A5071060813- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Optical Coherence Tomography Applications
- Ophthalmology and Visual Impairment Studies
- melanin and skin pigmentation
- Ocular and Laser Science Research
- Intracranial Aneurysms: Treatment and Complications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Vasculitis and related conditions
- Vascular Malformations Diagnosis and Treatment
- Drug-Induced Ocular Toxicity
- Tuberous Sclerosis Complex Research
- Sarcoidosis and Beryllium Toxicity Research
- Saffron Plant Research Studies
- Cardiovascular Syncope and Autonomic Disorders
- Cerebral Venous Sinus Thrombosis
- Traumatic Ocular and Foreign Body Injuries
- Esophageal and GI Pathology
- Cardiovascular Health and Disease Prevention
- Retinopathy of Prematurity Studies
Hôpital Intercommunal de Créteil
2013-2021
Sorbonne Université
2012-2021
Université Paris-Est Créteil
2013-2021
Pitié-Salpêtrière Hospital
2021
Inserm
2020
Paris-Est Sup
2020
Centre hospitalier national d'ophtalmologie des Quinze-Vingts
2020
Hôpital Lariboisière
2016
Novartis (France)
2016
Sorbonne Paris Cité
2016
To study the relationship between location of cystoid spaces and retinal capillary nonperfusion areas in diabetic macular edema (DCME).In this retrospective study, 24 eyes 21 patients with chronic DCME were followed using optical coherence tomography angiography. The density superficial plexus deep was measured AngioAnalytics software all 20 healthy controls. Diabetic improved spontaneously or after treatment 11 eyes.The intraretinal surrounded by capillary-flow void 71% cases 96% cases. had...
Purpose: To assess the variations induced by exercise in retinal vascular density (VD), foveal avascular zone (FAZ) area, and fractal dimension (FD) at superficial (SCP) deep (DCP) capillary plexa healthy subjects means of optical coherence tomography angiography (OCT-A). Methods: Consecutive were prospectively included into two groups, ranging age from 18 to 29 years for group 1 30 40 2. Data 3 × 3-mm OCT-A acquisition centered on macula SCP DCP (VD, FAZ FD), heart rate, systolic-diastolic...
Purpose. To compare the qualitative and quantitative choroidal neovascularization (CNV) changes after antivascular endothelial growth factor (anti-VEGF) therapy in treatment-naïve treated eyes with age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods. Consecutive patients neovascular AMD underwent multimodal imaging, including OCTA (AngioPlex, CIRRUS HD-OCT model 5000; Carl Zeiss Meditec, Inc., Dublin, OH) at baseline three monthly follow-up...
BACKGROUND AND OBJECTIVE: To compare capillary density (CD) changes assessed by optical coherence tomography angiography (OCTA) during diabetic retinopathy (DR) progression using three previously published methods: binarization, skeletonization, and automated flow (AFD). PATIENTS METHODS: Retrospective study of 98 eyes 74 patients with diabetes 18 control imaged OCTA. The macular CD at each stage DR was the methods were compared to eyes. RESULTS: AFD only method that detected differences...
To investigate the appearance of medium-large drusen and reticular pseudodrusen on adaptive optics (AO).In 14 consecutive patients, AO infrared (IR) images were overlaid with confocal scanning-laser-ophthalmoscope IR reflectance IR-referenced spectral-domain optical coherence tomography.In eight eyes six a total 19 investigated by imaging. En face revealed as highly hyper-reflective round/oval lesions, always centred and/or surrounded continuous/discontinuous hyporeflectivity. Cone...
To describe adaptive optics (AO) imaging of foveal sparing in geographic atrophy (GA) secondary to age-related macular degeneration.Flood-illumination AO infrared (IR) fundus images were obtained four consecutive patients with GA using an retinal camera (rtx1; Imagine Eyes). Adaptive IR overlaid confocal scanning laser ophthalmoscope near-IR autofluorescence allow direct correlation en face features areas sparing. appearance and sparing, preservation functional photoreceptors, cone densities...
To describe focal scleral ectasia in areas of macular/perimacular patchy chorioretinal atrophy secondary to pathologic myopia.Thirty-nine consecutive patients with myopia and at least one eye, without ectasia, were analyzed by infrared reflectance (IR) and/or multicolor imaging, enhanced depth imaging optical coherence tomography (EDI-OCT) (39 patients, 78 eyes), swept source (SS)-OCT (13 out 39 26 eyes) cross-sectional scan.Focal was found 12 68 eyes (11 27 females/12 males; mean age 65.7 ±...
