Hiroyuki Tomari

ORCID: 0000-0001-8085-4214
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Reproductive Health and Technologies
  • Sperm and Testicular Function
  • Prenatal Screening and Diagnostics
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive System and Pregnancy
  • Ovarian function and disorders
  • Renal and related cancers
  • Pregnancy and preeclampsia studies
  • Preterm Birth and Chorioamnionitis
  • Endometriosis Research and Treatment
  • Congenital Anomalies and Fetal Surgery
  • Estrogen and related hormone effects
  • Renal Diseases and Glomerulopathies
  • Genetic Syndromes and Imprinting
  • Genetic and Kidney Cyst Diseases

Kyushu University
2020

Ono Clinic
2011

Abstract Purpose To investigate the relationship between meiotic spindle size in human metaphase II oocytes and embryo developmental potential after intracytoplasmic sperm injection ( ICSI ). Methods Analyzed were 1302 with a visible from 281 patients aged under 40 years undergoing cycles. The was imaged by using PolScope before . classified into three groups, according to size: group A (<90 μm 2 ), B (90‐120 C (>120 Results Overall, 389 (29.9%) A, 662 (50.8%) B, 251 (19.3%) C....

10.1002/rmb2.12100 article EN cc-by-nc Reproductive Medicine and Biology 2018-04-10

Abstract Successful assisted reproductive technology pregnancy depends on the viability of embryos and endometrial receptivity. However, literature has neglected effects environment during proliferative phase implantation success or failure. Human stromal cells (hESCs) were isolated from tissues sampled at oocyte retrieval women undergoing infertility treatment. Primary hESC cultures used to investigate relationship between stemness senescence induction in this population embryo Patients...

10.1093/biolre/ioaa044 article EN cc-by-nc Biology of Reproduction 2020-04-14

Ageing of the uterine endometrium is a critical factor that affects reproductive success, but mechanisms associated with ageing are unclear. In this study, we conducted qualitative examination age-related changes in endometrial tissues and identified candidate genes as markers for ageing. Gene expression patterns were assessed by two RNA-sequencing experiments using from wild type (WT) C57BL/6 mice. data obtained validated real-time PCR. Genes expressing pro-inflammatory cytokines Il17rb...

10.1093/molehr/gaaa078 article EN Molecular Human Reproduction 2020-11-18

To investigate the actual status of fertility preservation techniques in oncofertility Japan and to clarify involvement embryologists this field.

10.1089/jayao.2024.0032 article EN Journal of Adolescent and Young Adult Oncology 2024-11-18

Abstract Study question Does endometrial stimulation with culture medium containing granulocyte macrophage colony-stimulating factor (GM-CSF) promote implantation potential of vitrified-warmed blastocysts? Summary answer Endometrial GM-CSF prior to transfer blastocysts may embryo and improve pregnancy continuation. What is known already Human embryonic development in vivo precisely regulated by various cytokines, including growth factors. a cytokine that plays an important role reproductive...

10.1093/humrep/dead093.816 article EN Human Reproduction 2023-06-01

Background and Aims: Physiologic ICSI (PICSI) is a method of in which sperm attached to hyaluronic acid (HA) are selected. It known that mature express receptors for adhesion the HA due reconstruction protoplasmic membrane. In fact, it has been confirmed can adhere sperm, reported their DNA highly normal. However, previous studies on clinical outcomes PICSI have shown inconsistent results. Therefore, purpose this study was evaluate usefulness using sibling oocytes. Method: The 365 cycles two...

10.1142/s2661318223744090 article EN cc-by-nc-nd Fertility & Reproduction 2023-12-01

10.1016/j.fertnstert.2006.07.541 article EN publisher-specific-oa Fertility and Sterility 2006-09-01
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