Tomoka Okamura

ORCID: 0000-0002-0153-7008
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Neonatal Health and Biochemistry
  • Congenital Diaphragmatic Hernia Studies
  • Prenatal Screening and Diagnostics
  • Maternal Mental Health During Pregnancy and Postpartum
  • Parvovirus B19 Infection Studies
  • Neuroscience of respiration and sleep
  • Prenatal Substance Exposure Effects
  • Heme Oxygenase-1 and Carbon Monoxide
  • Assisted Reproductive Technology and Twin Pregnancy
  • Thyroid and Parathyroid Surgery
  • Esophageal and GI Pathology
  • Myasthenia Gravis and Thymoma
  • Cardiovascular and Diving-Related Complications
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Pharmaceutical studies and practices
  • Infant Development and Preterm Care
  • Liver Disease and Transplantation
  • Hemoglobinopathies and Related Disorders
  • Child Nutrition and Water Access
  • Acute Myeloid Leukemia Research
  • Iron Metabolism and Disorders
  • Infant Nutrition and Health
  • Birth, Development, and Health

Okayama University
2017-2024

Tokyo Women's Medical University
2015-2021

The aim of this study was to clarify the effects gestational age and birth weight on outcomes infants. Medical records 36 infants with trisomy 18 admitted Tokyo Women's University Hospital from 1991 2012 were reviewed retrospectively. We compared clinical characteristics between term (n = 15) preterm 21). There one very‐low‐birth‐weight (VLBW) infant (5%) 12 VLBW (80%). Although there no significant differences in provided management two groups, none achieved survival discharge. On other...

10.1002/ajmg.a.37246 article EN cc-by-nc-nd American Journal of Medical Genetics Part A 2015-08-26

We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks 5 days pregnancy, underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in subsequent weeks. The premature baby positive MuSK antibodies was successfully delivered, but male required temporary artificial ventilation. However, his condition...

10.2169/internalmedicine.8636-16 article EN Internal Medicine 2017-01-01

BackgroundNitric oxide (NO) may be related to the pathogenesis of several morbidities in extremely preterm infants, including late-onset adrenal insufficiency. However, eosinophilia is observed under pathological conditions with Therefore, this study explored postnatal changes NO levels and eosinophil counts infants without morbidities.MethodsNineteen a median gestational age 27.0 weeks birth weight 888 g were enrolled study. Serum nitrogen oxides (NOx) peripheral blood measured at every 2...

10.1016/j.pedneo.2023.08.006 article EN cc-by-nc-nd Pediatrics & Neonatology 2023-10-21

Most cases of transient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) resolve spontaneously; however, DS-TAM hydrops fetalis (HF) show poor clinical outcomes. We report three infants and HF who were treated exchange transfusion (ET) followed by low-dose cytarabine (LD-CA). All them survived without developing liver failure, acute leukemia, or other serious adverse events. Our results suggest that this combination treatment ET LD-CA would be safe, tolerable effective as an...

10.18926/amo/56655 article EN PubMed 2019-04-01

<b><i>Introduction:</i></b> This study aimed to develop models for predicting total serum bilirubin by correcting errors of transcutaneous using machine learning based on neonatal biomarkers that could affect spectrophotometric measurements tissue bilirubin. <b><i>Methods:</i></b> retrospective included infants born at our hospital (≥36 weeks old, ≥2,000 g) between January 2020 and December 2022. Infants without a phototherapy history were...

10.1159/000535970 article EN Neonatology 2024-04-29

Abstract We present the case of a girl with complete tetraploidy who has survived to her age 4 years and 1 month. Infants have been described limited lifespan owing complications. report characteristics, medical history, development.

10.1002/ajmg.a.63717 article EN cc-by American Journal of Medical Genetics Part A 2024-06-23

We examined the effects of being born small for gestational age (SGA) on risk hospitalised common diseases during childhood.This Japanese nationwide, population-based longitudinal survey followed babies before 42 weeks gestation from 10 to 17 January and July 2001, using data Government's Longitudinal Survey Babies in 21st Century. Our study 41 268 children until 5.5 years age: 39 107 full term (8.7% SGA) 2161 preterm (15.5% SGA). evaluated relationship between SGA status hospitalisation...

10.1111/apa.14507 article EN Acta Paediatrica 2018-07-20

Abstract Background No relationship has been reported between nonopiate neonatal abstinence syndrome (NAS) and anthropometric indices, including head circumference (HC). The purpose of this study was to determine the maternal nonopioid drug use HC at birth in neonates with NAS. Methods This retrospective observational included born January 1, 2010 March 31, 2019, whose mothers had taking antipsychotic, antidepressant, sedative, or anticonvulsant medications. outcome measures were HCs NAS...

10.1017/s1092852920001522 article EN CNS Spectrums 2020-07-01

Neonatal abstinence syndrome (NAS) induced by opiate use is common worldwide. Psychiatric drugs are a more cause of NAS in Japan but infants mothers taking psychiatric medications do not always develop NAS. The purpose this study was to practical model for predicting the onset nonopiate-induced NAS, using variables available at birth.In diagnostic study, prediction models were developed multivariable logistic regression with retrospective data collected our hospital between 2010 and 2019....

10.1111/ped.15435 article EN Pediatrics International 2022-12-07

Histidine-rich glycoprotein (HRG) has been reported to inhibit signaling leading the release of high mobility group box 1 protein, a damage-associated molecular pattern. The present study aimed determine longitudinal change in HRG levels extremely preterm infants and assess whether complications such as bronchopulmonary dysplasia (BPD) were associated with differences levels. In this multicenter, prospective, observational study, we measured serum every 2 weeks from birth 8 age. Serum was...

10.3390/biomedicines11010212 article EN cc-by Biomedicines 2023-01-14

Background To evaluate the 8- and 11-year follow up outcomes on basis of various parameters including remission rate, pulmonary function, FeNO, IgE level RAST in children with asthma who developed recurrent attacks started early intervention anti-inflammatory treatment for active induction before 2 years age.

10.1097/01.wox.0000411653.10313.2c article EN cc-by-nc-nd World Allergy Organization Journal 2012-02-01

Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by authors. Any queries (other than missing content) should be directed to corresponding author article.

10.1111/ped.13908 article EN Pediatrics International 2019-07-01

Late-onset circulatory collapse (LCC) in preterm infants is presumably caused by relative adrenal insufficiency. Because eosinophilia known to be associated with insufficiency, we attempted clarify the relation-ship between and LCC infants. We divided cases of (born at < 28 weeks' gestation) admitted our neonatal intensive care unit 2008-2010 into 2 groups: those diagnosed that received glucocorticoids (LCC group), who did not receive (control group). compared eosinophil counts groups before...

10.18926/amo/62403 article EN PubMed 2021-08-01
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