A5082082778- Laser-Ablation Synthesis of Nanoparticles
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- MicroRNA in disease regulation
- Carbon and Quantum Dots Applications
- Graphene and Nanomaterials Applications
- Advanced Nanomaterials in Catalysis
- Autophagy in Disease and Therapy
- Advanced Glycation End Products research
- Redox biology and oxidative stress
- Nonlinear Partial Differential Equations
- Hippo pathway signaling and YAP/TAZ
- Liver Disease Diagnosis and Treatment
- Diamond and Carbon-based Materials Research
- S100 Proteins and Annexins
- Peroxisome Proliferator-Activated Receptors
- Quantum Dots Synthesis And Properties
- Fern and Epiphyte Biology
- Developmental Biology and Gene Regulation
- Spectral Theory in Mathematical Physics
- Nanoparticles: synthesis and applications
- Analytical Chemistry and Chromatography
- Medicinal Plant Pharmacodynamics Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Metabolomics and Mass Spectrometry Studies
Guangdong Pharmaceutical University
2019-2023
Puer University
2022
Second Affiliated Hospital of Jilin University
2021
Guangzhou Medical University
2018-2020
Stomatology Hospital
2020
Novilytic (United States)
2017
Wuhan University
2010-2017
Purdue University West Lafayette
2013
Abstract Monodispersed, readily‐grafted, and biocompatible surface‐enhanced Raman spectroscopic (SERS) tagging materials are developed; they composed of bimetallic Au@Ag nanoparticles (NPs) for optical enhancement, a reporter molecule signature, carbon shell protection bioconjugation. A controllable convenient hydrothermal synthetic route is presented to synthesize the layer‐by‐layer triplex Au–Ag–C core–shell NPs, which can incorporate Raman‐active label 4‐mercapto benzoic acid (4‐MBA). The...
Background: Understanding the biocompatibility and biointeractions of nano-carbon quantum dots (nano-CQDs) in vitro vivo is important for assessing their potential risk to human health. In previous research, physical properties CQDs synthesized by laser ablation liquid (LAL) method were analyzed detail; however, possible bioapplications not considered. Materials Methods: prepared LAL characterized atomic force microscopy, fluorescence lifetime, absorption spectrum, Fourier-transform infrared...
Hepatitis C virus (HCV) infection of the liver is a global health problem and major risk factor for development hepatocellular carcinoma (HCC). Sensitive methods are needed improved earlier detection HCC, which would provide better therapy options. Metabolic profiling high-risk population (HCV patients) those with HCC provides insights into process carcinogenesis possible biomarkers cancer detection. Seventy-three blood metabolites were quantitatively profiled in (n = 30) cirrhotic HCV 22)...
Vascular smooth muscle cells (VSMCs) excessive migration, a basic change of pathological intimal thickening, can lead to serious cardiovascular diseases such as atherosclerosis, myocardial infarction, and stroke. Ligustilide (LIG), the main active ingredient angelica volatile oil, has been demonstrated exert protective effects on cerebrovascular, circulatory system, immune function. However, whether it protects against thickening VSMCs migration its underlying mechanism remains largely...
The fabrication of inorganic fullerene-like nanoparticles (IFNPs) is an attractive idea due to their unique structures and various potential applications. To date, IFNPs have been made from numerous compounds with layered two-dimensional structures, based on synthetic methods. Here we demonstrated for the first time that molybdenum selenide (MoSe2 IFNPs) can be synthesized by laser ablating a target in 30 vol % ethanol/water mixture at ambient temperature pressure. formation mechanism was...
Atherosclerosis (AS) is a common chronic vascular inflammatory disease and one of the main causes cardiovascular/cerebrovascular diseases (CVDs). Autophagy-related genes (ARGs) play crucial part in pathophysiological processes AS. However, expression profile ARGs has rarely been adopted to explore relationship between autophagy Therefore, using AS may provide new insights for treatment CVDs. The differentially expressed GSE57691 dataset were obtained from Human Autophagy Database (HADb) Gene...
Bacteria communities associated with plants have been given increasing consideration because they are arguably beneficial to their host plants. To understand the ecological and evolutionary impact of these mutualistic associations, it is important explore vast unknown territory bacterial genomic diversity functional contributions major branches tree-of-life. Arguably, this aim can be achieved by profiling applying high throughput sequencing approaches, besides establishing model plant...
To explore the effects of β-sitosterol on VSMC proliferation.A7r5 cells were pretreated with 2 µM angiotensin II (Ang II) for 24 hr to establish an excessive proliferation model, followed by treatment hr. Cells divided into five groups: control, Ang II, and + (2, 4, 8 µM). CCK-8 assay, flow cytometry, Ad-mCherry-GFP-LC3B assay analyzed cell proliferation, cycle, apoptosis, autophagic flux. Additionally, expression proteins was detected western blotting.β-Sitosterol effectively inhibited...
Rare-earth-doped gadolinium-oxide (Gd2O3) nanoparticles (NPs) are increasingly used for magnetic resonance imaging (MRI) and optical (OI). However, to date, the poor data of in vivo hazard assessment has been one obstacle its clinical deployment, especially relative immunotoxicity vivo. In this paper, we synthesized Ho3+-doped Gd2O3 NPs (HoNPs) MRI OI by laser ablation liquid. To best our knowledge, present here most extensive biocompatibility vitro (cell viability apoptosis) (the level...
We for the first time reported that tantalum carbide nanoparticles (TCNPs) synthesized by a one-step laser ablation method are suitable probes CT imaging.