- Hepatitis C virus research
- Systemic Lupus Erythematosus Research
- Vasculitis and related conditions
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Ocular Diseases and Behçet’s Syndrome
- Chronic Lymphocytic Leukemia Research
- Renal Diseases and Glomerulopathies
- Sarcoidosis and Beryllium Toxicity Research
- Retinal and Optic Conditions
- Liver Diseases and Immunity
- Heparin-Induced Thrombocytopenia and Thrombosis
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Eosinophilic Disorders and Syndromes
- Liver Disease and Transplantation
- Diabetes and associated disorders
- Atherosclerosis and Cardiovascular Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Otitis Media and Relapsing Polychondritis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Systemic Sclerosis and Related Diseases
- Salivary Gland Disorders and Functions
- Immunodeficiency and Autoimmune Disorders
Pitié-Salpêtrière Hospital
2016-2025
Sorbonne Université
2016-2025
Assistance Publique – Hôpitaux de Paris
2016-2025
Inserm
2016-2025
Centre de Référence des Maladies Autoinflammatoires et des Amyloses
2018-2025
Bipar
2008-2024
Université Paris Cité
2014-2024
Centre National de la Recherche Scientifique
2015-2024
Centre de Recherche sur l'Inflammation
2024
Université de Montpellier
2024
Dual antiplatelet therapy with clopidogrel plus low-dose aspirin has not been studied in a broad population of patients at high risk for atherothrombotic events.
Some epidemiologic studies suggest a link between hepatitis C virus (HCV) infection and some B-cell non-Hodgkin's lymphomas. We undertook this study after patient with splenic lymphoma villous lymphocytes had hematologic response antiviral treatment of HCV infection.
Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced levels of regulatory T cells (Tregs). Resolution HCV infection correlates cure and recovery Treg levels. We reasoned that interleukin-2, a cytokine promotes survival function, could be beneficial for patients is resistant to therapy.
To assess the prevalence of clinical and biologic extrahepatic manifestations hepatitis C virus (HCV) infection to identify associations between manifestations.To analyze natural history HCV infection, we reviewed only data recorded prospectively during first visit 1,614 patients with chronic coming from a single monocenter cohort. Exclusion criteria were positivity for B surface antigen or human immunodeficiency virus. The dermatologic, rheumatologic, neurologic, nephrologic manifestations;...
To determine factors associated with COVID-19-related death in people rheumatic diseases.
Cacoub, Patrice M.D.; Renou, Christophe Rosenthal, Eric Cohen, Pascal Loury, Isabelle Loustaud-Ratti, Véronique Yamamoto, Ana-Maria Camproux, Anne-Claude Ph.D.; Hausfater, Pierre Musset, Lucile Veyssier, Raguin, Gilles Piette, Jean-Charles Germmc, for the Author Information
Introduction A panel of experts met in Paris on 18 April to present research and practice protocols, discuss topics current interest related the treatment HIV/hepatitis C virus (HCV) co-infection. The information presented focussed following main aspects: magnitude problem HIV/HCV co-infection differences similarities between HIV HCV disease paradigms, thereby allowing extrapolation lessons learned care patients with or co-infections Strategies for managing HCV-co-infected using...
A number of open-label studies have suggested the potential benefit rituximab (RTX) in systemic lupus erythematosus (SLE). However, 2 recent randomized controlled trials (RCTs) RTX, primary end points were not met. We undertook this study to evaluate safety and efficacy RTX off-trial patients with SLE seen regular clinical practice.We analyzed prospective data from French AutoImmunity Rituximab (AIR) registry, which includes on autoimmune disorders treated RTX.One hundred thirty-six received...
AimsThe aim of this study was to determine whether clopidogrel plus aspirin provides greater protection against major cardiovascular events than alone in patients with peripheral arterial disease (PAD).
The multicenter national Mortalité 2005 survey aimed at describing the distribution of causes death among HIV-infected adults in France and its changes as compared with 2000.Physicians involved management HIV infection notified deaths documented using a standardized questionnaire similar to previous performed 2000.Overall, 1042 were (vs 964 2000): median age, 46 years 41 years); men, 76%; last CD4 cell count, 161/mm 94). proportion underlying due AIDS decreased (36% vs 47% 2000), cancer not...
Objective Regulatory T cells (Tregs) prevent autoimmunity and control inflammation. Consequently, any autoimmune or inflammatory disease reveals a Treg insufficiency. As low-dose interleukin-2 (ld-IL2) expands activates Tregs, it has broad therapeutic potential. Aim We aimed to assess this potential select diseases for further clinical development by cross-investigating the effects of ld-IL2 in single trial treating patients with 1 11 diseases. Methods performed prospective, open-label,...
From 1979 to 2004, 22 patients were seen with leiomyosarcomas of the inferior vena cava (IVC). Twenty treated surgically. Involvement IVC included infrarenal segment in 3 cases, suprarenal and/or retrohepatic 13, and suprahepatic 4. Nineteen underwent wide tumor resection followed by ligation 5 replacement a PTFE prosthesis cavoplasty 1. An intracardiac extension was resected during hypothermic circulatory arrest 1 patient. Vascular exclusion liver used cases simple clamping 13 cases. There...
The risk of severe infection is a crucial factor in the assessment short-term risk:benefit ratio biologic drugs rheumatoid arthritis (RA). There no increase infections RA patients treated with rituximab (RTX) controlled trials, but this has not yet been assessed daily practice. We undertook study to investigate occurrence and factors for off-trial using data from AutoImmunity Rituximab (AIR) registry.The AIR registry was set up by French Society Rheumatology. charts were reviewed.Of enrolled...