Optical coherence tomography angiography is a novel and noninvasive technique for imaging retinal microvasculature by detecting changes in reflectivity that related to blood flow. The purpose of this study was describe Type 2 neovascularization characteristics age-related macular degeneration using optical angiography.Fourteen eyes 14 consecutive patients with were prospectively included. All underwent complete ophthalmological examination, including color infrared fundus photography,...

Purpose . To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them those obtained multimodal imaging. Methods A series of consecutive patients diagnosed CSC, underwent OCTA imaging, including spectral domain OCT, fluorescein, indocyanine green angiography. images were performed at three main depth intervals: automatically segmented outer retina, manually adjusted choriocapillaris. Results Thirty-three 32...

To report the imaging features of subretinal fibrosis secondary to exudative age-related macular degeneration (AMD) on optical coherence tomography angiography.All consecutive patients diagnosed with complicating AMD were imaged by color retinal photographs or multicolor imaging, fluorescein angiography, spectral domain tomography, and angiography. Eyes active observed during last 6 months compared those without any sign exudation >6 months.Forty-nine eyes 47 included. A blood flow inside...

<h3>Purpose</h3> To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A). <h3>Methods</h3> Prospective study with consecutive patients affected PCV were included. All underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green spectral-domain OCT and OCT-A. <h3>Results</h3> Twelve eyes 12 (mean age 72.6±10.5 years; 4 men 8 women) included for...

To analyze the main characteristics and outcome of polyarteritis nodosa (PAN)-type vasculitis associated with hepatitis C virus (HCV).We reported 31 patients chronically infected HCV who satisfied American College Rheumatology Chapel Hill criteria for PAN, seen between 1990 2009 in a university center.Among cohort 161 HCV-related vasculitis, (19.3%) were diagnosed as having PAN. The median age was 64.5 years (interquartile range 49.5-70.5 years), 54.8% women. Compared HCV-associated mixed...

In Brief Purpose: To report the imaging features of Type 3 neovascularization secondary to exudative age-related macular degeneration on optical coherence tomography angiography (OCTA). Methods: All consecutive treatment-naive patients diagnosed with early-stage underwent by color retinal photographs or multicolor imaging, fluorescein angiography, indocyanine green spectral domain tomography, and OCTA. The OCTA were analyzed correlated findings conventional tomography. Results: A total 18...

To suggest a clinical distinction between idiopathic polypoidal choroidal vasculopathy (PCV) and secondary polyps associated with neovascular age-related macular degeneration (NV-AMD).The study was retrospective case series of 52 eyes consecutive patients (31 females 21 males) diagnosed PCV. Initial diagnosis based on scanning laser ophthalmoscope-indocyanine green angiography (SLO-ICGA) in association fluorescein (FA) optical coherence tomography (OCT). All the data images were analyzed...

To describe the qualitative and quantitative changes in choroidal neovascularization (CNV) flow pattern after anti-vascular endothelial growth factor therapy, by optical coherence tomography angiography (OCTA).Consecutive patients with neovascular age-related macular degeneration underwent multimodal imaging, including OCTA at initial examination last visit. High-flow networks choriocapillaris segmentation of were qualitatively quantitatively analyzed baseline follow-up, to characterize...

To describe the optical coherence tomography angiography (OCTA) characteristics of active myopic choroidal neovascularization (CNV) and to compare its sensitivity versus fluorescein spectral-domain tomography.Consecutive highly patients complicated with CNV were prospectively included. The OCTA features analyzed correlated findings conventional imaging (spectral-domain angiography).Twenty eyes 19 (mean age: 59.6 ± 12.1 years, mean spherical equivalent: -13.5 3.6 diopters) presenting both...

Background. In recent years, deep learning has been increasingly applied to a vast array of ophthalmological diseases. Inherited retinal diseases (IRD) are rare genetic conditions with distinctive phenotype on fundus autofluorescence imaging (FAF). Our purpose was automatically classify different IRDs by means FAF images using algorithm. Methods. this study, patients retinitis pigmentosa (RP), Best disease (BD), Stargardt (STGD), as well healthy comparable group were used train multilayer...

To evaluate the capacity of OCT angiography (OCTA) for detecting infraclinical lesions in parafoveal capillaries diabetic patients without retinopathy (DR).This prospective observational cross-sectional case-control study analyzed superficial and deep capillary plexuses (SCP DCP) on macular OCTA scans (3 × 3 mm) centered fovea. We compared 22 (34 eyes included) DR diagnosis color fundus photographs, with age- gender-matched nondiabetic controls (40 included). Qualitative analysis concerned...

To study the efficacy of intravitreal injection (IVI) dexamethasone implant as second-line treatment in patients with resistant chronic diabetic macular edema nonresponsive to 6 monthly consecutive IVI ranibizumab.A retrospective was conducted over 9 months. Best-corrected visual acuity and central thickness were noted. Patients best-corrected ≤20/40 using Snellen chart, ≥300 μm, poor response ranibizumab included. received examined at 1, 3, 6, months.Thirteen eyes 12 included (6 men women;...

To investigate the morphologic changes on optical coherence tomography angiography (OCTA) of treatment-naive Type 3 neovascularization secondary to exudative age-related macular degeneration after 1 year anti-vascular endothelial growth factor therapy.Consecutive patients diagnosed with early-stage were enrolled in this retrospective study. All underwent color fundus photographs/MultiColor (Heidelberg Engineering) imaging, fluorescein angiography, indocyanine green structural spectral domain...

To evaluate the outer retinal layer (ellipsoid zone [EZ] and external limiting membrane [ELM]) changes following intravitreal aflibercept injections in eyes with treatment-naïve exudative age-related macular degeneration (eAMD) to correlate these fluid response visual improvement.A retrospective case series of 50 eAMD followed-up for 18 months. All patients underwent regular comprehensive ophthalmic examinations. The presence EZ disruption, ELM swelling, subretinal hyper-reflective exudation...

Purpose: To assess the variations induced by exercise in retinal vascular density (VD), foveal avascular zone (FAZ) area, and fractal dimension (FD) at superficial (SCP) deep (DCP) capillary plexa healthy subjects means of optical coherence tomography angiography (OCT-A). Methods: Consecutive were prospectively included into two groups, ranging age from 18 to 29 years for group 1 30 40 2. Data 3 × 3-mm OCT-A acquisition centered on macula SCP DCP (VD, FAZ FD), heart rate, systolic-diastolic...

Purpose. To compare the qualitative and quantitative choroidal neovascularization (CNV) changes after antivascular endothelial growth factor (anti-VEGF) therapy in treatment-naïve treated eyes with age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods. Consecutive patients neovascular AMD underwent multimodal imaging, including OCTA (AngioPlex, CIRRUS HD-OCT model 5000; Carl Zeiss Meditec, Inc., Dublin, OH) at baseline three monthly follow-up...

Purpose The prognosis of people infected with Fungi especially immunocompromised depends on rapid and accurate diagnosis to capitalize time administration specific treatments. However, cultures produce false negative results nucleic-acid amplification techniques require complex post-amplification procedures differentiate relevant fungal types. objective this work was develop a new diagnostic strategy based real-time polymerase-chain reaction high-resolution melting analysis (PCR-HRM) that a)...