A5066341447- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Liver Diseases and Immunity
- Microscopic Colitis
- Diet, Metabolism, and Disease
- Gastrointestinal motility and disorders
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Sexual function and dysfunction studies
- Hepatitis C virus research
- Alcohol Consumption and Health Effects
- Helicobacter pylori-related gastroenterology studies
- Urinary Bladder and Prostate Research
- Diet and metabolism studies
- Pancreatitis Pathology and Treatment
- Immunotherapy and Immune Responses
- Pharmacology and Obesity Treatment
- Pelvic floor disorders treatments
- Hormonal and reproductive studies
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Inflammatory Biomarkers in Disease Prognosis
- Gastroesophageal reflux and treatments
- Obstructive Sleep Apnea Research
- Regulation of Appetite and Obesity
Ehime University
2016-2025
Ehime University Hospital
2015-2024
ProQuest (United States)
2024
National Institute of Technology, Niihama College
2024
Saiseikai Ibaraki Hospital
2024
Health Services Center
2021-2024
National Institute of Diabetes and Digestive and Kidney Diseases
2024
Sumitomo Besshi Hospital
2024
Ehime Prefectural Central Hospital
2024
GTx (United States)
2023
Most studies have investigated the association between parental socioeconomic factors and dental caries in children based on educational income levels; focusing occupation, however, been relatively limited. This cross-sectional study examined associations occupations levels of education household prevalence Japanese aged 3 years.Study subjects were 6315 children. Oral examination results obtained from parents or guardians, who transcribed information recorded by medical staff at a public...
Subclinical hypothyroidism (SCH) has been associated with type 2 diabetes mellitus. However, it is unknown whether common complications of diabetes, such as diabetic nephropathy, are also present SCH. Here, we investigated the association between SCH and nephropathy among Japanese patients In this multicenter cross-sectional study, recruited 414 who had no previous history thyroid disease. Serum hormone levels urinary albumin:creatinine ratio were measured. was defined an elevated...
Background The effect of cigarette smoking on the onset nonalcoholic fatty liver disease (NAFLD) is unclear, especially that associated with drinking small amounts alcohol. We conducted a longitudinal study to investigate relationship between and NAFLD onset, which was stratified according amount alcohol consumed. Methods enrolled 7,905 Japanese subjects who had received annual health checkups more than twice April 2003 August 2013, 4,045 whom met at least one following exclusion criteria...
Visceral adipose tissue (VAT) inflammation has been linked to the pathogenesis of insulin resistance and metabolic syndrome. VAT recently established as a new component immune system is involved in production various adipokines cytokines. These molecules contribute inducing accelerating systemic resistance. In this report, we investigated role B cell-activating factor (BAFF) induction We BAFF levels sera obese mice. mice, were preferentially increased compared these normal control Next,...
There are few effective medications for non-alcoholic steatohepatitis (NASH). We investigated the efficacy of ipragliflozin (selective sodium-glucose cotransporter-2 inhibitor [SGLT2I]) treatment patients with type 2 diabetes mellitus (T2DM) complicated by fatty liver disease (NAFLD).We prospectively enrolled T2DM NAFLD treated at our institutions from January 2015 to December 2016. Patients received oral (50 mg/day) once daily 24 weeks. Body composition was evaluated using an InBody720...
Although certain allergic diseases have been reported to be associated with the prevalence of functional dyspepsia (FD) and irritable bowel syndrome (IBS), it is unclear whether presence multiple further increases FD IBS. The aim this study determine issue in young people.
Allergic diseases and ulcerative colitis (UC) share pathophysiological similarities. This study aimed to investigate the unclear association between allergic mucosal healing (MH), an important factor in prognosis of UC. We studied 289 Japanese patients with Information on (bronchial asthma, atopic dermatitis, pollen allergy, food drug allergy), as diagnosed by physicians, was collected through self-reported questionnaires. The definition MH Mayo Endoscopic Score 0. each disease its...
Pheochromocytomas occur in the adrenal medulla and present with various symptoms associated excessive catecholamine production. Although pheochromocytomas ectopic ACTH-producing tumors hyper-interleukin-6emia (hyper-IL-6emia) have been reported, those both diseases simultaneously not reported. In hyper-IL-6emia, disease characteristics relationship between each hormone cytokine are unknown. Herein, we report a case of 56-year-old woman stroke whose computed tomography scans abdomen revealed...
Adult intussusception (AI) is often associated with organic diseases. However, few studies have examined the causes of AI in Japanese patients. This study aimed to elucidate clinical characteristics due malignancy From 2013 2021, 54 patients (≥ 20 years) diagnosed at our hospital were enrolled and divided into two groups according cause (malignancy group, n = 26; other diseases 28). The patients' retrospectively evaluated. Patients group significantly older than those (p < 0.001). cutoff...
ABSTRACT Fulminant type 1 diabetes is a rare but severe condition that can develop rapidly, often in association with viral infections. In this case, coxsackievirus B6 antibody levels were elevated after disease onset, though its significance remains unclear. This highlights the importance of thorough screening fulminant and need for further research to better understand potential contributing factors, including post‐vaccination contexts.
Aims: Transmission of hepatitis E virus (HEV) from wild boar to humans has been reported, particularly Japan. We attempted clarify this issue. Methods: assessed the IgG class antibodies against HEV (anti‐HEV) in serum samples taken 406 living Ehime area western Japan 2001 2004, which 392 were captured (wild‐caught boar) and 14 had kept a breeding farm (bred boar). Results: Anti‐HEV positive rate bred (10/14, 71.4%) was significantly higher than wild‐caught (100/392, 25.5%) ( P < 0.001)....
Patients with hepatitis C virus (HCV) frequently show glucose intolerance. Diabetes mellitus (DM) has been proposed to be a risk factor for hepatocellular carcinoma (HCC).The aim of this study is clarify the influence intolerance as evaluated by 75 g oral tolerance test (OGTT) on hepatocarcinogenesis in patients HCV.This was carried out cohort 197 HCV who had not previously diagnosed having DM. All underwent OGTT at entry. They were also screened HCC and, thereafter, rate compared between...
Objective We estimated the prevalence of nocturnal intermittent hypoxia, a surrogate marker obstructive sleep apnoea, among type 2 diabetes mellitus (T2DM) patients and examined association between hypoxia microvascular diseases. Design methods recruited 513 Japanese (292 men 221 women) with T2DM. Nocturnal was diagnosed using 3% oxygen desaturation index, less than five events per hour corresponding to normal or more hypoxia. Results The 45.4% T2DM patients. group older had higher BMI,...
Weight reduction is important in patients with sleep-disordered breathing (SDB). In Japanese patients, slight weight effective for improving the severity of SDB. However, effect after administration sodium glucose co-transporter 2 (SGLT2) inhibitor SDB remains unclear. The aim this study was to evaluate improvement from baseline dapagliflozin (5 mg) once daily 24 weeks among obesity and type diabetes mellitus. Thirty mellitus were enrolled a 24-week, prospective, open-label, single-arm,...
Poor lifestyle habits may worsen nonalcoholic fatty liver disease (NAFLD), with progression to steatohepatitis (NASH) and cirrhosis. This study investigated the association between glycemic control status hepatic histological findings elucidate effect of on NAFLD. observational included 331 patients diagnosed NAFLD by biopsy. Effects were evaluated comparing following four groups defined glycosylated hemoglobin (HbA1c) level at time diagnosis: ≤5.4%, 5.5%-6.4%, 6.5%-7.4%, ≥7.5%. Compared...