A5088839805- Breast Cancer Treatment Studies
- Advanced Radiotherapy Techniques
- Hematopoietic Stem Cell Transplantation
- Immunodeficiency and Autoimmune Disorders
- Management of metastatic bone disease
- Global Cancer Incidence and Screening
- AI in cancer detection
- Acute Myeloid Leukemia Research
- Oral and Maxillofacial Pathology
- Effects of Radiation Exposure
- Sarcoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Radiation Therapy and Dosimetry
- Bone Tumor Diagnosis and Treatments
- CAR-T cell therapy research
- Breast Implant and Reconstruction
National Cancer Centre Singapore
2020-2024
SingHealth
2024
Duke-NUS Medical School
2020-2021
PURPOSE Neoadjuvant chemotherapy (NAC) is increasingly used in breast cancer. Predictive modeling useful predicting pathologic complete response (pCR) to NAC. We test machine learning (ML) models predict pCR cancer and explore methods of handling missing data. METHODS Four hundred ninety-nine patients with treated NAC two centers Singapore (National Cancer Centre [NCCS] KK Hospital) between January 2014 December 2017 were included. Eleven clinical features train five different ML models....
Chordomas are rare and locally aggressive tumours that arise from embryonic remnants of the notochord, with a predilection for skull base, mobile spine, sacrum. Sacral or sacrococcygeal chordomas can be particularly difficult to manage because their large size at presentation involvement adjacent organs neural structures. Although recommended definitive therapy such is either en bloc resection without adjuvant radiotherapy (RT) fractionated RT charged particle therapy, older and/or less-fit...