Ken Shimizu

ORCID: 0000-0002-8761-7534
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About
Contact & Profiles
Research Areas
  • Childhood Cancer Survivors' Quality of Life
  • Cancer survivorship and care
  • Palliative Care and End-of-Life Issues
  • Family Support in Illness
  • Cancer and Skin Lesions
  • Breast Cancer Treatment Studies
  • Intensive Care Unit Cognitive Disorders
  • Cancer-related gene regulation
  • Cerebrovascular and genetic disorders
  • Biomarkers in Disease Mechanisms
  • Breast Lesions and Carcinomas
  • Medical Imaging and Pathology Studies
  • Veterinary medicine and infectious diseases
  • Urinary and Genital Oncology Studies
  • Cancer-related cognitive impairment studies
  • Lymphoma Diagnosis and Treatment
  • Metastasis and carcinoma case studies
  • Bladder and Urothelial Cancer Treatments
  • Breast Implant and Reconstruction
  • Anesthesia and Sedative Agents
  • Ovarian cancer diagnosis and treatment
  • Music Therapy and Health
  • Toxin Mechanisms and Immunotoxins
  • Acute Lymphoblastic Leukemia research
  • Cervical Cancer and HPV Research

Social Insurance Saitama Chuo Hospital
2013-2023

Japanese Foundation For Cancer Research
2021-2023

Saitama Medical University
2015-2023

Waseda University
2023

Consumers Union
2023

The Cancer Institute Hospital
2020-2022

Tokyo Metropolitan Children's Medical Center
2022

Cancer Institute (WIA)
2021

Tottori University
2020-2021

National Cancer Center
2011-2020

Background: As a parameter for the evaluation of vestibular evoked myogenic potential (VEMP), amplitude has been used clinically.However, significance latency not considered.Objective: To clarify diagnostic value latencies VEMP. Design:We reviewed records VEMP patients with various diseases and compared them healthy volunteers.Setting: Data were collected from in an outpatient clinic tertiary care center volunteers.Subjects: Clinical 134 (61 men 73 women, aged 20-75 years) reviewed.Diagnoses...

10.1001/archotol.127.9.1069 article EN Archives of Otolaryngology - Head and Neck Surgery 2001-09-01

ErbB2-negative breast tumors represent a significant therapeutic hurdle because of lack effective molecular targets. Although NOTCH proteins are known to be involved in mammary tumorigenesis, the functional significance these is not clear. In present study, we examined expression activated receptors human cancer cell lines, including and ErbB2-positive lines. Activated NOTCH1 NOTCH3 generated by gamma-secretase were detected most lines tested, both CSL-mediated transcription. Down-regulation...

10.1158/0008-5472.can-07-1597 article EN Cancer Research 2008-03-13

Background Several studies have reported that physical loading related to competitive sports activities is associated with lumbar intervertebral disk degeneration. However, the association between types of and degeneration has not been clarified. Hypothesis The frequencies may vary sport because different postures actions specific each sport. Study Design Cross-sectional study (prevalence); Level evidence, 3. Methods participants were 308 well-trained university athletes (baseball players,...

10.1177/0363546508323252 article EN The American Journal of Sports Medicine 2008-09-17

Intraosseous benign notochordal cell tumors are recently recognized conditions that may undergo malignant transformation to classic chordomas. This study attempts define the morphologic and immunohistochemical characteristics of 34 by contrasting them with chordomas vestiges in fetal intervertebral discs. Benign were characterized well-demarcated though unencapsulated sheets adipocyte-like vacuolated less eosinophilic cells within axial bones. The round nuclei mildly polymorphic but bland....

10.1097/01.pas.0000126058.18669.5d article EN The American Journal of Surgical Pathology 2004-05-17

Recent investigations have demonstrated the utility of monoclonal antibody D2-40 as a marker for lymphatic endothelium. can be used on formalin-fixed and paraffin-embedded materials. Our objective was to elucidate, using immunohistochemistry, differences among capillary hemangiomas, especially between kaposiform hemangioendothelioma (KHE) tufted angioma (TA). We studied four cases KHE, nine TA, 31 other vascular tumors. Antibodies against CD31, CD34, factor VIII-related antigen, GLUT1 were...

10.1111/j.1600-0560.2006.00461.x article EN Journal of Cutaneous Pathology 2006-05-30

Most studies have investigated the association between parental socioeconomic factors and dental caries in children based on educational income levels; focusing occupation, however, been relatively limited. This cross-sectional study examined associations occupations levels of education household prevalence Japanese aged 3 years.Study subjects were 6315 children. Oral examination results obtained from parents or guardians, who transcribed information recorded by medical staff at a public...

10.1186/s12199-017-0688-6 article EN cc-by Environmental Health and Preventive Medicine 2017-12-01

The majority of orthopaedic problems experienced by competitive swimmers are related to pain in the shoulder, low back, and knee. Three 39 national swim team members were hampered their performance due lumbar disk herniation at an international competition 2001. There has been no previous research into degeneration elite swimmers.Excessive swimming activities accelerate degeneration.Case control study; Level evidence, 3.Fifty-six (high-load group, 35 men 21 women; mean age, 19.6 years) a...

