sexualised substance use (chemsex), STI diagnoses and sexual behaviour among gay bisexual other men who have sex with accessing health clinics better inform clinical pathways. A retrospective case notes review undertaken following the introduction more detailed holistic profomas for all attending two London 1 June 2014 31 January 2015. Chemsex status documented 655/818. Overall, 30% disclosed recreational drug whom 113 (57%)...

Objectives The aim of the study was to analyse associations between chemsex and new HIV sexually transmitted infection ( STI ) diagnoses among gay, bisexual other men who have sex with GBMSM accessing sexual health clinics. Methods A retrospective case note review carried out for all attending two London clinics 1 June 2014 31 July 2015. Results Chemsex status documented 1734 1840 patients. Overall, 27.1% n = 463) disclosed current recreational drug use, whom 286 (16.5%) participation 74 409...

This is the first British Association of Sexual Health and HIV (BASHH) national guideline for management sexually transmitted enteric infections (STEI). primarily aimed level 3 sexual health clinics; however, it may also be applicable to other settings such as primary care or hospital departments where individuals with STEI present. makes recommendations on testing, management, partner notification public control STEI.

To determine patient and treatment characteristics associated with vitamin D deficiency (VDD) in an UK inner city HIV-1-positive adult cohort.Two hundred twenty-seven HIV-positive patients attending prospectively for routine blood tests winter had serum 25-hydroxyvitamin parathyroid hormone (PTH) concentrations other chemistry measured. Those without VDD were defined as having <50 nmol/L >75 nmol/L, respectively. Characteristics compared between VDD. The effects of VDD, tenofovir use, their...

<h3>Objectives</h3> To assess the impact of computer-assisted interview compared with pen and paper on disclosure sexual behaviour, diagnostic testing by clinicians, infections diagnosed referral for counselling. <h3>Methods</h3> Two-centre parallel three-arm randomised controlled open trial. Computer-generated randomisation allocation concealment using sealed envelopes. <h3>Setting</h3> Two London teaching hospital health clinics. <h3>Participants</h3> 2351 clinic attenders over age 16...

The concomitant treatment of HIV-tuberculosis co-infection is complicated by pharmacological interactions between drugs, resulting in unpredictable drug levels. We monitored efavirenz levels all tuberculosis-HIV-treated patients over 2 years. Using 800 mg/day efavirenz, high and toxicity were detected seven out nine patients, necessitating reduction or discontinuation. Polymorphisms cytochrome P450 2B6 may account for this. Therapeutic monitoring, dose a lower starting be appropriate some to...

To determine the prevalence of cryptococcal antigenemia in a UK HIV cohort and compare baseline characteristics patients with without antigenemia.

Objectives To investigate changing nutritional demographics of treated HIV-1-infected patients and explore causes obesity, particularly in women African origin. Methods We prospectively reviewed clinic attenders at an urban European HIV during four one-month periods 3-yearly intervals (2001, 2004, 2007, 2010) two consecutive whole-year reviews (2010-11 2011-12). Risk-factors for obesity were assessed by multiple linear regression. A sub-study 50 HIV-positive female investigated...

The use of previously successful antiretroviral regimens in mother-to-child transmission (MTCT) prevention will be increasingly challenged by the rising prevalence multidrug-resistant (MDR) HIV. We used enfurvitide together with an optimized backbone to prevent MTCT MDR HIV two pregnant women. measurement maternal and foetal peripheral blood levels showed no evidence transplacental transfer.

Post-exposure prophylaxis after sexual exposure (PEPSE) awareness was audited in an HIV-positive cohort. A total of 403 out 828 (48.7%) patients were PEPSE aware. Patients diagnosed post-2006 more aware; 57.2% vs. 44.2% (p = 0.0004). Men who have sex with men (MSM) 65.8% 39.1% heterosexuals < 0.0001).Younger patients, 68.1% aged 19-34 aware 45.7% those >35 years 0.0001). In the 534 reporting activity within last year, 57.5%. 216 'sometimes' or 'never' using condoms, 42.6%. 78 (9.4%)...

Our objective was to determine the prevalence of intestinal protozoa in homosexual men attending a sexually transmitted diseases (STD) clinic, compare it with previous study from same and examine relationship, if any, between presence sexual practices. Men who consecutively attended clinic gave history having had recent contact another male were invited provide stool sample for protozoological examination. Diarrhoeal samples examined by direct microscopy trophozoites cysts and, after...

To examine the incidence of urethral stricture in men Scotland during years 1982-1991 relation to changing gonococcal and non-gonococcal urethritis (NGU) over past 20 years.Retrospective study Scotland.The number new whom a diagnosis was made for obtained using Scottish Record Linkage system, cases gonorrhoea NGU from Communicable Diseases (Scotland) Unit. Age-specific rates were calculated Poisson regression model used test if there trend rate with age or time change.There highly...

Previous studies have highlighted disparities in care and outcomes HIV-positive prisoners compared to individuals the population. We audited clinical of accessing 2011. Public Health England were notified 161 with HIV time period studied. Audit proformas sent clinics reporting genitourinary medicine clinic activity dataset Thirty-two responded. Data for 151 reported by 12 clinics, other not any prisoners. Outcomes a previous audit, British Association (BHIVA) National AIDS Trust guidelines....

Squamous cell carcinoma of the penis is an uncommon cancer, though in one study it accounted for 90% all penile cancers. Its association with balanitis xerotica obliterans (BXO) a rare recognized occurrence. We describe case 46-year-old Caucasian male who first presented to our open-access clinic mild phimosis. An elective circumcision was performed and histological examination specimen showed BXO. He lost follow-up but re-presented three years later persistent tender ulcer which on biopsy...

Hypersensitivity reaction (HSR), associated with the antiretroviral abacavir, does not usually have serious outcomes unless recognised late or after rechallenge. Pharmacogenetic testing of human leucocyte antigen (HLA) B*5701 for HSR risk is being used increasingly in clinical practice backed by strong evidence among Caucasians and Hispanics.1 In Western Australian landmark studies, updated to improve diagnostic accuracy, positive predictive values (PPVs) negative (NPV) were 78.9% 99.4%,1...

Environmental contamination with DNA from Chlamydia trachomatis (CT) has previously been found in Genitourinary Medicine (GUM) clinics. There are no known cases of cross-contamination clinical samples and nosocomial infections. We investigated whether diagnostic could become contaminated the environment by running dummy sample carrying out a patient-throughput analysis. A total 29 748 patients attended clinics over year. Of these, 2860 (9.6%) had positive test result.(1) run (60 urine 10...

<h3>Background/introduction</h3> Sexualised substance use (chemsex) is an emergent phenomenon amongst some gay, bisexual and other men who have sex with (GBMSM). <h3>Aim(s)/objectives</h3> To describe patterns of chemsex clinical characteristics GBMSM attending two London sexual health clinics. <h3>Methods</h3> Retrospective case-notes review. Data on demographics, practices, behaviour, STI diagnoses HIV status extracted from a new holistic standardised profoma used in clinics June to...

It has long been recognized that sexually transmitted diseases (STDs) may occur concurrently hence necessitating screening in individuals attending Genito-Urinary Medicine (GUM) clinics. However there are few data on with more than one concurrent STD. Individuals the GUM Department Royal Infirmary of Edinburgh between 1990 and 1994 diagnosis HIV infection, genital warts, herpes, non-specific infection (NSGI), gonorrhoea syphilis were included study. A multivariate comparison was made those...