Background and objectives Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are rapidly spreading, posing a serious threat to the health of people worldwide, resulting in World Health Organization officially declaring it pandemic. There several biochemical markers linked predicting severity disease. This study aims identify most effective predictive biomarker such as C-reactive protein (CRP), ferritin, lactate dehydrogenase (LDH), procalcitonin (PCT), D-dimer,...

Background and Objectives: COVID-19 is a global pandemic. In our study, we aimed to utilize the hematological parameters in predicting prognosis mortality patients.Materials methods: A retrospective, observational study was conducted include all admitted patients (n = 191) having Polymerase chain reaction (PCR) positive, evaluated those for disease outcome by utilizing several biochemical markers.Results: Amongst ward versus intensive care unit (ICU), there were significant differences mean...

Introduction: Necrotizing fasciitis is a severe soft tissue infection that requires prompt surgical intervention, including extensive debridement. However, the optimal post-debridement wound care protocol remains debatable. Purpose: This study aimed to compare outcomes between patients who underwent serial debridement and those received daily dressings after Method: We retrospectively analyzed medical records from tertiary center over two years. Result: Our results suggest may offer superior...

Currently, there is a surge in the adoption of green construction practices (GCP) to address and attempt alleviate adverse effects activities on natural environment. The current research surrounding sustainability industry has witnessed notable efforts, primarily driven by growing consciousness environmental concerns. In this context, it worth noting that focus assessment schemes developed countries predominantly gravitated toward economic factors, with relatively less emphasis placed social...

Idiopathic inflammatory myopathies are an unusual group of with annual incidence 1 in 100 000 people the United States. Necrotizing autoimmune myopathy comprises only 16% this group. It usually presents severe proximal weakness, lower extremity and fatigue while very rarely does it present dysphagia respiratory muscle weakness. Statin use, cancer, connective tissue disorder usual associated risk factors. Anti-signal recognition particle 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 most...

Slipping rib syndrome is a rare cause of abdominal or lower chest pain that can remain undiagnosed for many years. Awareness among health care personnel this but significant disorder necessary early recognition. Prompt treatment avoid unnecessary testing, radiographic exposure, and years debilitating pain. A 52-year-old female was evaluated 3-year history recurrent Pain sharp, primarily located in the subcostal region left more than right, waxing waning, nonradiating, aggravates with...

Abstract Modern organic electronic and power devices gained attention due their superior performance efficiency with reduced cost. While nanocomposites of these semiconductors have high potential to further enhance properties. In this work, thin films zinc oxide-polyaniline (ZnO-PANI) nanocomposite different compositions ZnO (50, 60 70 wt%) are deposited by spin coater onto the surface p-Si. The phase identification samples is identified through x-ray diffraction analysis. Pure showed...

Background and objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for disease 2019 (COVID-19) pandemic. The mainly affects system of patient, in particular, lungs, which leads to patients presenting with distress failure, 5-15% requiring observation intensive care unit (ICU) support form ventilation. This study was aimed at identifying role biochemical markers risk stratification invasive non-invasive ventilation hospitalized COVID-19...

Acute pancreatitis is a disease with wide spectrum of severity, complications, and outcome severe life-threatening complications develop in patients leading to high mortality acute pancreatitis. The rationale this study diagnose the severity using single test ratio, i.e., CRP/albumin ratio which combination markers for systemic inflammation nutritional status. All those age group 16-80 years who were diagnosed admitted subsequently ICU included. Severe was determined as CT score above 7....

Sinking skin flap syndrome is rare phenomenon that occurs in patients with large craniectomies. Alteration normal anatomy and pathophysiology can result wide variety of symptoms including altered mental status, hemodynamic instability, dysautonomias. Management largely conservative. We here present a case patient craniectomy who was admitted to our hospital pneumonia. Later on, he developed worsening status CT head revealed sinking significant midline shift. This very neurological...

Task-specific ionic liquid dispersive liquid–liquid microextraction (TSIL-DLLME) is a simple and rapid preconcentration approach for the measurement of cadmium in serum blood samples human subjects. In this method novel task-specific liquid, trioctylmethyl ammonium thiosalicylate (TOMATS), which has dual characteristics as chelating agent extractive solvent, was investigated. TOMATS complexes with Cd due to effect ortho-positioned carboxylate relative thiol functionality. The assessment...

Congenital absence of left circumflex artery is a rare occurrence and very few cases have been reported in literature. It benign incidental finding; however some patients present with sudden onset chest pain mimicking acute coronary syndrome often resulting detection this anatomy on angiography. Coronary computed tomography angiography relatively new noninvasive imaging modality which can be used to confirm suspicion diagnose unique morphology reliably.

Takotsubo cardiomyopathy (TC) also known as broken heart syndrome or stress-induced is a relatively rare and transient form of cardiomyopathy. It usually mimics myocardial infarction in terms clinical electrocardiographic presentation, but coronary angiography does not reveal any evidence artery occlusion. Even though many underlying causes including emotional, physical physiological stress have been identified, the exact pathogenesis remains uncertain. Few anticancer therapies reported an...

Listeria monocytogenes is a gram-positive, rod-shaped organism that can cause serious infections such as meningitis, invasive gastroenteritis, and endocarditis. Every year 1600 people in the United States are affected, with significant mortality of 260 annually. gastroenteritis has third highest rate among all food-borne infection. Invasive listeriosis most commonly affect pregnant women, those extremes ages, comorbid diseases, weakened immune response. In this article, we present rare case...

Palbociclib is an FDA-approved cyclin-dependent kinase inhibitor to treat hormone-positive, HER2-negative metastatic breast cancer. Severe skin toxicities are rare but important adverse events associated with these agents. Early detection of severe forms lesions crucial permit the immediate discontinuation palbociclib in order avoid unacceptable risk level form cutaneous like Steven-Johnson Syndrome. In such cases, should be abruptly discontinued and early aggressive support initiated. We...

BACKGROUND: Esophageal cancer ranks eighth among the most prevalent cancers globally and is sixth leading cause of mortality from malignancy worldwide; it 7th in males 6th females. In Pakistan, incidence 4.1 per 100 000 with province Baluchistan having greatest incidence. OBJECTIVE: Report trends characteristics esophageal Pakistan over past 10 years. DESIGN: Cross-sectional, retrospective review medical records. SETTING: Tertiary care hospital. PATIENTS AND METHODS: The study included all...

Plasmablastic lymphoma (PBL) is a very rare disease and it usually considered human immunodeficiency virus (HIV)–related B-cell that carries poor prognosis. It mostly involves the oral cavity, lungs, nasal gastrointestinal tract, lymph node, skin. Therapeutic regimens like dose-adjusted etoposide, vincristine, doxorubicin, cyclophosphamide, prednisone (DA-EPOCH) have shown better results in these aggressive lymphomas. We report case of PBL an HIV-negative patient who presented to clinic with...

Introduction Acute pancreatitis is defined as inflammation of the pancreas. The body responds to by producing excessive neutrophils and causing programmed cell death lymphocytes. This leads immunological instability, which increases severity disease mortality rate. Recent data suggest that markers systemic are able predict prognosis various diseases. Our study aims assess acute in conjunction with these hematological inflammation. Materials methods was carried out emergency medicine...