- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Oral Health Pathology and Treatment
- Immune responses and vaccinations
- Bacteriophages and microbial interactions
- Vitamin C and Antioxidants Research
- Long-Term Effects of COVID-19
- Viral gastroenteritis research and epidemiology
- Salivary Gland Disorders and Functions
- Facial Nerve Paralysis Treatment and Research
- COVID-19 Clinical Research Studies
Jeonbuk National University
2021-2023
Chonbuk National University Hospital
2021
The upper respiratory tract is compromised in the early period of COVID-19, but SARS-CoV-2 tropism at cellular level not fully defined. Unlike recent single-cell RNA-Seq analyses indicating uniformly low mRNA expression entry–related host molecules all nasal epithelial cells, we show that protein levels are relatively high and their localizations restricted to apical side multiciliated cells. In addition, provide evidence patients with COVID-19 massively detected replicated within We...
Background: As many SARS-CoV-2 infections are asymptomatic, it could be useful to able determine how much time has passed since infection. We explored the changes in temporal levels of T cell-related proteins (including perforin and granzymes) sera patients with infection using a commercially available assay. Methods: This study enrolled 36 infected 20 healthy control participants. Blood samples were collected at three different times based on number days symptom onset (early phase: 1–5...
As SARS-CoV-2 variants of concern emerged, the genome sequencing strains became more important. In this study, was sequenced using amplicon-based with MinION. The primer panel used in study consisted only 11 panels and size amplicons approximately 3 kb. Full sequences were obtained a hundred copies genome, 92.33% 75.39% 10 genome. few differences nucleotide originated from mutations laboratory cultures and/or mixed sequences. quantification genomic RNA done RT-ddPCR methods, level LoD...
Abstract Scrub typhus is an acute febrile illness caused by the intracellular pathogen Orientia tsutsugamushi . The clinical features include fever, myalgia, lymphadenopathy, and dry mouth. However, no studies have assessed symptom of mouth in patients with scrub typhus. We investigated pattern salivary scintigraphy during state compared it any changes after treatment. Fourteen underwent both pre- post-treatment scintigraphy. Imaging analysis was conducted using radioactivity oral cavity,...