Zhonghua Hu

ORCID: 0000-0002-0117-7081
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About
Contact & Profiles
Research Areas
  • Space Satellite Systems and Control
  • Astro and Planetary Science
  • Supercapacitor Materials and Fabrication
  • Mesoporous Materials and Catalysis
  • MicroRNA in disease regulation
  • Neuroscience and Neuropharmacology Research
  • Planetary Science and Exploration
  • Soft Robotics and Applications
  • Geotechnical Engineering and Underground Structures
  • Advancements in Battery Materials
  • Sepsis Diagnosis and Treatment
  • RNA Research and Splicing
  • Landslides and related hazards
  • Adsorption and biosorption for pollutant removal
  • Advanced Battery Materials and Technologies
  • Genetics and Neurodevelopmental Disorders
  • Robotic Path Planning Algorithms
  • Nonlinear Photonic Systems
  • Robot Manipulation and Learning
  • Advanced Fiber Laser Technologies
  • Rock Mechanics and Modeling
  • Catalytic Processes in Materials Science
  • Zeolite Catalysis and Synthesis
  • Robotic Mechanisms and Dynamics
  • Monoclonal and Polyclonal Antibodies Research

East China Jiaotong University
2022-2025

Xiangya Hospital Central South University
2019-2024

Central South University
2019-2024

Weatherford College
2024

China Medical University
2024

Hangzhou First People's Hospital
2024

Tianjin University
2020-2023

Jiangxi Agricultural University
2022-2023

Wuhan Textile University
2022-2023

Third Xiangya Hospital
2020-2023

10.1016/s1383-5866(02)00149-1 article EN Separation and Purification Technology 2003-03-04

Background: Homed-based exercise training via telehealth is an effective method for cardiac rehabilitation in patients with heart failure (HF). However, little known about the effects of among HF China. Design: A randomized controlled design repeated measures was adopted this study. Objective: To examine effect our program on health outcomes Methods: total 98 participants were randomly allocated to experimental group (n = 49) and control from January 2014 February 2015 a teaching hospital...

10.1097/md.0000000000012069 article EN cc-by-nc Medicine 2018-08-01

Long-term potentiation (LTP) is a form of synaptic plasticity that results in enhanced strength. It associated with the formation and enlargement dendritic spines-tiny protrusions accommodating excitatory synapses. Both LTP spine remodelling are crucial for brain development, cognition pathophysiology neurological disorders. The role microRNAs (miRNAs) maintenance LTP, however, not well understood. Using next-generation sequencing to profile miRNA transcriptomes, we demonstrate miR-26a...

10.1038/ncomms7789 article EN cc-by Nature Communications 2015-04-10

Dynamic change of mitochondrial morphology and distribution along neuronal branches are essential for neural circuitry formation synaptic efficacy. However, the underlying mechanism remains elusive. We show here that Pink1 knockout (KO) mice display defective dendritic spine maturation, reduced axonal vesicles, abnormal connection, attenuated long-term potentiation (LTP). Drp1 activation via S616 phosphorylation rescues deficits maturation in KO neurons. Notably, harboring a knockin (KI)...

10.1038/s41392-022-00933-z article EN cc-by Signal Transduction and Targeted Therapy 2022-04-15

We investigate the propagation and interaction dynamics of optical dark bound solitons for defocusing Lakshmanan-Porsezian-Daniel equation, which is a physically relevant generalization nonlinear Schrödinger equation involving higher-order effects. Explicit N-dark soliton solutions in compact determinant form are constructed via binary Darboux transformation method. Bound states discussed when incoherent have same velocity. find an interesting phenomenon that molecules double-valley (DVDSs)...

10.1364/oe.473024 article EN cc-by Optics Express 2022-10-14

Traumatic brain injury (TBI) is a leading cause of injury-related death and disability worldwide. Effective treatment for TBI limited many patients suffer from neuropsychiatric sequelae. The molecular cellular mechanisms underlying the neuronal damage impairment mental abilities following are largely unknown. Here we used next generation sequencing platform to delineate miRNA transcriptome changes in hippocampus at 24 hours 7 days rat controlled cortical impact (CCI) model, developed...

10.1371/journal.pone.0039357 article EN cc-by PLoS ONE 2012-06-22

The number of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) in synapses determines synaptic strength. AMPAR expression can be regulated locally dendrites by activity. mechanisms activity-dependent local regulation expression, however, remain unclear. Here, we tested whether microRNAs (miRNAs) are involved N-methyl-d-aspartate (NMDA) receptor (NMDAR)–dependent expression. We used the 3′ untranslated region Gria1, which encodes AMPA subunit GluA1, to pull down miRNAs...

10.1083/jcb.201404092 article EN The Journal of Cell Biology 2015-03-23

Two broad theories of visual working memory (VWM) storage have emerged from current research, a discrete slot-based theory and continuous resource theory. However, neither the or clearly stipulates how mental commodity for VWM (discrete slot resource) is allocated. Allocation may be based on number items via stimulus-driven factors, it task demands voluntary control. Previous studies obtained conflicting results regarding automaticity versus controllability such allocation. In study, we...

10.1037/xlm0000376 article EN other-oa Journal of Experimental Psychology Learning Memory and Cognition 2017-03-02

The growing amount of space debris poses a threat to operational spacecraft and the long-term sustainability activities in outer space. According orbital mechanics, an uncontrolled object will be tumbling, bringing great challenge capture remove it. In this paper, dual-arm coordinated “Area-Oriented Capture” (AOC) method is proposed non-cooperative tumbling target. Firstly, motion equation target established, based on which, dynamic properties are analyzed. Then, concept presented deal with...

10.1016/j.cja.2019.03.018 article EN cc-by-nc-nd Chinese Journal of Aeronautics 2019-03-21
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