A5083383435- Pregnancy and preeclampsia studies
- Natural Antidiabetic Agents Studies
- Adipose Tissue and Metabolism
- Nerve injury and regeneration
- Muscle Physiology and Disorders
- Autophagy in Disease and Therapy
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Reproductive System and Pregnancy
- Exercise and Physiological Responses
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Public Health and Nutrition
- Vitamin D Research Studies
- Pregnancy and Medication Impact
- Diabetes and associated disorders
- Sirtuins and Resveratrol in Medicine
- Diet and metabolism studies
Universidade de São Paulo
2019-2024
Universidade Federal de Mato Grosso
2015-2020
Although it is well established that a-calcitonin gene-related peptide (CGRP) stabilizes muscle-type cholinergic receptors nicotinic subunits (AChR), the underlying mechanism by which this neuropeptide regulates muscle protein metabolism and neuromuscular junction (NMJ) morphology unclear. To elucidate mechanisms how CGRP controls NMJ stability in denervated mice skeletal muscles, we carried out physiological, pharmacological, molecular analyses of atrophic muscles induced sciatic nerve...
Recent studies have shown that maternal vitamin D deficiency (VDD) causes long-term metabolic changes in offspring. However, little is known about the impact of VDD on offspring endocrine pancreas development and insulin secretion adult life male female animals. Female rats (Wistar Hannover) were fed either control (1000 IU Vitamin D3/kg), (0 or a Ca2+-enriched diet D3/kg + Ca2+ P/kg) for 6 weeks during gestation lactation. At weaning, status was confirmed based low serum calcidiol levels...
Abstract Background Exercise is commonly recommended to control hyperglycemia, including during pregnancy. We conducted this study understand the potential benefits and risks of exercise pregnancy women with diabetes. Specifically, we evaluated effects swimming on a diabetic rat assayed maternal‐fetal parameters. Methods Diabetes was induced in female newborn from Wistar rats by streptozotocin administration first postnatal day. At 110 days life, after confirm mild symptoms diabetes, were...
Calcitonin Gene-Related Peptide (CGRP) is a potent vasodilator peptide widely distributed in the central nervous system and various peripheral tissues, including cardiac muscle. However, its role heart protein metabolism remains unknown. We examined acute effects of CGRP on autophagy related signaling pathways mice cultured neonatal cardiomyocytes. (100 μg kg-1; s.c.) or 0.9 % saline was injected awake male C57B16 mice, metabolic profile determined up to 60 min. In fed drastically increased...
Resistance exercise (RE) training and pharmacological stimulation of β 2 -Adrenoceptors (β -ARs) alone can promote muscle hypertrophy prevent atrophy. Although the activation sympathetic nervous system (SNS) is a well-established response during RE, physiological contribution endogenous catecholamines -ARs to RE-induced changes on skeletal protein metabolism remains unclear. This study investigated effects blockade acute molecular responses induced by single bout RE in rodent muscles. Male...
Background: Limited studies have been carried out with prednisone (PRED) in treatment by glucose intolerant individuals, even this model the animals presented low blood levels at adulthood, high regenerative capacity of β-cell. Objective: The aim was to evaluate effects PRED mild diabetes on biochemical and immunological biomarkers. Methods: Rats were randomly divided into four groups: control (C), treated C+PRED (treatment 1.25 mg/Kg/day PRED); diabetic DM (mild diabetes) DM+PRED same dose...
Background Obesity is a pathophysiology condition that influences the metabolic pathways, and association with pregnancy can worsen lipidic glycemic profiles. Moreover, Duguetia furfuracea has been used for obesity also kidney disease treatment, however very few studies have conducted to verify its effectiveness safety using as well evaluate influence on profile.
Background Obesity is a pathophysiology that influences the metabolism, worsening lipidic and glycemic profiles, population search for alternatives to decrease its side effects. Duguetia furfuracea has been used obesity also kidney disease treatment, however very few studies have conducted verify effectiveness safety using as well evaluate influence on metabolic profile.