A5078552586- Muscle Physiology and Disorders
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Genetics and Physical Performance
- Body Composition Measurement Techniques
- Cardiovascular and exercise physiology
- Diet and metabolism studies
- Laser Applications in Dentistry and Medicine
- Neurological and metabolic disorders
- Sports Performance and Training
- Exercise and Physiological Responses
- Tendon Structure and Treatment
- Healthcare Regulation
- Acupuncture Treatment Research Studies
- Infrared Thermography in Medicine
- Periodontal Regeneration and Treatments
- Systemic Sclerosis and Related Diseases
- Diet, Metabolism, and Disease
- Knee injuries and reconstruction techniques
- Physical Education and Gymnastics
- Quality and Supply Management
- Osteoarthritis Treatment and Mechanisms
- Business and Management Studies
- Endoplasmic Reticulum Stress and Disease
- Outsourcing and Supply Chain Management
University of Houston
2022-2024
Universidade de São Paulo
2016-2023
Pharmac
2023
Universidade Estadual Paulista (Unesp)
2012-2019
Universidade Paulista
2018
Universidade do Oeste Paulista
2017
Hospital Regional de Presidente Prudente
2013-2016
Laboratoire des Sciences pour la Conception, l'Optimisation et la Production
2005
Abstract Skeletal muscle regeneration involves a signaling network that regulates the proliferation, differentiation, and fusion of precursor cells to injured myofibers. IRE1α, one arms unfolded protein response, cellular proteostasis in response ER stress. Here, we demonstrate inducible deletion IRE1α satellite mice impairs skeletal through inhibiting myoblast fusion. Knockdown or its downstream target, X-box 1 (XBP1), also inhibits during myogenesis. Transcriptome analysis revealed...
Abstract Background Fetal stage is a critical developmental window for the skeletal muscle, but little information available about impact of maternal vitamin D (Vit. D) deficiency (VDD) on offspring lean mass development in adult life male and female animals. Methods Female rats (Wistar Hannover) were fed either control (1000 IU Vit. D3/kg) or VDD diet (0 6 weeks during gestation lactation. At weaning, randomly separated received standard up to 180 days old. Results Vitamin induced muscle...
It has been suggested that the proliferation and early differentiation of myoblasts are impaired in Marfan syndrome (MFS) mice during muscle regeneration. However, underlying cellular molecular mechanisms remain poorly understood. Here, we investigated regeneration MFS mouse models by analyzing influence fibrotic niche on satellite cell function.
Skeletal muscle regeneration involves coordinated activation of an array signaling pathways. Fibroblast growth factor-inducible 14 (Fn14) is a bona fide receptor for the TWEAK cytokine. Levels Fn14 are increased in skeletal mice after injury. However, cell-autonomous role remains unknown. Here, we demonstrate that global deletion attenuates regeneration. Conditional ablation myoblasts but not differentiated myofibers inhibits promotes myoblast fusion without affecting levels myogenic...
The aim of this study was to analyze changes in the skeletal muscle tissue rats after stretch injury using fractal analysis.Nineteen were divided into three groups, Control (n= 5) (C), Lesion two days 7) (L2), and seven (L7).Histological slides gastrocnemius animals prepared stained with Hematoxylin eosin for analysis inflammatory process, picrosirius demonstration collagen.The subsequently analyzed Fractal Dimension (FD).The results showed high FD values process experimental groups L2 L7...
Skeletal muscle atrophy is a prevalent complication in multiple chronic diseases and disuse conditions. Fibroblast growth factor-inducible 14 (Fn14) member of the TNF receptor superfamily bona fide TWEAK cytokine. Accumulating evidence suggests that Fn14 levels are increased catabolic conditions as well during exercise. However, role regulation skeletal mass function remains poorly understood. In this study, through generation novel muscle-specific Fn14-knockout mice, we have investigated...
To describe the effects of immobilization, free remobilization and by physical exercise about mechanical properties skeletal muscle rats two age groups.56 Wistar divided into groups according to age, an adult group (five months) older (15 months). These were subdivided in: control, immobilized, remobilized exercise. The pelvic limb was immobilized for seven days. protocol consisted five swimming sessions, once per day 25 minutes session. gastrocnemius subjected tensile tests, evaluated...
