Vincent Di Martino
A5039684397- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Diseases and Immunity
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis Viruses Studies and Epidemiology
- Adrenal Hormones and Disorders
- Systemic Lupus Erythematosus Research
- Hormonal Regulation and Hypertension
- Alcohol Consumption and Health Effects
- Abdominal vascular conditions and treatments
- HIV/AIDS drug development and treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Parasitic infections in humans and animals
- Pancreatitis Pathology and Treatment
- Chronic Lymphocytic Leukemia Research
- Spondyloarthritis Studies and Treatments
- Parasitic Infections and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Amoebic Infections and Treatments
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
Hospital Virgen de la Salud
2020-2025
Hospital Provincial de Conxo
2020-2025
Hôpital Privé Jean Mermo
2015-2025
Centre Hospitalier Universitaire de Besançon
2016-2025
Université de franche-comté
2014-2025
Inserm
2001-2025
Azienda di Rilievo Nazionale ed Alta Specializzazione
2024-2025
Economic & Social Sciences, Health Systems & Medical Informatics
2023
Institut de Recherche pour le Développement
2023
University of Palermo
2020-2021
The natural history of hepatitis C virus (HCV) infection in human immunodeficiency (HIV)-infected patients has never been studied according to the concept liver fibrosis progression. aim this work was assess progression rate HIV-HCV coinfected and infected by HCV only. A cohort 122 compared with a control group HIV-negative HCV-infected patients. Groups were matched age, sex, daily alcohol consumption, age at infection, duration route infection. defined as ratio between stage (METAVIR...
Despite the rising incidence of obesity and diabetes, there is little emphasis on morbidity mortality from obesity-related cirrhosis, usually considered a rare asymptomatic condition. Our aim was to assess survival occurrence hepatocellular carcinoma complications hepatic insufficiency in cryptogenic cirrhosis compared with other origins. We analyzed retrospectively 27 overweight patients (CC-O), 10 lean (CC-L) 391 hepatitis C virus-related (C-HCV). In CC-O patients, detected later life than...
Hepatitis C virus (HCV)–related liver fibrosis progression is accelerated in human immunodeficiency (HIV)–infected patients. The effect of protease inhibitor (PI) therapy on unknown. aim this work was to analyze the impact PI HCV–related HIV/HCV coinfected We evaluated a long–term follow–up retrospective cohort study influence antiretroviral containing 182 consecutive At biopsy, 63 patients had received and 119 never been treated with PI. Relationships between histologic features, age,...
Hepatitis B virus (HBV) resistance to lamivudine has not been extensively documented in human immunodeficiency (HIV)-infected patients. We studied the long-term incidence of HBV HIV-positive Sixty-six HIV-HBV-coinfected patients were while receiving (150 mg twice daily) as a part antiretroviral therapy. All these had detectable serum DNA at beginning Serum was quantified by molecular hybridization. Sequence analysis polymerase performed who became resistant lamivudine. After 2 months...
In this study we analyzed the influence of human immunodeficiency virus (HIV) infection on course chronic hepatitis C through multivariate analysis including age, alcohol consumption, immune status, and (HCV)-related virologic factors. Eighty HIV-positive 80 HIV-negative injection drug users included between 1980 1995 were matched according to gender, duration HCV followed-up during 52 months. The progression cirrhosis was primary outcome measure. impact HIV HCV-RNA load, histologic activity...
Female sex is a protective factor for the progression of fibrosis in patients with chronic hepatitis C virus (HCV) infection. Experimental data suggest that estrogens may have an antifibrotic effect. The objective this study was to evaluate influence past pregnancies, oral contraceptives, menopause, and hormone replacement therapy (HRT) on liver HCV-infected women. Four hundred seventy-two women received survey regarding prior use contraceptives HRT. impact these variables its were evaluated...
There is debate over the effects of long-term oral fluoroquinolone therapy in patients with advanced cirrhosis. We performed a randomized controlled trial to evaluate treatment norfloxacin on survival double-blind 291 Child-Pugh class C cirrhosis who had not received recent therapy. The study was at 18 clinical sites France from April 2010 through November 2014. Patients were randomly assigned groups given 400 mg (n = 144) or placebo 147) once daily for 6 months. evaluated monthly first...
Background. An increased incidence of alveolar echinococcosis (AE) in patients with immunosuppression (IS) has been observed; our aim was to study this association and its characteristics. Methods. Fifty AE cases IS-associated conditions (ISCs) before or at diagnosis were collected from the French registry (1982–2012, 509 cases). There 30 cancers, 9 malignant hematological disorders, 14 chronic inflammatory diseases, 5 transplants, 1 case AIDS; had ≥2 ISCs. Characteristics 42 IS/AE 187...
Various critical events, liver related or not, occur in patients with compensated cirrhosis, but their respective burden remains to be prospectively assessed. The aim of this prospective cohort study involving 35 French centers was capture the whole spectrum complications occurring viral cirrhosis (VC) using competing risks analyses. Inclusion criteria were: histologically proven resulting from hepatitis C virus (HCV) B (HBV); Child‐Pugh A; and no previous hepatic complications. considered...
The best predictors of short- and medium-term mortality cirrhotic patients receiving intensive care support are unknown.We conducted meta-analyses from 13 studies (2523 cirrhotics) after selection original articles response to a standardized questionnaire by the corresponding authors. End-points were in-ICU, in-hospital, 6-month in ICU survivors. A total 301 pooled analyses, including 95 analyses restricted among survivors, considering 249 variables (including reason for admission, organ...
The aim of this work was to develop an individualized score for predicting hepatocellular carcinoma (HCC) in patients with hepatitis C (HCV)‐compensated cirrhosis. Among 1,323 HCV cirrhosis enrolled the French prospective ANRS CO12 CirVir cohort, 720 and 360 were randomly assigned training validation sets, respectively. Cox's multivariate model used predict HCC, after which a nomogram computed assess risk. During follow‐up (median, 51.0 months), 103 39 developed HCC Five variables...