- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Herpesvirus Infections and Treatments
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Endometriosis Research and Treatment
- Effects of Environmental Stressors on Livestock
- Hydrogen's biological and therapeutic effects
- Healthcare and Venom Research
- Eosinophilic Esophagitis
- Renal Diseases and Glomerulopathies
- Blood groups and transfusion
- Milk Quality and Mastitis in Dairy Cows
- Reproductive System and Pregnancy
- Animal Genetics and Reproduction
- Biliary and Gastrointestinal Fistulas
- Liver Disease and Transplantation
- Gastrointestinal Bleeding Diagnosis and Treatment
SingHealth
2022-2023
Sengkang General Hospital
2022-2023
Kyushu University
2020
Zhengzhou People's Hospital
2015
University of South Florida
2013-2014
Moffitt Cancer Center
2013-2014
Brown University
2010-2013
Hospital of Hebei Province
2013
First Hospital of Shijiazhuang
2013
Rhode Island Hospital
2011-2012
ABSTRACT Herpesviruses utilize different origins of replication during lytic versus latent infection. Latent DNA depends on host cellular machinery, whereas cycle requires virally encoded proteins. In replication, the origin ( ori-Lyt ) is bound by a virus-specified binding protein (OBP) that recruits core machinery. this report, we demonstrated sequences in two noncoding regions Kaposi's sarcoma-associated herpesvirus (KSHV) genome, between open reading frames (ORFs) K4.2 and K5 K12 ORF71,...
Ageing of the uterine endometrium is a critical factor that affects reproductive success, but mechanisms associated with ageing are unclear. In this study, we conducted qualitative examination age-related changes in endometrial tissues and identified candidate genes as markers for ageing. Gene expression patterns were assessed by two RNA-sequencing experiments using from wild type (WT) C57BL/6 mice. data obtained validated real-time PCR. Genes expressing pro-inflammatory cytokines Il17rb...
The goal of this study was to determine the luminal recurrence rate asymptomatic patients undergoing annual surveillance esophagogastroduodenoscopy (EGD).Current guidelines recommend EGD in postesophagectomy with esophageal cancer if there is clinical suspicion local recurrence. However, many undergo despite recommendations contrary.A query performed all who underwent esophagectomy between January 2000 and April 2010 at Moffitt Cancer Center. Patients were included if: they curative intent,...
Purpose: A 53 year old veteran underwent colonoscopy to evaluate a positive fecal occult blood test. The endoscopy revealed eight dimunitive polyps in the transverse, descending, and sigmoid colon, excised by cold biopsy, two one centimeter removed snare cautery. procedure was uneventful patient felt well remainder of day. following morning, he awoken severe left sided abdominal pain developed vomiting. He presented ED with worsening his symptoms found have WBC 15.9 HgB 8.5 (down from 13.8)...
Purpose: Introduction: The differential diagnosis for hemorrhagic ascites is limited; however, in women of child bearing age this must include endometriosis. Case Presentation: A 26 year-old nulliparous Nigerian woman presented with symptoms abdominal distention and recurrent 2 years. Paracentesis revealed the following: WBC 200, Lymph 22%, RBC 660,000, SAAG 1.3, total protein 4 g/dL, LDH >1000 IU/mL, glucose <3 mg/dL, normal amylase triglyceride. Cytology was negative malignancy. Culture...
Purpose: Introduction: Use of antiviral therapy in pregnancy is controversial and many experts advocate the discontinuation as soon confirmed for fear fetal toxicity. This strategy not without risks. We present a case patient on with acute liver failure after withdrawal therapy. Case Presentation: 28-year-old Cambodian woman chronic HepBsAg + HBV infection high viral load. Liver biopsy showed inflammation (grade 1/4) mild fibrosis (stage 2/4). She was started entecavir normalization LFT...
Purpose: Introduction: Many carcinoid tumors are found incidentally at the time of endoscopy. We present first case report tumor associated with gastric heterotopia in duodenum. A 66-year-old man longstanding history gastroesophageal reflux disease was referred for an upper endoscopy to rule out Barrett's disease. His symptoms had been controlled on daily PPI and he denied having any dysphagia, nausea, vomiting, or weight loss. On review systems, diarrhea facial flushing. He otherwise good...
Introduction: Familial adenomatous polyposis (FAP) represents about 1% of all colon cancer and is caused by germline mutations in the coli (APC) gene. The clinical manifestation includes classic FAP, attenuated FAP (AFAP), Gardner Syndrome Turcot Syndrome. We present a patient with newly diagnosed AFAP due to new variant resulting substitution valine for isoleucine at amino acid position 1746 (I1746V) APC protein. Case Presentation: This 52-year-old woman past medical history significant...