Purpose: To report intraretinal hyperreflective lines related to various macular conditions. Methods: All cases were imaged with color photographs, autofluorescence images, and spectral-domain optical coherence tomography, some fluorescein and/or indocyanine green angiography. Demographic data, imaging, course outcome retrospectively analyzed. Results: Forty-nine eyes of 43 patients (16 men 27 women) included. Hyperreflective vertical (38 eyes) or curvilinear along the Henle fiber layer (11...
We aimed to evaluate the anatomical and functional outcome of selective photocoagulation idiopathic macular telangiectasia type 1 by navigated focal laser (Navilas, OD-OS GmBH). Consecutive patients with were included in analysis. All treated laser, planned on multimodal imaging. Seven eyes seven retrospectively analyzed. Navigated successfully occluded microaneurysms, inducing regression edema exudation, significative improvement best-corrected visual acuity at 3 (
There is no widely accepted treatment for persistent/chronic central serous chorioretinopathy. The present study aimed to evaluate the efficacy, safety, and factors associated response navigated micropulse laser in chorioretinopathy.Retrospective observational case series including consecutive patients presenting with symptomatic persistent chronic All were treated 5% Navilas system (Navilas®, OD-OS GmBH, Teltwo, Germany), by overlying fluorescein angiography, indocyanine green angiography...
Purpose: To document directional reflectivity of fundus lesions in a case acute macular neuroretinopathy. Methods: Case report. Clinical and imaging data from patient with neuroretinopathy were reviewed. Imaging comprised infrared scanning laser ophthalmoscopy, optical coherence tomography flood-illumination adaptive optics images acquired through different entry pupils the cardinal directions (approximately 2° eccentricity). Results: The reported bilateral paracentral scotoma revealing...
Purpose: Macular edema is a common retinal disease which may leave important anatomical and functional sequelaes. Directional fundus imaging consists of comparing on- off-axis images to reveal angle-dependent reflectance properties structures, be related misaligned photoreceptors. Here, we analyzed directional optical coherence tomography (OCT) flood-illumination adaptive optics ophthalmoscopy detect evidence photoreceptors following macular edema. Methods: Transversal, observational study....
To evaluate the effects of Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related degeneration (AMD).Prospective case-series including nine eyes presenting with MNV persistence exudative signs, no longer responding anti-VEGF therapy, best-corrected visual acuity at least 1.3 logMar. All patients were treated overlaid (OCTA) images site branching large neovascular trunks.Occlusion trunks successfully occurred in...
To evaluate the anatomical and functional outcome of selective photocoagulation capillary macroaneurysms (CMAs) by navigated focal laser.Consecutive patients with solitary or secondary CMAs greater than 150 mm in diameter were included this analysis. All treated laser received multimodal imaging.Seventeen eyes 17 retrospectively analyzed. Navigated successfully occluded 100% CMAs, inducing significative improvement best-corrected visual acuity at 3 (P = .002) 6 months .001) a decrease...
Purpose: To evaluate vascular density (VD), fractal dimension, and skeletal on optical coherence tomography angiography in eyes with idiopathic foveal hypoplasia (IFH). Methods: Patients presenting IFH to Creteil University Eye Clinic between January 2015 October 2018 age-matched healthy controls were retrospectively evaluated. Vascular density, dimension analyses computed superficial capillary plexa (SCP) deep (DCP) images the whole image using a custom algorithm. central 1 mm 2 peripheral...
Purpose: To report a case of retinal astrocytic hamartoma imaged by optical coherence tomography angiography (OCTA), followed for 2 years. Methods: Observational report. Results: A 25-year-old woman was referred an incidental lesion in the left eye (LE). At baseline, best-corrected visual acuity LE 20/32, and fundus examination showed presence round, pigmented juxtafoveal region, corresponding, on spectral domain OCT, to hyperreflective within nerve fiber layer. Optical revealed high-flow...
To describe optical coherence tomography angiography findings at baseline and during the follow-up of choroidal neovascularization secondary to rupture (CR) in a patient with kidney transplant treated by single intravitreal injection ranibizumab.The clinical course, conventional multimodal imaging including ultra-widefield fundus color photography autofluorescence (Optos California, Marlborough, MA), spectral-domain (SD-OCT Spectralis; Heidelberg Engineering, Heidelberg, Germany),...
To report a case of choroidal neovascularization (CNV) secondary to laser injury imaged by optical coherence tomography angiography (OCTA) and treated intravitreal anti-vascular endothelial growth factor (VEGF).A 14-year-old boy presented with vision loss central scotoma in the right eye (RE) last month, after having stared at beam pointer. At presentation, his best-corrected visual acuity (BCVA) RE was 20/40 spectral-domain OCT (SD-OCT) showed an interruption ellipsoid zone presence...