A5087272006- Neuroscience and Neural Engineering
- 3D Printing in Biomedical Research
- Molecular Communication and Nanonetworks
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- interferon and immune responses
- Cell Image Analysis Techniques
- Pluripotent Stem Cells Research
- Plasmonic and Surface Plasmon Research
- Biosensors and Analytical Detection
- Gold and Silver Nanoparticles Synthesis and Applications
- IoT and Edge/Fog Computing
- Microfluidic and Bio-sensing Technologies
- Advanced Memory and Neural Computing
- Neural dynamics and brain function
- bioluminescence and chemiluminescence research
- Nanopore and Nanochannel Transport Studies
- Biomedical and Engineering Education
- Planarian Biology and Electrostimulation
- Smart Agriculture and AI
- Photonic and Optical Devices
- Microfluidic and Capillary Electrophoresis Applications
University of California, Santa Cruz
2021-2024
Bethel University
2016-2019
Abstract Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology physiology of their vivo counterparts. Here, we have developed a multiplex platform automates individual organoids isolated microenvironments at user-defined media flow rates. Programmable workflows allow use multiple reagent reservoirs may be applied direct differentiation, study temporal variables, grow cultures long term....
The Internet of Things (IoT) provides a simple framework to control online devices easily. IoT is now commonplace tool used by technology companies but rarely in biology experiments. can benefit cloud research through alarm notifications, automation, and the real-time monitoring We developed an architecture biological implemented it lab Lab for electrophysiology, microscopy, microfluidics were created from ground up be part unified architecture. system allows each device monitored controlled...
Simultaneous longitudinal imaging across multiple conditions and replicates has been crucial for scientific studies aiming to understand biological processes disease. Yet, systems capable of accomplishing these tasks are economically unattainable most academic teaching laboratories around the world. Here, we propose Picroscope, which is first low-cost system simultaneous made primarily using off-the-shelf 3D-printed materials. The Picroscope compatible with standard 24-well cell culture...
Abstract The analysis of tissue cultures, particularly brain organoids, requires a sophisticated integration and coordination multiple technologies for monitoring measuring. We have developed an automated research platform enabling independent devices to achieve collaborative objectives feedback-driven cell culture studies. Our approach enables continuous, communicative, non-invasive interactions within Internet Things (IoT) architecture among various sensing actuation devices, achieving...
Plasmon-enhanced optical transmission through arrays of nano-structured holes has led to the development a new generation sensors. In this paper, dramatically simplify standard setups these sensors, we position nanoholes, an LED illumination source and spacer layer directly on top CMOS imager chip. Transmitted light diffracts from nanohole array, spreading into spectrum over space millimeter land as full spectrum. Our chip is used sensor in both liquid gas environment. The monitored...
ABSTRACT Electrophysiology offers a high-resolution method for real-time measurement of neural activity. The vast amount data generated requires efficient storage and sophisticated processing to extract function network dynamics. However, analysis is often challenging due the need multiple software tools with different runtime dependencies. Longitudinal recordings from high-density microelectrode arrays (HD-MEAs) can be considerable size local storage, complicating management, sharing,...
The SARS-CoV-2 pandemic has challenged humankind's ability to quickly determine the cascade of health effects caused by a novel infection. Even with unprecedented speed at which vaccines were developed and introduced into society, identifying therapeutic interventions drug targets for patients infected virus remains important as new strains evolve, or future coronaviruses may emerge that are resistant current vaccines. application transcriptomic RNA sequencing samples shed light on pathways...
Abstract The Internet of Things (IoT) provides a simple framework to easily control online devices. IoT is now commonplace tool used by technology companies, but it rarely in biology experiments. can benefit research through alarm notifications, automation, and the real-time monitoring We developed implemented an architecture biological devices our own electrophysiology, microscopy, microfluidic so that may be controlled unified architecture. system allows each device monitored web tool....
New cell culture techniques have led to complex tissue models in biological experiments. For example, 3-D cerebral organoids provide a more realistic model of the human cortical tissue. However, these experiments are restricted by high costs and limited labor. A massively scalable cost efficient platform for would benefit genomics, neuroscience, translational medicine enabling advanced throughput screens. Cloud computing Internet Things (IoT) new tools managing multiple parallel that...
ABSTRACT Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology physiology of their vivo counterparts. Here, we have developed a multiplex platform automates individual organoids isolated microenvironments at user-defined media flow rates. Programmable workflows allow use multiple reagent reservoirs may be applied direct differentiation, study temporal variables, grow cultures long term....
ABSTRACT Simultaneous longitudinal imaging across multiple conditions and replicates has been crucial for scientific studies aiming to understand biological processes disease. Yet, systems capable of accomplishing these tasks are economically unattainable most academic teaching laboratories around the world. Here we propose Picroscope, which is first low cost system simultaneous made primarily using off-the-shelf 3D-printed materials. The Picroscope compatible with standard 24-well cell...
Abstract The SARS-CoV-2 pandemic has challenged humankind’s ability to quickly determine the cascade of health effects caused by a novel infection. Even with unprecedented speed at which vaccines were developed and introduced into society, identifying therapeutic interventions drug targets for patients infected virus remains important as new strains may evolve, or future coronaviruses emerge, that are resistant current vaccines. application transcriptomic RNA sequencing samples shed light on...
Abstract The SARS-CoV-2 pandemic has challenged humankind’s ability to quickly determine the cascade of health effects caused by a novel infection. Even with unprecedented speed at which vaccines were developed and introduced into society, identifying therapeutic interventions drug targets for patients infected virus remains important as new strains may evolve, or future coronaviruses emerge, that are resistant current vaccines. application transcriptomic RNA sequencing samples shed light on...