10.1177/0363546507300259 article EN The American Journal of Sports Medicine 2007-04-04

Although the implementation of routine screening for distress is desirable, doing so difficult in today's busy clinical oncology practice. We developed 'Distress Screening Program Ambulatory Care' (DISPAC program) as a practical means and facilitating treatment major depression adjustment disorders cancer patients. This study assessed feasibility usefulness DISPAC program actual situations.As part program, nurses administered psychological measure, Distress Impact Thermometer (DIT), to...

10.1002/pon.1616 article EN Psycho-Oncology 2009-08-11

Background Axillary reverse mapping (ARM) is a novel technique for preserving the upper extremity lymphatic pathways during axillary lymph node surgery. However, there no evidence of usefulness ARM patients undergoing sentinel biopsy (SNB). Methods Between August 2009 and July 2012, 372 who underwent SNB procedure breast cancer were enrolled in this study. Using indocyanine green fluorescence indigocarmine blue dye method, we studied relationship between flow (SN). Our aim study was...

10.1002/jso.23528 article EN cc-by-nc Journal of Surgical Oncology 2013-12-06

Major depression and adjustment disorders are common psychiatric in patients with cancer, but they often overlooked clinical oncology settings. The nurse-assisted screening referral program (NASPRP) has been introduced practice to facilitate treatment for major disorders. This study assessed the usefulness of NASPRP compared it usual practice.The consists two stages. In first stage, consecutive newly admitted Oncology/Hematology Unit administered Distress Impact Thermometer (DIT) by nurses...

10.1002/cncr.20992 article EN Cancer 2005-03-15

Abstract Little attention has been paid to sleep disturbance experienced by advanced cancer patients. The purpose of the present study was investigate longitudinal change in and identify factors that associated with predicted among 209 consecutive terminally ill Patients were assessed twice for one item structured clinical interview assessing depression, once at time their registration a palliative care unit (PCU) (baseline) again PCU admission (follow‐up), possible medical psychosocial...

10.1002/pon.1122 article EN Psycho-Oncology 2006-11-06

Abstract Objective : Major depression is a well‐documented risk factor for suicide, and several gender differences in factors suicide exist cancer patients as well the general population. However, no data available regarding among with major depression. Methods We investigated background between suffering from or without suicidal ideation according to by analyzing consultation obtained referred Psychiatry Division. Results Among 5431 patients, 329 males 399 females were diagnosed having...

10.1002/pon.1587 article EN Psycho-Oncology 2009-05-26

It is known that depression and anxiety occur more frequently in pancreatic cancer patients than those with other malignancies. However, few studies have assessed using reliable psychiatric diagnostic tools. The purpose of this study was to determine the prevalence among before 1 month after start anticancer treatment tools, identify factors predict their occurrence.Pancreatic were consecutively recruited. Structured clinical interviews used presence affective disorders, disorders adjustment...

10.1093/jjco/hyv169 article EN Japanese Journal of Clinical Oncology 2015-11-19

Although various factors thought to be correlated with anxiety in cancer patients, relative importance of each were unknown. We tested our hypothesis that personality traits and coping styles explain lung patients a greater extent than other factors. A total 1334 consecutively recruited selected, data on cancer-related variables, demographic characteristics, health behaviors, physical symptoms psychological consisting obtained. The participants divided into groups or without significant...

10.1093/jjco/hyv024 article EN Japanese Journal of Clinical Oncology 2015-03-10

Abstract The objective of this study was to describe the applicability and dropout pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer. Psychiatrists treated cancer on basis algorithm. For discussing problems related algorithm, we reviewed reasons non‐application within a week initiation treatment. applied 54 59 cases (applicability rate, 92%). were as follows: need add benzodiazepine an antidepressant 4 choose alprazolam despite depression...

10.1002/pon.1213 article EN Psycho-Oncology 2007-04-27

To examine whether habitual dietary intake of marine-origin n-3 polyunsaturated fatty acids (MOPUFA), eicosapentaenoic acid (EPA) and docosahexaenoic (DHA), are associated with functional mobility in the community-dwelling oldest old, 85 years or older, who at high risk for physical disability. A cross-sectional study. community-based survey conducted university research center home-based. Four hundred seventeen (189 men, 228 women) out 542 participants baseline examination Tokyo Oldest Old...

10.1007/s12603-012-0389-1 article EN cc-by-nc-nd The journal of nutrition health & aging 2012-09-30

Abstract Objective : Major depressive disorder (MDD) and adjustment (AD) are common psychiatric disorders in cancer patients but often overlooked clinical oncology settings. We introduced a screening program utilizing the Distress Impact Thermometer (DIT) to identify MDD AD outpatients receiving chemotherapy. This study assessed usefulness of program. Methods Pharmacists administered DIT consecutive undergoing chemotherapy at an outpatient clinic. Psychiatric treatment was recommended all...

10.1002/pon.1945 article EN Psycho-Oncology 2011-03-07
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