A5102941558- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Hemophilia Treatment and Research
- Protein Tyrosine Phosphatases
- Gene expression and cancer classification
- GABA and Rice Research
- Bioinformatics and Genomic Networks
- Functional Brain Connectivity Studies
- Pituitary Gland Disorders and Treatments
- Galectins and Cancer Biology
- Uterine Myomas and Treatments
- Pancreatic and Hepatic Oncology Research
- Phytochemicals and Antioxidant Activities
- Computational Drug Discovery Methods
- Estrogen and related hormone effects
- Cancer-related molecular mechanisms research
- Adrenal and Paraganglionic Tumors
- Mental Health Research Topics
- Pregnancy-related medical research
- Natural Products and Biological Research
- Natural Antidiabetic Agents Studies
- Complex Network Analysis Techniques
- Genomics, phytochemicals, and oxidative stress
- Lung Cancer Research Studies
- Viral-associated cancers and disorders
Union Hospital
2023-2025
Huazhong University of Science and Technology
2013-2025
Weatherford College
2024
Zhejiang Chinese Medical University
2023
Shanghai Chest Hospital
2019-2021
Shanghai Jiao Tong University
2021
Jinan Military General Hospital
2015
Union Hospital
2013
Southeast University
2008
Abstract Rosmarinic acid (RA) is a well-known phenolic widely present in over 160 species of herbal plants and known to exhibit anti-tumor effects on breast, prostate, colon cancers vitro. However, its effect mechanism gastric cancer liver are unclear. Moreover, there no RA report yet the chemical constituents Rubi Fructus (RF). In this study, was isolated from RF for first time, were evaluated using SGC-7901 HepG2 cells models. The treated with different concentrations (50, 75, 100 μg/mL)...
Pyroptosis plays a key role in the death of cells including cardiomyocytes, and it is associated with variety cardiovascular diseases. However, pyroptosis-related genes (PRGs) hypertrophic cardiomyopathy (HCM) not well characterized. This study aimed to identify biomarkers explore molecular mechanisms underlying functions PRGs HCM. The differentially expressed were identified by GEO2R, (DEPRGs) HCM combining PRGs. Enrichment analysis was performed using "clusterProfiler" package R software....
ER-β gene polymorphism and idiopathic thin endometrium confidence interval = 0.438 to 0.907, P 0.013).No significant difference in the genotype of AluI was found between two groups.The linkage disequilibrium RsaI haploids not either group, with D' values 0.2036 0.0685 patients controls, respectively.The results this study suggest a potential role polymorphisms etiology atrophic R allele as protective factor ethnic Han Chinese.
Recent progress in computational methods for inves-tigating physical and functional gene interactions has provided new insights into the complexity of biological processes. An essential part these is presented visually form interaction networks that can be valuable exploring mechanisms disease. Here, a combined network based on pairs with an extra layer re-liability was constructed after converting combining pair scores using novel algorithm across multiple approaches. Four groups kidney...
The use of novel tobacco products that do not burn leaves is becoming increasingly popular worldwide. In terms respiratory system, smoking damage to the epithelial cells lung in urgent need attention and research. this study, we produced combustion cigarettes (CC) condensate from conventional heated (HTP) heat-not-burn (HNB) tobacco, determine nicotine other ingredients content respectively assessment CC HTP cytotoxicity after acute exposure cigarette smoke. We further select a toxicological...
Motivation: To comprehend the brain microstructure of ASD patients, with or without Mental Retardation, and differentiate between them. Goal(s): This article aims to evaluate differences T1 T2 relaxometry in disease related regions for children ASD-MR , group, HC by using Synthetic MRI. Approach: MAGiC data were processed SyMRI create maps. Two pediatric radiologists outlined interest on these maps ITK-SNAP. Results: The left thalamus could be sensitive reflect microstructural change patient...
We propose a model for growing fractal networks based on the mechanisms learned from diffusion-limited aggregation (DLA) in geometries viewpoint of network. By studying DLA network, our introduces multiplicative growth, aging and geographical preferential attachment mechanisms, whereby featuring topological self-similar property hierarchical modularity. According to results theoretical analysis simulation, degree distribution proposed shows mixed (i.e., exponential algebraic distribution)...
Background: Primary lymphoepithelioma-like carcinoma (LELC) is a rare form of lung cancer, since genetic alternations participate in the carcinogenesis whether critical driver genes such as ROS1 fusion, anaplastic lymphoma kinase (ALK) rearrangement and epidermal growth factor receptor (EGFR) mutation play roles LELC remains unclear. Methods: We collected total 30 samples for prognosis analysis retrospectively ShangHai Chest Hospital, EGFR gene mutation, ALK fusion status were extracted from...