A5102913157- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Hypothalamic control of reproductive hormones
- Neuroendocrine regulation and behavior
- Hormonal Regulation and Hypertension
- Protein Hydrolysis and Bioactive Peptides
- Neuroscience and Neuropharmacology Research
- Peptidase Inhibition and Analysis
- Pain Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Apelin-related biomedical research
- S100 Proteins and Annexins
- Neurological Disease Mechanisms and Treatments
- Signaling Pathways in Disease
- Anesthesia and Neurotoxicity Research
- Regulation of Appetite and Obesity
- Growth Hormone and Insulin-like Growth Factors
- Neurobiology and Insect Physiology Research
- Vitamin K Research Studies
- Neonatal and fetal brain pathology
- Biochemical effects in animals
- Stress Responses and Cortisol
- Cancer, Stress, Anesthesia, and Immune Response
- Retinal Diseases and Treatments
University of Pecs
2015-2024
Conference Board
2020
University of Debrecen
2010-2018
Országos Pszichiátriai és Neurológiai Intézet
2018
Hungarian Academy of Sciences
2002-2007
It has been observed that pituitary-adenylate cyclase activating polypeptide (PACAP) rescued DAergic neurons from neurodegeneration and improved motor alterations induced by 6-hydroxy-dopamine (6-OHDA) in rat parkinsonian models. Recently we investigated the molecular background of neuroprotective effect PACAP DA-based using rotenone-induced snail 6-OHDA-induced models Parkinson's disease. The behavioural activity, monoamine (DA serotonin), metabolic enzyme (S-COMT, MB-COMT MAO-B) PARK7/DJ-1...
Background The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) plays pivotal roles in immunity and inflammation. So far, potential immune-modulatory properties of PACAP have not been investigated experimental ileitis. Methodology/Principal Findings Mice were perorally infected with Toxoplasma (T.) gondii to induce acute ileitis (day 0) treated daily synthetic PACAP38 from day 1 6 post infection (p.i.; prophylaxis) or 4 p.i. (therapy). Whereas placebo-treated control...
Pituitary adenylate cyclase activating polypeptide (PACAP) is an important neurotrophic factor influencing differentiation of neuronal elements and exerting protecting role during traumatic injuries or inflammatory processes the central nervous system. Although increasing evidence available on its presence function in various peripheral tissues, little known about PACAP formation skeletal components. To this end, we aimed to map signalling developing cartilage under physiological conditions...