- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Aquaculture disease management and microbiota
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Immune Response and Inflammation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Vibrio bacteria research studies
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac and Coronary Surgery Techniques
- Catalytic C–H Functionalization Methods
- Bioactive Compounds and Antitumor Agents
- Biomedical Ethics and Regulation
- Synthesis of Indole Derivatives
- Atherosclerosis and Cardiovascular Diseases
- Axial and Atropisomeric Chirality Synthesis
- Sulfur-Based Synthesis Techniques
- Lung Cancer Treatments and Mutations
- PI3K/AKT/mTOR signaling in cancer
- Tissue Engineering and Regenerative Medicine
- Shoulder Injury and Treatment
- Social Capital and Networks
Guangdong Pharmaceutical University
2023-2024
Guangdong Ocean University
2020-2023
Third Affiliated Hospital of Sun Yat-sen University
2018-2022
Sun Yat-sen University
2015-2022
Qingdao National Laboratory for Marine Science and Technology
2020
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2020
The First Affiliated Hospital, Sun Yat-sen University
2015-2016
Guangdong General Hospital
2013
Northeast Normal University
2006
Changchun University
2003
An unprecedented electrochemically regioselective C–H phosphorothiolation and S- to C-[1,4] phosphonyl migration involving indolizines, elemental sulfur, H-phosphonates in an undivided cell has been developed.
Abstract A DBU‐promoted [3+2] cyclization/retro‐Mannich cascade reaction of N ‐aminoisoquinolinium and ‐aminoquinolinium derivatives with para ‐quinone methides has been established, employing a C=C double bond cleavage. broad range salts, are well tolerated, providing the corresponding rearrangement products. Moreover, scaled‐up reactions diverse derivatizations products were also investigated discussed.
Non-small cell lung cancer (NSCLC) is a major type of human and the primary cause cancer-associated cases mortality worldwide. Phosphatase tensin homolog (PTEN) potent tumor suppressor gene in various types. The aim current study was to explore role PTEN its associated regulatory mechanisms NSCLC. Firstly, expression detected using western blotting variety NSCLC lines. results revealed that compared with normal control cells, levels were significantly decreased lines (P<0.01). Short hairpin...
3D ordered macroporous multicomponent composite materials have been fabricated by electrochemical deposition of aniline on the inner surface carbon; maximum thickness polyaniline (PANI) deposited is dependent concentration as well dimension windows in carbon.
This study applied a complex bioinformatics analysis to explore the hub regulators and immune network further elucidate molecular mechanisms of lung adenocarcinoma (LUAD) regulation.LUAD immunological microenvironment features microenvironment-related differential expression genes (DEGs) were identified by ESTIMATE algorithm linear models for microarray analyses (LIMMA), respectively. CIBERSORT Igraph algorithms construct LUAD-related immunocyte infiltration regulatory network. Kaplan-Meier...
We apply the bioinformatics method to excavate potential genes and therapeutic targets associated with valvular atrial fibrillation (VAF).The downloaded gene expression files from omnibus (GEO) included patients primary severe mitral regurgitation complicated sinus or rhythm. Subsequently, differential in left right atrium was analyzed by R software. Additionally, weighted correlation network analysis (WGCNA), principal component (PCA), linear model for microarray data (LIMMA) algorithm were...
Comprehensive Summary Two reaction modes for metal‐free [3 + 2] cyclization of N ‐aminopyridinium derivatives with β ‐alkoxyvinyl trifluoromethylketones have been described through selective C—O or C—O/C—C bond cleavage. This strategy can also be extended to the enaminones and bromoalkynes. A broad range ‐aminopyridinium, ‐aminoquinolinium, ‐aminoisoquinolinium salts are well tolerated, enabling divergent synthesis trifluoroacylated, non‐substituted, acylated, brominated pyrazolo[1,5‐ a...
Objective To retrospectively analyze the surgical methods and efficacy in 70 cases of type A aortic dissection patients over 65 years old.Methods From January 2005 to May 2012,70 old received treatment.Among them,there were 47 males aged 78 with mean 71,23 females,aged 72 68.55 acute onset,while 15 chronically onset.Different selected depend on patients' situations.We followed up all after discharged from hospital continue observe their health situation evaluate therapeutic effects.Results...
Vibrio alginolyticus is responsible for significant economic losses in the fish industry. It urgent to develop a vaccine against V. alginolyticus. In this study, recombinant Lactococcus lactis expressing VscO protein of (Lc-pMG36e-vscO) constructed. The Lc-pMG36e-vscO has good hereditary stability. immune responses pearl gentian grouper (Epinephelus fuscoguttatus (♀) × E. lanceolatu (♂)) vaccinated with are evaluated. titers specific antibody immunized displayed an upward and then downward...