- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Cerebral Venous Sinus Thrombosis
- Ocular Surface and Contact Lens
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Mast cells and histamine
- melanin and skin pigmentation
- COVID-19 Clinical Research Studies
- Artificial Intelligence in Healthcare and Education
- Optical Coherence Tomography Applications
- Ocular Disorders and Treatments
- Hematological disorders and diagnostics
- Vascular Malformations and Hemangiomas
- Protein Tyrosine Phosphatases
- Ophthalmology and Visual Health Research
- Medical Imaging and Pathology Studies
- Dermatologic Treatments and Research
Agostino Gemelli University Polyclinic
2020-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
Università Cattolica del Sacro Cuore
2020-2025
Hôpital Intercommunal de Créteil
2022-2024
Vita-Salute San Raffaele University
2022-2024
Université Paris-Est Créteil
2023-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022-2024
Paris-Est Sup
2023-2024
University of Brescia
2024
IRCCS Ospedale San Raffaele
2023
We aimed to define the capability of three different publicly available large language models, Chat Generative Pretrained Transformer (ChatGPT-3.5), ChatGPT-4 and Google Gemini in analysing retinal detachment cases suggesting best possible surgical planning.
The ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2's) to cause multi-organ ischemia and coronavirus-induced posterior segment eye diseases in mammals gave concern about potential sight-threatening post disease 2019 patients. radial peripapillary capillary plexus (RPCP) is a sensitive target due the important role vascular supply retinal nerve fiber layer (RNFL). Eighty patients one month after SARS-CoV-2 infection 30 healthy were selected undergo structural OCT...
Systemic vascular involvement in COVID-19 has been identified several patients: not only endothelial derangement and increased permeability are reported to be early hallmarks of organ damage patients with but also the most important cause worsening clinical conditions severe cases SARS-CoV-2 infection. There reasons hypothesize that eye, retina particular, could a target infection.This cohort observational study analyzes OCT angiography structural 70 post-COVID-19 evaluated at 1-month...
Age related macular degeneration (AMD) represents a leading cause of vision loss and it is expected to affect 288 million people by 2040. During the last decade, machine learning technologies have shown great potential revolutionize clinical management AMD support research for better understanding disease. The aim this review provide panoramic description all applications AI screening that been analyzed in recent past literature. Deep (DL) can be effectively used diagnose AMD, predict short...
To predict improvement of best-corrected visual acuity (BCVA) 1 year after pars plana vitrectomy for epiretinal membrane (ERM) using artificial intelligence methods on optical coherence tomography B-scan images.Four hundred and eleven (411) patients with Stage II ERM were divided in a group (IM) (≥15 ETDRS letters VA recovery) no (N-IM) (<15 letters) according to 1-year 25-G internal limiting peeling. Primary outcome was the creation deep learning classifier (DLC) based images prediction....
Purpose To evaluate the differences between two distinct patient postoperative positions following rhegmatogenous macula-off retinal detachment surgery. Methods In this consecutive clinical study, 26 patients were placed in either face-up or face-down position group. Postoperative follow-ups conducted at 1, 3, and 6 months using type 1 M-CHARTS, best-corrected visual acuity (BCVA), intraocular pressure, optical coherence tomography imaging to functional anatomical outcomes after Results The...
Costello syndrome (CS) is an ultra-rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which involved in ocular development and some eye pathologies. However, only few studies assessing ophthalmic features individuals with CS are available. In this article, we describe main anomalies MRI findings large cohort patients compare our data theliterature. 21 were enrolled performedvisual acuity refractive error assessment,...
This is a cohort study to evaluate the presence of objective signs and subjective symptoms dry eye disease in postcoronavirus 2019 (COVID-19) patients compared with control.Prospective, observational, single-ctenter, study. Sixty-four post-COVID-19 50 control were recruited. All participants underwent complete ophthalmological examination including Ocular Surface Disease Index Questionnaire (OSDI), best-corrected visual acuity, slit-lamp biomicroscopy, fundus examination, Schirmer test type...
