A5103110589- Animal Nutrition and Physiology
- Anesthesia and Neurotoxicity Research
- Phytochemical Studies and Bioactivities
- Selenium in Biological Systems
- Phytochemistry and biological activity of medicinal plants
- Sunflower and Safflower Cultivation
- Pharmacological Effects of Natural Compounds
- Ubiquitin and proteasome pathways
- Genetic Mapping and Diversity in Plants and Animals
- Thermal Regulation in Medicine
- Traditional Chinese Medicine Studies
- High Altitude and Hypoxia
- Glass properties and applications
- Immune Response and Inflammation
- Primate Behavior and Ecology
- High-Temperature Coating Behaviors
- Heat shock proteins research
- Eicosanoids and Hypertension Pharmacology
- Aldose Reductase and Taurine
- Phytoestrogen effects and research
- Phytochemistry and Bioactive Compounds
- Pharmacological Effects of Medicinal Plants
- Tumors and Oncological Cases
- Histiocytic Disorders and Treatments
- Biological Research and Disease Studies
Sanya Central Hospital
2024
Hunan University
2024
Huazhong University of Science and Technology
2023
Air Force Medical University
2006-2021
Northeast Agricultural University
2017-2021
Zhongda Hospital Southeast University
2017-2019
Ministry of Agriculture
2017
Education Department of Heilongjiang Province
2017
Guangdong General Hospital
2015
Guangdong Academy of Medical Sciences
2015
Some studies have demonstrated dexmedetomidine has anti-inflammatory effect on septic rats. However, the mechanism of how exerts these effects is still remained unknown. This study was designed to investigate inhibits production inflammatory mediators in cecal ligation and puncturinduced rats.48 Sprague-Dawley rats were randomly divided into six groups: sham-operated (sham) group, puncture (CLP) 5 μg/kg (DEX5) 10 (DEX10) group,dexmedetomidine + yohimbine (DEX10 Yoh) group yohimibine (Yoh)....
Oxidative stress plays an important role in the initiation and development of myocardial injury (MI). The peroxisome proliferator-activated receptor gamma coactivator-1α (PGC‑1α)/nuclear factor erythroid 2-related 2 (Nrf2) pathway is considered to be a potential target for cardioprotection MI. Acetyl-11-keto-β-boswellic acid (AKBA) major organic component extracted from Boswellia serrata Roxb. ex Colebr. Hydroxysafflor yellow A (HSYA) principal active constituent Carthamus tinctorius L. In...
Extracellular vesicles (EVs) play an important role in human and bovine milk composition. According to excellent published studies, it also exerts various functions the gut, bone, or immune system. However, effects of milk-derived EVs on skeletal muscle growth performance have yet be fully explored. Firstly, current study examined amino acids profile (HME) (BME) using targeted metabolomics. Secondly, HME BME were injected quadriceps mice for four weeks (1 time/3 days). Then, related...
Aim. To investigate the effect of Furostanol Saponins from Allium Macrostemon Bunge Bulbs (FSAMB) on platelet aggregation rate rats with coronary heart disease and discuss mechanism FSAMB affecting through PI3K/Akt pathway. We established rat models (CHD) prepared platelet-rich plasma. The different concentrations in SD induced by ADP was observed vitro vivo. And Lactate Dehydrogenase (LDH), Creatine Kinase-MB Form (CK-MB), Cardiac Troponin I (cTnI) are detected blood to know level damage...
Large amounts of fat deposition often lead to loss reproductive efficiency in humans and animals. We used broiler chickens as a model species conduct two-directional selection for against abdominal over 19 generations, which resulted lean line. Direct content also indirectly significant differences (P < 0.05) testis weight (TeW) TeW percentage total body (TeP) between the lines.A 475 individuals from generation 11 (G11) were genotyped. Genome-wide association studies revealed two regions on...
Altering the content of an alloying element in alloy materials will inevitably affect other elements, while effect is frequently disregarded, leading to subsequent negligence common influence on physical properties alloys. Therefore, correlation between elements and has not been adequately addressed existing studies. In response this problem, present study focuses Al10Ti15Nix1Crx2Cox3 alloys investigates competitive interplay among Ni, Cr, Co formation through a single-element (SE) analysis...
Esophageal squamous cell carcinomas (ESCCs) are highly invasive and have poor prognoses. We investigated the role of PTPLAD2, a protein tyrosine phosphatase‐like A domain (PTPLAD) family member, in ESCC carcinogenesis. Survival analysis was performed using patient data. tissue samples lost PTPLAD2 heterozygosity had decreased expression. Low expression high p‐STAT3 correlated with prognosis. Overexpression cells reduced STAT3 phosphorylation, FoxM1, inhibited proliferation mouse xenograft...
The nephrotoxicity of gentamicin (GM) has been widely recognized. Heat shock protein 72 (HSP72) reported to be a cytoprotectant. However, its cytoprotective effect against GM induced kidney injury not yet studied. In this study, we investigated the HSP72 on GM-induced in vitro. Human Kidney tubular cell line, HK-2 cells were divided into four groups: control group, group (cells incubated with only), heat (HS) at 43 degrees C for 30 min), and plus HS respectively. Lactate dehydrogenase (LDH)...
Potential toxicity of CoQ(10) was studied in rats by oral gavage for 90 days at 500, 1500, and 3000 mg/kg.day. A 15-day recovery period after the administration investigated. Body weight food consumption were measured throughout study. Meanwhile, clinical observations recorded. Hematological blood chemistry parameters evaluated both end dosing period. Gross-pathologic histopathologic examination performed on select tissues from all animals. No adverse changes mortality signs occurred. The...
To evaluate the effect of Guizhi Gancao Longgu Muli Tang (GGLMT), a decoction prepared with herbal medicine Traditional Chinese Medicine, on sleep disturbances in women menopause. Totally 162 participants were recruited for treatment difficulty from February, 2012 to December, 2014. Decoction 200 mL was taken by every participant twice daily half an hour after lunch and dinner during two weeks. Sleep quality assessed Pittsburg index (PSQI) menopausal symptoms life evaluated menopause rating...
Efficient regulation of activator site occupation is crucial for developing white light phosphors with excellent luminous properties. Herein, we report the synthesis new borophosphate K2BaSr(PO4)2-x(BO3)x:0.04Eu2+ via an anion...
Background: Tuberous sclerosis complex (TSC) is a rare autosomal-dominant disorder involving multiple organs including skin, brain, heart, lung, kidney and liver. It usually occurs as early birth or even in utero, with cases diagnosed their adulthood. Here, we present adult case of TSC presenting periungual fibromas (PF). Case Presentation: A 67-year-old gentleman showed recurrence polypoid tumors on all the toes right foot when to our department. On physical examination, there were...
Objective: Wild-type p53-induced phosphatase (Wip1) is known as an oncogene and associated with development of various types human cancers. However, the expression role Wip1 in bladder transitional cell carcinoma (TCC) remains unclear.