A5046347482- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Atherosclerosis and Cardiovascular Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Optical Coherence Tomography Applications
- Iron Metabolism and Disorders
- Ophthalmology and Visual Impairment Studies
- Trace Elements in Health
- Drug-Induced Ocular Toxicity
- Systemic Lupus Erythematosus Research
- Social Sciences and Governance
- Neurological Complications and Syndromes
- Lysosomal Storage Disorders Research
- Retinopathy of Prematurity Studies
- Geological Modeling and Analysis
- Folate and B Vitamins Research
- Hemoglobinopathies and Related Disorders
- Retinal and Macular Surgery
- Dermatologic Treatments and Research
- Autoimmune Bullous Skin Diseases
- Skin Diseases and Diabetes
Hôpital Intercommunal de Créteil
2014-2025
Université Paris-Est Créteil
2001-2018
Centre hospitalier régional d'Orléans
2010-2015
Egis (France)
2015
Fondation Ophtalmologique Adolphe de Rothschild
2015
In Brief Purpose: To survey compliance with recommended intravitreal ranibizumab treatment protocols in daily clinical practice France, reference to outcomes. Methods: A retrospective, descriptive, observational study patients subfoveal wet age-related macular degeneration treated ranibizumab. All historical data for the period, including demographic, treatment, and disease details visual acuity measurements (baseline, Month 3, 12), were recorded retrospectively at least 12 months after...
In Brief Purpose: The purpose of this study was to compare two strategies for retreatment with ranibizumab in exudative age-related macular degeneration. Method: Two series consecutive patients treated a hospital-based department ophthalmology were analyzed retrospectively: the first (n = 52), after as-needed reinjections (PRN group) and second 38) according Inject Extend dosing method (IaE group). Patients' baseline characteristics, type choroidal neovascularization, Early Treatment...
Optical coherence tomography angiography is a novel and noninvasive technique for imaging retinal microvasculature by detecting changes in reflectivity that related to blood flow. The purpose of this study was describe Type 2 neovascularization characteristics age-related macular degeneration using optical angiography.Fourteen eyes 14 consecutive patients with were prospectively included. All underwent complete ophthalmological examination, including color infrared fundus photography,...
Purpose . To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them those obtained multimodal imaging. Methods A series of consecutive patients diagnosed CSC, underwent OCTA imaging, including spectral domain OCT, fluorescein, indocyanine green angiography. images were performed at three main depth intervals: automatically segmented outer retina, manually adjusted choriocapillaris. Results Thirty-three 32...
To report the imaging features of subretinal fibrosis secondary to exudative age-related macular degeneration (AMD) on optical coherence tomography angiography.All consecutive patients diagnosed with complicating AMD were imaged by color retinal photographs or multicolor imaging, fluorescein angiography, spectral domain tomography, and angiography. Eyes active observed during last 6 months compared those without any sign exudation >6 months.Forty-nine eyes 47 included. A blood flow inside...
In Brief Purpose: The real-life LUMIERE study on patients with wet age-related macular degeneration treated intravitreal ranibizumab in 2006 to 2009 showed that failure follow recommendations was associated lower efficacy than had been observed the development phase. TWIN Study reviewed situation 2010 2011. Methods: Retrospective, descriptive purely observational of data acquired after 12 months treatment ranibizumab. Results: 881 (68% women, mean age, 79 years) by 21 ophthalmologists, gain...
To identify the causes of loss vision after ranibizumab therapy in patients with exudative age-related macular degeneration treated three clinical settings.A retrospective multicentric analysis 290 consecutive eyes comprising cohorts from 3 settings showed that 21 lost ≥ 15 letters on Early Treatment Diabetic Retinopathy Study chart 1 year start treatment. Fundus images these were analyzed by two independent readers to investigate visual loss. The compared. A search was made for factors...
