A5102021092- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Tribology and Wear Analysis
- Laser-Ablation Synthesis of Nanoparticles
- Bone Tissue Engineering Materials
- Fiber-reinforced polymer composites
- Aluminum Alloys Composites Properties
- Nanoparticles: synthesis and applications
- biodegradable polymer synthesis and properties
- Nanoplatforms for cancer theranostics
- Advancements in Transdermal Drug Delivery
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
- Additive Manufacturing and 3D Printing Technologies
- Dental Implant Techniques and Outcomes
- MXene and MAX Phase Materials
- Additive Manufacturing Materials and Processes
- Extracellular vesicles in disease
- Conducting polymers and applications
- Carbon and Quantum Dots Applications
- Advanced Sensor and Energy Harvesting Materials
- Polymer Nanocomposites and Properties
- Synthesis and properties of polymers
- Gold and Silver Nanoparticles Synthesis and Applications
- Ultrasound and Cavitation Phenomena
Guangzhou Medical University
2014-2024
China Resources (China)
2024
University of Science and Technology Beijing
2021
Stomatology Hospital
2020
Donghua University
2019
Chinese Academy of Sciences
2009
Deutsch Amerikanisches Institut Saarland
2005
CAE (Canada)
2004
Georgia Institute of Technology
1997-2003
Background: Understanding the biocompatibility and biointeractions of nano-carbon quantum dots (nano-CQDs) in vitro vivo is important for assessing their potential risk to human health. In previous research, physical properties CQDs synthesized by laser ablation liquid (LAL) method were analyzed detail; however, possible bioapplications not considered. Materials Methods: prepared LAL characterized atomic force microscopy, fluorescence lifetime, absorption spectrum, Fourier-transform infrared...
Abstract Cancer stem cells (CSCs) are responsible for the melanoma recurrence, progression, and ineffective therapy. Despite striking anti‐CSCs results in immunotherapy with anti‐programmed death‐1 antibodies (aPD‐1), therapeutic efficacy is restricted by evolution of immune evasion CSCs. Here, a wearable silk‐based microneedle device (SMND) integrating synergistic immunity hydrogen therapy developed. The mainly consists double‐layered MN patch (DLMNP), which employs aPD‐1 loaded silk...
Antibiotic-resistant bacterial strains have been continuously increasing and becoming a supreme threat to public health globally. The nanoparticle-based photothermal treatment has emerged as powerful tool combat toxic bacteria. Photothermal agents (PTAs) with cost-effective high conversion efficiency are highly desirable. Herein, we unite the green process for delamination of V2AlC produce yield mass two-dimensional (2D) V2C nanosheets (NSs) by using algae extracts demonstrate their...
Micro-pore structures are an essential factor for the electrical properties of porous rock. Theoretical conductivity models considering pore structure can highly improve accuracy reservoir estimation. In this study, a characterization method based on multi-fractal theory using capillary pressure is developed. Next, theoretical equation derived new method. Furthermore, distinct interrelationship between fractal dimensions curves (Dv) and resistivity index (Dt Dr) obtained. The experimental...
Accurately predicting the water production rate of multiple-phase fluid flows through porous rock is important for many engineering and geological applications. Taking into account irreducible capillary tortuosity, equivalent element model from previous studies has been improved. Based on improved model, this study proposes a relationship between in two-phase systems resistivity index. The verified using samples, result shows that calculated by new closely matches experimental values,...
Abstract As the most widely used metal material in civil aerospace, aluminum alloy additive manufacturing has great potential for performance and application. Due to particularity of processes, defects such as cracks, pores, inclusions are prone occur during process, which can affect fatigue materials. This paper takes SLM Al-Mg-Sc-Zr high-strength powder research object compares it with 2024-T3 sheet benchmark, its is studied based on CFQ analysis method engineering system. The results show...
Abstract Additive manufacturing parts are widely used in industries such as aerospace, medical, and automotive due to their unique forming methods, which have the advantages of high material utilization, fast speed, ability form complex parts. However, its process characteristics can easily lead occurrence internal external defects, affect fatigue performance metal materials. With continuous improvement comprehensive requirements strength, wear resistance, corrosion resistance aerospace...
As a minimally invasive drug delivery platform, microneedles (MNs) overcome many drawbacks of the conventional transdermal systems, therefore are favorable in biomedical applications. Microneedles with combined burst and sustained release profile maintained therapeutic molecular bioactivity could further broaden its applications as therapeutics. Here, we developed double-network (DN MNs) based on gelatin methacrylate acellular neural matrix (GelMA-ACNM). ACNM function an early matrix,...
Abstract: Poor toxicity characterization is one obstacle to the clinical deployment of Gd 2 O 3 @SiO core-shell nanoparticles (Gd-NPs) for use as magnetic resonance (MR) imaging contrast agents. To date, there no systematic data available Gd-NPs prepared by laser ablation in liquid. In this article, we systematically studied Gd-NPs' cytotoxicity, apoptosis vitro, immunotoxicity, blood circulation half-life, biodistribution and excretion vivo, well pharmacodynamics. The results show toxicity,...
The coral, whose main composition is aragonite‐type calcium carbonate, has been widely used as bone substitute in clinic. However, the study on carbonate bioceramic not largely reported due to difficulty sintering which liable evidently decompose at low temperature. In this study, a novel composite ceramic was fabricated by fast A degradable, biocompatible phosphate‐based glass ( PG ) grew liquid temperature added agent process. schedule explored thermal analysis. phase composition,...
Cell alignment is widely found in various tissues and organs vivo, thus engineering of cell a significant issue tissue engineering. Near-field melt electrospinning (NMES) an emerging technique to produce polymer microfibers, which has been increasingly used prepare scaffold; however, the effect NMES micro-pattern on orientation guidance such as not investigated systematically yet. In this study, poly(ε-caprolactone) (PCL) micro-line array was fabricated by for studies. Different from most...
Photodynamic Therapy (PDT) is a promising alternative treatment for malignancies based on photochemical reaction induced by Photosensitizers (PS) under light irradiation. Recent studies show that PDT caused the abundant release of exosomes from tumor tissues. It well-known as carriers play an important role in cell-cell communication through transporting many kinds bioactive molecules (e.g. lipids, proteins, mRNA, miRNA and lncRNA). Therefore, to explore photodynamic anticancer therapy has...
Poly (lactic) acid (PLA)/poly (caprolactone) (PCL) blends nanofibers, with mean diameter about 600nm, were prepared by electrospinning. This research focused on the morphological and thermal properties of nanofibers made from PLA/PCL bends different PCL content. The results showed that addition could improve morphology nanofibers. film blend fiber at ratio 80:20 is characterized smoothest surface highest orientation. distribution fibers wider than pure PLA. glass-transition temperature PLA...
Abstract The in vivo toxicity of Gd 2 O 3 :Eu 3+ nanoparticles (NPs) used as dual‐modal nanoprobes for molecular imaging has not been studied, and the corresponding mechanism immunotoxicity remains unknown. In this study, we investigated cytotoxicity, vitro apoptosis, NPs. NPs showed little to BALB/c mice. We explored possible role phosphoinositide 3‐kinase (PI3K) signaling pathway found that reactive oxygen species could act secondary messengers cellular signaling, inhibiting PI3K...