Yi Chen

ORCID: 0000-0001-9989-2165
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Research Areas
  • Bat Biology and Ecology Studies
  • Wildlife Ecology and Conservation
  • Climate change impacts on agriculture
  • Neuroendocrine regulation and behavior
  • Viral Infections and Vectors
  • Animal Vocal Communication and Behavior
  • Stress Responses and Cortisol
  • Animal Behavior and Reproduction
  • Proteoglycans and glycosaminoglycans research
  • Plant responses to elevated CO2
  • Genetic Mapping and Diversity in Plants and Animals
  • Soil Carbon and Nitrogen Dynamics
  • Liver Disease Diagnosis and Treatment
  • Microbial Metabolism and Applications
  • Meat and Animal Product Quality
  • Adipose Tissue and Metabolism
  • Child and Animal Learning Development
  • Traditional Chinese Medicine Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Plant Water Relations and Carbon Dynamics
  • Nerve injury and regeneration
  • Language and cultural evolution
  • Genetic Associations and Epidemiology
  • Plant and Fungal Interactions Research
  • Peptidase Inhibition and Analysis

Nanjing University of Chinese Medicine
2025

Nanjing Drum Tower Hospital
2025

Institute of Zoology
2019-2024

Shanghai Sixth People's Hospital
2024

Shanghai Jiao Tong University
2024

Imaging Center
2024

Academy of Military Medical Sciences
2024

Institute of Geographic Sciences and Natural Resources Research
2018-2024

Chinese Academy of Sciences
2002-2024

Central South University of Forestry and Technology
2022-2024

Multiteam digital creativity (MTDC) is a new domain of study that fits the developments era, thus scholars have called for exploring MTDC in fine-graining phase. This paper responds to this call, and adopts two studies cross-validation analysis explore theoretical framework impact factors transition Study 1 qualitative method rooted theory more comprehensive factor maximize theory’s saturation. 2 CL-WG DEMATEL method, one group decision-making optimized concept lattice, which could analyze...

10.3389/fpsyg.2023.1102085 article EN cc-by Frontiers in Psychology 2023-02-24

The naturally occurring prokaryotic CRISPR-Cas systems provide valuable resources for the development of new genome-editing tools. However, majority Cas nucleases exhibit poor editing efficiency in mammalian cells, which significantly limits their utility. Here, we have developed a method termed Improving Editing Activity by Synergistic Engineering (MIDAS). This exerts synergistic effect to improve wide range enhancing interactions between nuclease with protospacer adjacent motif (PAM) and...

10.1016/j.xinn.2022.100264 article EN cc-by-nc-nd The Innovation 2022-05-26

Most marine bacteria produce exopolysaccharides (EPS), and bacterial EPS represent an important source of dissolved organic carbon in ecosystems. It was proposed that rich uronic acid is resistant to mineralization by microbes thus has a long residence time global oceans. To confirm this hypothesis, galacturonic isolated from Alteromonas sp. JL2810. The used amend natural seawater investigate the bioavailability native populations, presence absence ammonium phosphate amendment. data...

10.1371/journal.pone.0142690 article EN cc-by PLoS ONE 2015-11-16

Astragalus membranaceus var. mongholicus (AMM), a member of the Leguminosae, is one most important medicinal plants worldwide. The dried roots AMM have wide range pharmacological effects and are traditional Chinese medicine. Here, we report first chromosome-level reference genome AMM, comprising nine pseudochromosomes with total size 1.47 Gb 27 868 protein-encoding genes. Comparative genomic analysis reveals that has not experienced an independent whole-genome duplication (WGD) event after...

10.1016/j.xplc.2022.100469 article EN cc-by-nc-nd Plant Communications 2022-10-28

Abstract Human‐gray wolf conflict over livestock depredation and absence of mitigation measures is a key threat leading to the decline populations in Pakistan, where gray wolves are endangered. In this study, we collected data from January 2019 September 2021, human–wolf were investigated by interviews with 200 shepherds that randomly selected 43 different human settlements. We used binary logistic GLM models predict landscape features related patterns. Over 3 years was responsible for 963...

10.1002/wll2.12031 article EN cc-by Wildlife Letters 2024-03-01

Depression is commonly associated with gastrointestinal (GI) disorders, such as constipation, which can potentially intensify depressive symptoms. The interplay between these conditions believed to be facilitated by the gut-brain axis, suggests a complex bidirectional interaction. Current treatments, antidepressants and prokinetics, are often side effects high recurrence rates, highlighting need for effective treatments targeting both depression constipation. This study was designed assess...