A presente pesquisa visou estudar os efeitos da remobilização por meio de exercício físico sobre o tecido ósseo ratos adultos e idosos.Foram utilizados 80 Wistar machos divididos em dois grupos, com idade cinco meses para 15 idosos; subdivididos quatro subgrupos cada: grupo controle (G1 G5), imobilizado (G2 G6), remobilizado livre (G3 G7), (G4 G8).Os grupos imobilizados foram eutanasiados logo após a retirada imobilização gessada, que perdurou 14 dias.Os remobilizados permaneceram sete dias...
A sample of 39 rats were divided into the following groups: baseline (BL); aerobic training (ET4 and ET8); anaerobic (ST4 ST8); concurrent (CT4 CT8). The was performed by swimming with a load corresponding to 70% threshold; jumping in water 50% body weight; combined two protocols. analysis BMDwas on tibia animals showed an increase density ST4, CT4, ET8, ST8, CT8 groups when compared both BL ET4. Thus, it is concluded that exercise shown be effective increasing BMD afterfour weeks training;...
ABSTRACT Introduction: Immobilization is a treatment technique often used to reduce pain and prevent worsening of the injury. However, it promotes harmful effects on musculoskeletal tissue, resulting in marked loss muscle function, which may be aggravated elderly. Physical exercise an important intervention mitigate these effects. Objective: To analyze possible morphometric changes gastrocnemius rats after immobilization remobilization with physical exercise. Methods: Fifty-six were divided...
The aim of the present study was to observe changes in muscle tissue rats after application growth hormone (GH) and performing a strength training protocol (ST).In total, 40 male Wistar rats, 60 days old, were used, divided into four groups: control (C), GH (GHC), (T), with (GHT).The physical (PT) composed series 10 jumps water, 3x/week, an overload 50 % body weight for weeks.GH administered intraperitoneally at dose 0.2 IU/Kg GHC GHT groups saline (0.9 sodium chloride) C T groups.After...
The objective of this study was to investigate the alterations in morphology and aerobic resistance rats subjected different physical training protocols. consisted 55 âWistarâ breed, 100 days age, over a period 8 weeks. animals were randomly distributed between four groups: control (CTLE); neuromuscular anaerobic (TAN); (TAE) concurrent (TCc). After weeks, some euthanized. body mass index (BMI), Lee (Lee), epididymal adipose tissue (TecAdp), weight, feed efficiency ratio (CoefAlim)...
PEDro, PubMed e SciELO, o período de publicação dos estudos foi 2008 à 2013.Dentre os artigos encontrados, realizada uma análise nos títulos resumos, visando confirmar se encontravam critérios seleção estabelecidos; deveriam ser originais; não revisões sistemáticas.Os achados mostraram que a utilização dieta adequada exercícios
To analyze the effects of concurrent training (CT) on muscle fibers Wistar rats submitted to standard and hypercaloric diets.In total, 40 were used, divided into 4 groups: Sedentary Group (GS); Exercise (GE), Obese (OS) (OE).The animals performed a CT protocol consisting of: strength aerobic training, carried out 3 times week for 45 days.The smallest diameter (MDF) was analyzed evaluate hypertrophy.It observed that OE group presented significant decrease in MDF, compared OS (OE=77.41µm vs....
The aim of this study was to analyze the effects an association cryotherapy and therapeutic ultrasound on treatment muscle injured by impact.Fifty-five Wistar rats were divided into five groups (n = 11), Acute Injury (AI), (I), Cryotherapy (CR), Therapeutic Ultrasound (TU) Association (CRTU).The CR CRTU received applications three times (immediately, 24 48 h after injury) 20 minutes duration.The TU for seven days, minutes, in pulsed mode, 0.5 w/cm intensity, frequency 1 MHz.Body mass...
Muscular dystrophies make up a group of genetic neuromuscular disorders that involve severe muscle wasting. TGF-β-activated kinase 1 (TAK1) is an important signaling protein regulates cell survival, growth, and inflammation. TAK1 has been recently found to promote myofiber growth in the skeletal adult mice. However, role diseases remains poorly understood. In present study, we have investigated how affects progression dystrophic phenotype mdx mouse model Duchenne muscular dystrophy (DMD)....
Abstract Muscular dystrophy is a group of genetic neuromuscular disorders that involves severe muscle wasting. Transforming growth factor β-activated kinase 1 (TAK1) an important signaling protein regulates cell survival, growth, and inflammation. TAK1 has been recently found to promote myofiber in skeletal adult mice. However, the role remains poorly understood. In present study, we have investigated how affects progression dystrophic phenotype mdx mouse model Duchnne muscular (DMD). highly...