A5100712740- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Olfactory and Sensory Function Studies
- Protein Hydrolysis and Bioactive Peptides
- Biochemical effects in animals
- Analytical Chemistry and Chromatography
- Meat and Animal Product Quality
- Natural product bioactivities and synthesis
- Metabolomics and Mass Spectrometry Studies
- Food Chemistry and Fat Analysis
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- Traditional and Medicinal Uses of Annonaceae
- Food Quality and Safety Studies
- Plant biochemistry and biosynthesis
- Plant-derived Lignans Synthesis and Bioactivity
- Phytochemistry and Biological Activities
- Insect Utilization and Effects
- Enzyme Production and Characterization
- Web Data Mining and Analysis
- Medicinal Plant Pharmacodynamics Research
- Nutrition, Health and Food Behavior
- Image Retrieval and Classification Techniques
- Sphingolipid Metabolism and Signaling
- Gut microbiota and health
Beijing Technology and Business University
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Nanjing University
2024
Nanjing Drum Tower Hospital
2024
University of Alberta
2021-2024
The Seventh Affiliated Hospital of Sun Yat-sen University
2021
Sun Yat-sen University
2021
Honghe University
2013
Yunnan Academy of Agricultural Sciences
2011
Tea Research Institute
2011
Hypertension has emerged as a major factor detrimental to human health. Umami peptide IIVFGRQLL from yeast certain ACE inhibitory activity (IC50: 59.35 μM) at 0.14 mg/mL. Moreover, could regulate the systolic blood pressure of spontaneously hypertensive rats model indicating its potential antihypertensive effect. The changes in and sequence during digestion were investigated based on inhibition assays, simulated gastrointestinal digestion, LC-MS/MS. decreased by 39.0% after digestion. It was...
Cancer-targeted drug delivery systems based on nanoparticles (NPs) have been considered promising therapies. In this study, we developed a pH-responsive smart NPs system using silk fibroin (SF), selenium (Se NPs), fingolimod (FTY720), and heptapeptide (T7). The prepared FTY720@T7-SF-Se were spheres with an average diameter of 120 nm, which would contribute to the enhanced permeability retention effects in tumour regions. encapsulation efficiency (EE) was 71.95 ± 3.81%. release FTY720 from...
In cross-modal retrieval, comprehensive image understanding is vital while the scene text in images can provide fine-grained information to understand visual semantics. Current methods fail make full use of text. They suffer from semantic ambiguity independent and overlook heterogeneous concepts image-caption pairs. this paper, we propose a prompt-guided entity inferring distilling (HOPID) network explore nature connection captions learn property-centric representation. Specifically, align...
Bioactive peptides from foods have garnered considerable attention as viable supplements for hypertensive patients. Herein, the antihypertensive effect and mechanism of umami yeast extract were investigated based on pharmacophore model, simulated digestion, spontaneously rat (SHR) molecular docking. Notably, peptide LLLLPKP exhibited favorable angiotensin I-converting enzyme (ACE) inhibitory activity (IC50 = 10.22 μM) in vitro regulated blood pressure SHR model with excellent durability....
Different protein sources can impact gut microbiota composition and abundance, also participate in health regulation. In this study, mice were gavaged with yeast (YP), soybean isolate (SPI), whey (WPI) for 28 days. Body weights showed similar patterns across different administration groups. The ileum YP-supplemented exhibited good morphology, tight-junction (TJ) proteins slightly upregulated. Immunoglobulin (Ig)A, IgM, IgG levels the of groups significantly increased (p < 0.05)....
In order to investigate the effect of ginger on taste components and sensory characteristics in chicken soup, content amino acids, organic 5′-nucleotides, mineral elements were determined soup sample. With added, free acids obviously increased exceeded total amounts soup. The glutamic acid (122.74 μg/mL) was highest among 17 Meanwhile, six detected all increased, which lactic (1523.58 critic (4692.41 1000 μg/mL. 5′-nucleotides had no obvious difference between Compared with a smaller...
To investigate the effect of welsh onion on taste components and sensory characteristics in porcine bone soup, stewing condition was as follows: material-liquid ratio (m/V) 1:1, time 5.0 h, 2.5%. Then, content measured. The free amino acids soup with (PWS) higher than sum (WS) (PS); particularly, umami increased by 35.73% compared PS. Significant increases four organic (lactic acid, pyroglutamic citric acid ascorbic acid), two 5'-nucleotides (5'-AMP 5'-GMP) three mineral elements (K, Ca Mg)...
Sheep tail fat and prickly ash play an important role in improving the umami taste of mutton soup. In this work, effects on key compounds stewed sheep soup were investigated. Results showed that intensity cooked with 0.2% increased significantly. The concentration organic acids free amino significantly addition ash. succinic acid (2.637 to 4.580 mg/g) Thr (2.558 12.466 most among acids, respectively. Spearman’s correlation analysis elucidated seven positively correlated (correlation...
High-sodium intake is associated with the increased risk of hypertension and cardiovascular disease. Monitoring analyzing sodium content in commercial food instructive for reducing general population. The 4082 foods across 12 groups 41 categories was collected analyzed, including 4030 pre-packaged 52 artisanal foods. group highest average (6888.6 mg/100 g) contained sauces, dressings, springs dips, followed by bean products (1326.1 fish, meat egg (1302.1 g). all 1018.6 g. Meanwhile,...
The key aroma compounds in the fruit of Litsea pungens Hemsl. (LPH) were concentrated through solvent-assisted flavor evaporation (SAFE) and characterized by gas chromatography-mass spectrometry-olfactometry (GC-MS/O), quantitative descriptive analysis (QDA), odor activity values (OAVs), addition test. results showed that LPH contained 31 aroma-active (flavor dilution, FD = 9). Among them, 30 odorants quantified standard curve method. OAV 25 had OAVs ≥ 1, which could be considered as potent...
A nontargeted fingerprinting approach combined with the chemometrics method and sensory analysis was used to assess differences in taste-chemical compositions of chicken breast soup different ages their qualities. The evaluation results showed that overall taste as well sourness, saltiness, umami scores were increased age chicken. Fifty-nine compounds identified from four samples by liquid chromatography-tandem quadrupole time-of-flight mass spectrometry (LC-QTOF-MS/MS), total content...
Aphanomyces euteiches causes root rot in pea, leading to significant yield losses. However, the metabolites involved this pathosystem have not been thoroughly studied. This study aimed fill gap and explore mechanisms of bacterial suppression A. via untargeted metabolomics using pea grown a controlled environment. Chemical isotope labeling (CIL), followed by liquid chromatography-mass spectrometry (LC-MS), was used for metabolite separation detection. Univariate multivariate analyses showed...
Abstract From the stems of Schisandra rubriflora , two novel partially saturated dibenzocyclooctene lignans, named rubriflorin A ( 1 ) and B 6 ), as well seven known lignans kadsumarin 2 kadsurin 3 heteroclitin 4 C 5 D 7 interiorin 8 9 were isolated. The structures new compounds established on basis spectral analysis (5 R ,6 S ,7 ,8 ,13a )‐8‐(acetyloxy)‐5,6,7,8‐tetrahydro‐1,2,3,13‐tetramethoxy‐6,7‐dimethylbenz([3,4]cycloocta[1,2‐ f ][1,3]benzodioxol‐5‐yl (2 Z )‐2‐methylbut‐2‐enoate (6 ,12a...