10.1016/j.brainresbull.2025.111207 article EN cc-by Brain Research Bulletin 2025-01-14

Significance Speech and bipedalism are key aspects of behavior that emerged during human evolution. FOXP2 , a gene implicated in speech language disorder, has been suggested to contribute Here, through knockout studies mouse Foxp2 we show this is not only important for neural circuits involved vocal behaviors, it also helps regulate relevant anatomical substrates. We additionally demonstrate influences skeletal features may be bipedal locomotion. Our findings raise the possibility might...

10.1073/pnas.1721820115 article EN Proceedings of the National Academy of Sciences 2018-08-13

Abstract Chilling stress has become a major limiting factor that reduces crop productivity worldwide. In this study, we identified new gene bHLH57 , whose product enhances chilling tolerance in rice at diverse developmental stages. was mainly expressed leaves and anthers, its protein targeted to the nucleus. Overexpression of enhanced by increasing trehalose synthesis, whereas mutants CRISPR/Cas9‐mediated mutagenesis were more sensitive had reduced trehalose. Meanwhile, may regulate ROS...

10.1111/pce.14513 article EN Plant Cell & Environment 2022-12-13

Many studies have demonstrated the remarkable potential of assimilating remotely sensing leaf area index (LAI) products into crop models in estimating regional yield. To ensure temporal consistency between and remote-sensing system, it is prerequisite to derive phenology information from LAI products. However, previous mainly detected through vegetation (VI). Although some pieces research applied monitoring for trees shrubs, fewer focused on crops, especially those with two or three growing...

10.1080/01431161.2018.1460504 article EN International Journal of Remote Sensing 2018-04-09

1. Morphological characteristics, especially coloration, are related to thermoregulation and camouflage, both of which crucial for species survival fitness. In cool environments such as the understorey closed rainforests, darker organisms have thermal advantages may be able absorb heat more efficiently. However, habitats also suitable with respect making it difficult elucidate whether association dark‐coloured shady is a consequence stress or predation pressure, both. 2. this study,...

10.1111/een.12499 article EN Ecological Entomology 2018-01-02

Epidemiologic reports suggest that the most severe or fatal adenoviral disease in children might be associated with human adenovirus (HAdV) type 7. However, pathogenesis of HAdV-7-induced remains poorly understood.HAdV-3 and HAdV-7 replication kinetics host response to infection were compared using ex vivo lung tissue cultures. Furthermore, cytokine chemokine levels presence DNA serum hospitalized infected (n = 65) HAdV-3 48) measured (using a multiplex immunoassay Taqman real-time...

10.1093/infdis/jiaa524 article EN The Journal of Infectious Diseases 2020-08-14

This study aims to explore biomarkers associated with vitiligo and analyze the pathological role of immune cell infiltration in disease. We used robust rank aggregation (RRA) method integrate three data sets downloaded from gene expression omnibus database, identify differentially expressed genes (DEGs) functional correlation. Then, comprehensive strategy combined weighted coexpression network analysis (WGCNA) logical regression selection operator (LASSO), support vector machine recursive...

10.1080/21655979.2021.1933743 article EN Bioengineered 2021-01-01

Abstract Background Serum biochemical indicators are often regarded as direct reflections of animal metabolism and health. The molecular mechanisms underlying serum chicken (Gallus Gallus) have not been elucidated. Herein, we performed a genome-wide association study (GWAS) to identify the variation associated with indicators. aim this research was broaden understanding in chickens. Results A GWAS carried out on 734 samples from an F2 Gushi× Anka population. All chickens were genotyped by...

10.1186/s12864-023-09206-7 article EN cc-by BMC Genomics 2023-03-02

This paper deals with studies on the use of Zn(II)-L-ornithine complex as a chiral selecting system for enantioseparation and UV detection amino acids (AAs) by using principle ligand-exchange CE. Successful three pairs label-free aromatic AAs four labeled AA enantiomers have been achieved buffer 100.0 mM boric acid, 5.0 ammonium acetate, 3.0 ZnSO4 6.0 L-Orn at pH 8.2. new method was shown to be applicable quantitative analysis D- L-aromatic AAs, linear range between 12.5 800.0 microg/mL,...

10.1002/elps.200800623 article EN Electrophoresis 2009-06-30

Paeoniflorin, an organic compound extracted from the roots of white peony (Paeonia lactiflora) plant, has previously been shown to exert antidepression and prokinetic effects. The traditional Chinese prescription Si-Ni-San, which paeoniflorin is a constituent, often used in treating depression functional gastrointestinal disorders. effectiveness Si-Ni-San be less effective paeoniflorin-deleted form. present study further investigates whether alone as herbal prescriptions specifically any...

10.1155/2020/2153571 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01
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