A5024317083- Adipose Tissue and Metabolism
- Birth, Development, and Health
- Vitamin D Research Studies
- Animal Nutrition and Physiology
- Stress Responses and Cortisol
- Gestational Diabetes Research and Management
- Science and Education Research
- Menopause: Health Impacts and Treatments
- Nutrition, Genetics, and Disease
- Lipid metabolism and biosynthesis
- Autophagy in Disease and Therapy
- Pancreatic function and diabetes
- Cancer, Lipids, and Metabolism
- Diet and metabolism studies
- Heavy Metals in Plants
- Livestock and Poultry Management
- Mitochondrial Function and Pathology
- Heavy metals in environment
- Sirtuins and Resveratrol in Medicine
- Meat and Animal Product Quality
- Hormonal and reproductive studies
- Olfactory and Sensory Function Studies
- Sex and Gender in Healthcare
- Muscle metabolism and nutrition
- Medicinal Plants and Neuroprotection
Universidade de São Paulo
2020-2024
Universidade de Ribeirão Preto
2021
Universidade Federal de Viçosa
2010
Sex hormone-induced cardiovascular events are important undesirable effects in transgender people under GAHT. Studies addressing the impact of GAHT will certainly contribute to improve healthcare services offered this population. Our study showing that vascular dysfunction, via Th17 cell-related mechanisms, precedes increased blood pressure induced by testosterone a mouse model, reveals potential mechanisms involved GAHT-related and may provide new markers/targets for clinical practices...
Abstract Background Fetal stage is a critical developmental window for the skeletal muscle, but little information available about impact of maternal vitamin D (Vit. D) deficiency (VDD) on offspring lean mass development in adult life male and female animals. Methods Female rats (Wistar Hannover) were fed either control (1000 IU Vit. D3/kg) or VDD diet (0 6 weeks during gestation lactation. At weaning, randomly separated received standard up to 180 days old. Results Vitamin induced muscle...
Recent studies have shown that maternal vitamin D deficiency (VDD) causes long-term metabolic changes in offspring. However, little is known about the impact of VDD on offspring endocrine pancreas development and insulin secretion adult life male female animals. Female rats (Wistar Hannover) were fed either control (1000 IU Vitamin D3/kg), (0 or a Ca2+-enriched diet D3/kg + Ca2+ P/kg) for 6 weeks during gestation lactation. At weaning, status was confirmed based low serum calcidiol levels...
Este estudo foi realizado para avaliar os efeitos da redução do nível de proteína bruta (PB) ração com suplementação aminoácidos sintéticos sobre o desempenho e rendimento carcaça frangos corte 22 a 42 dias idade mantidos sob estresse por calor. Utilizaram-se 280 machos linhagem Cobb 500 peso inicial 856 ± 7,41 g, distribuídos em delineamentointeiramente casualizado, cinco níveis PB (21,6; 20,6; 19,6; 18,6 ou 17,6%), oito repetições sete aves unidade experimental. A temperatura no interior...
O experimento foi conduzido com objetivo de avaliar o efeito da adição cromo orgânico (Cr) na alimentação codornas japonesas fase inicial postura mantidas em estresse por calor. Seiscentas 63 dias idade e peso 158,6 g foram ambiente alta temperatura (32ºC) alimentadas dietas à base milho farelo soja suplementadas Cr (cromo-metionina) substituição ao inerte (0, 500, 1.000, 1.500 2.000 ppb). delineamento utilizado inteiramente casualizado, cinco tratamentos, 12 repetições dez aves unidade...
The sympathetic nervous system (SNS) activates cAMP signaling and promotes trophic effects on brown adipose tissue (BAT) through poorly understood mechanisms. Because norepinephrine has been found to induce antiproteolytic muscle heart, we hypothesized that the SNS could inhibit autophagy in interscapular BAT (IBAT). Here, describe selective denervation of rat IBAT kept at 25°C induced atrophy, parallel dephosphorylated forkhead box class O (FoxO), increased cathepsin activity, autophagic...
Although it is well established that glucocorticoids inactivate thermogenesis and promote lipid accumulation in interscapular brown adipose tissue (IBAT), the underlying mechanisms remain unknown. We found dexamethasone treatment (1 mg/kg) for 7 days rats decreased IBAT thermogenic activity, evidenced by its lower responsiveness to noradrenaline injection associated with reduced content of mitochondrial proteins, respiratory chain protein complexes, noradrenaline, β3 -adrenergic receptor. In...
Objective To analyze the impact of maternal Vitamin D deficiency (VDD) on offspring muscle development in adulthood male and female rats. Methods Twelve 5‐week‐old Wistar Hannover rats were fed either a Vit. D3 + diet (AIN93G with 1000 IU vitamin D3/kg diet) or − without D3) for six weeks then bred to Mothers maintained diets throughout gestation lactation. At weaning, offsprings separated four groups: control (M‐CTRL F‐CTRL, respectively) pups dams diet; VDD (M‐VDD F‐VDD, diet. Offspring...
Introdução. Dexametasona (DEX) é um glicocorticóide sintético com ação anti-inflamatória utilizado no tratamento de muitas doenças como artrite reumatoide, asma, alergias e autoimunes. Estudos mostram que a DEX pode causar deficits cognitivos em animais, podendo estar relacionada redução na atividade exploratória, prejuízo aprendizagem memória espacial aumento da ansiedade. Objetivo. O presente estudo investigou os efeitos sobre ansiedade ratos jovens. Método. Ratos Wistar machos foram...