To evaluate the safety of subretinal injection cord blood platelet-rich plasma (CB-PRP) and its possible effect in eyes affected by geographic atrophy (GA) associated with dry age-related macular degeneration (d-AMD).
Initial stages of Best vitelliform macular dystrophy (BVMD) and adult (AVMD) harbor similar blue autofluorescence (BAF) optical coherence tomography (OCT) features. Nevertheless, BVMD is characterized by a worse final stage visual acuity (VA) an earlier onset critical VA loss. Currently, differential diagnosis requires invasive time-consuming process including genetic testing, electrooculography (EOG), full field electroretinogram (ERG), testing. The aim our study was to automatically...
To evaluate visual acuity and morphologic changes after photobiomodulation (PBM) for patients affected with large soft drusen and/or drusenoid pigment epithelial detachment associated dry age-related macular degeneration.Twenty eyes degeneration were included treated using the LumiThera Valeda Light Delivery System. All underwent two treatments per week 5 weeks. Outcome measures best-corrected acuity, microperimetry-scotopic testing, volume, central thickness, quality of life score at...
Purpose: Radial keratotomies (RKs) are responsible for corneal irregularities resulting in biometric errors and lower best-corrected visual acuity (BCVA) due to lower-order higher-order optical aberrations. The aim of the study was compare performances new old generation formulas a population RK patients. Methods: patients who underwent phacoemulsification with intraocular lens (IOL) implantation were retrospectively recruited. Inclusion criteria availability preoperative 6-month...
Abstract Purpose: To identify salient imaging features to support human-based differential diagnosis between subretinal hemorrhage(SH) due choroidal neovascularization(CNV)onset and SH without CNV (simple bleeding,SB)in pathologic myopia eyes using a machine learning(ML)-based stepwise approach. Materials methods: Four different methods for feature extraction were applied:GradCAM visualization,reverse engineering,image processing human graders' measurements.GradCAM was performed on deep...
To evaluate the incidence, rate, and pattern of progression myopic maculopathy in eyes operated with macular buckle (MB) for traction versus a control group without surgery to find out whether varies due MB's indentation possible MB-related pigmentary changes or atrophy.
To assess feasibility of automatic segmentation OCT biomarkers visual acuity (VA) and the possibility prediction postoperative VA after successful reattachment in macula off rhegmatogenous retinal detachment (RRD) eyes using artificial intelligence (AI). retrospective case control study Patients operated pars plana vitrectomy (PPV) for macula-off non-traumatic RRD with available good quality acquisitions were included. Ellipsoid zone(EZ) foveal damage reflectivity, external limiting...
Purpose: To assess the diagnostic capabilities of most recent chatbots releases, GPT-4o and Gemini Advanced, facing different retinal diseases. Methods: Exploratory analysis on 50 cases with surgical (n=27) medical (n=23) pathologies, whose optical coherence tomography/angiography (OCT/OCTA) scans were dragged into ChatGPT Gemini’s interfaces. Then, we asked “Please describe this image” classified diagnosis as: 1) Correct; 2) Partially correct; 3) Wrong; 4) Unable to exam type 5) Diagnosis...
The purpose of this study was to compare the performances infrared (IR), fundus autofluorescence (FAF), and multicolor (MC) imaging in characterization geographic atrophy, with a focus on possibility detect incomplete retinal pigmented outer atrophy (iRORA) en face imaging.The ground truth established by two graders evaluating spectral-domain optical coherence tomography (SD-OCT) images. A score for visibility foveal sparing margins attributed. Measurement atrophic area fovea-to-margin...
Abstract Purpose The aim this study is to determine anterior chamber parameters variations induced by PreserFlo MicroShunt implantation, in the early post-operative days. Methods This a prospective observational on 48 eyes undergoing implantation alone ( n = 30) or combined with phacoemulsification 18). Anterior depth (ACD) and volume (ACV), central corneal thickness (CCT) total astigmatism (TCA) were evaluated pre-operatively, post-operatively at day-1 1 week Pentacam tomography. Results...