We observed hyperreflective dome-shaped or pyramidal structures (HPS) on spectral domain optical coherence tomography (SD-OCT) in patients affected with geographic atrophy (GA). Our purpose was to describe the multimodal imaging features of HPS identified areas GA age-related macular degeneration.This is a retrospective case series harboring atrophic areas. Multimodal examination including infrared reflectance, fundus autofluorescence, and SD-OCT, performed for each patient. Infrared...
Purpose. To compare the qualitative and quantitative choroidal neovascularization (CNV) changes after antivascular endothelial growth factor (anti-VEGF) therapy in treatment-naïve treated eyes with age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods. Consecutive patients neovascular AMD underwent multimodal imaging, including OCTA (AngioPlex, CIRRUS HD-OCT model 5000; Carl Zeiss Meditec, Inc., Dublin, OH) at baseline three monthly follow-up...
EMAP (Extensive Macular Atrophy with Pseudodrusen) is a maculopathy we recently described that shares pseudodrusen and geographic atrophy Age-related Disease (AMD). differs from AMD by an earlier age of onset (50-55 years) characteristic natural history comprising night blindness followed severe visual loss. In prospective case-control study, ten referral centers included 115 (70 women, 45 men) patients 345 matched controls to appraise dietary, environmental, genetic risk factors. The...
To describe the phenotype and genotype of a 10-year-old boy affected with enhanced S-cone syndrome associated neovascularization.Fundus autofluorescence, fluorescein angiography, indocyanine green spectral domain optical coherence tomography, full-field electroretinogram NR2E3 molecular testing were performed.Best-corrected visual acuity was measured as 20/32, right eye 20/20, left eye. Fluorescein angiographies showed unilateral macular retinochoroidal anastomosis on his eye, tomography...
To describe unusual retinal findings of a patient affected by hemochromatosis.Case report 49-year-old who presented progressive loss vision. Fundus photography, fluorescein angiography, full-field electroretinogram, autofluorescence imaging, and spectral domain optical coherence tomography were performed. The was known to be homozygous for the C282Y mutation in HFE gene.Visual acuity measured at 20/20 on his right eye 20/25 left eye. Retinal imaging showed alterations pigment epithelium...
Abstract APOLLON (NCT02924311) was a prospective observational study to evaluate the effectiveness of intravitreal aflibercept (IVT-AFL) treatment diabetic macular edema (DME) over 24 months in routine clinical practice France. The primary endpoint mean change from baseline best-corrected visual acuity (BCVA; Early Treatment Diabetic Retinopathy Study letters) by 12 months, and safety monitored throughout study. Of 402 patients enrolled across 61 participating clinics hospitals France, 168...
Purpose: To describe the management of active choroidal neovascularization (CNV) during pregnancy with use a dexamethasone intravitreal implant (DXI) (Ozurdex). Methods: Case series CNV treated DXI at least 12-month follow-up retrospectively analyzed 2 high-volume referral centers in France. Medical records and multimodal macular imaging were evaluated. Results: Three eyes 3 patients (age 30.0 ± 3.6 years) included. One case idiopathic two cases secondary to multifocal choroiditis analyzed....
The purpose of this study is to evaluate real-world treatment outcomes in patients with neovascular age-related macular degeneration (nAMD) treated intravitreal aflibercept (IVT-AFL) routine clinical practice France.RAINBOW (NCT02279537) was an ambispective, observational, 4-year assessing IVT-AFL effectiveness, patterns, and safety nAMD France. Treatment-naïve prescribed according local (pro re nata or treat-and-extend) were eligible. Three cohorts retrospectively identified based on their...
Purpose: The last decade has seen many improvements in the imaging of choroids, retina, and vitreous. However, there are no available data about changes practice retina units. present study was therefore undertaken to document 12-year this units France, particularly relative distribution different methods. Methods: This retrospective performed 4 considered be representative France. They comprise 2 departments ophthalmology university-based hospitals Paris Nantes, one a non-university-based...