A5046897869- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pluripotent Stem Cells Research
- Neuroscience and Neural Engineering
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Additive Manufacturing and 3D Printing Technologies
- CRISPR and Genetic Engineering
- Nanoparticle-Based Drug Delivery
- Advanced Sensor and Energy Harvesting Materials
- Microfluidic and Capillary Electrophoresis Applications
- Liver physiology and pathology
- Polymer Surface Interaction Studies
- Microfluidic and Bio-sensing Technologies
- Cell Image Analysis Techniques
- Conducting polymers and applications
Brigham and Women's Hospital
2014-2019
Harvard University
2014-2019
Harvard–MIT Division of Health Sciences and Technology
2014-2019
Massachusetts Institute of Technology
2014-2019
The University of Queensland
2019
Innovation Research Center
2015-2016
University of Kansas
2015-2016
Bioengineering Center
2015
SASTRA University
2013-2014
Vascularization remains a critical challenge in tissue engineering. The development of vascular networks within densely populated and metabolically functional tissues facilitate transport nutrients removal waste products, thus preserving cellular viability over long period time. Despite tremendous progress fabricating complex constructs the past few years, approaches for controlled vascularization hydrogel based engineered have remained limited. Here, we report three dimensional (3D)...
A novel bioink and a dispensing technique for 3D tissue-engineering applications are presented. The incorporates coaxial extrusion needle using low-viscosity cell-laden to produce highly defined biostructures. system is then coupled microfluidic device control the arrangement deposition, demonstrating versatility of bioprinting technique. This cell-responsive promotes cell migration alignment within each fiber organizing encapsulated cells. As service our authors readers, this journal...
Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been shown to enhance tissue functionality. Bioprinting can be used precisely position cells and cell-laden materials generate architecture. Therefore, it represents an exciting alternative for organ fabrication. Despite the rapid progress in field, development printing processes that fabricate macroscale constructs from ECM-derived hydrogels remained a challenge. Here we report strategy bioprinting...
The inadequacy of animal models in correctly predicting drug and biothreat agent toxicity humans has resulted a pressing need for vitro that can recreate the vivo scenario. One most important organs assessment is liver. Here, we report development liver-on-a-chip platform long-term culture three-dimensional (3D) human HepG2/C3A spheroids assessment. bioreactor design allowed situ monitoring environment by enabling direct access to hepatic construct during experiment without compromising...
Biomaterials currently used in cardiac tissue engineering have certain limitations, such as lack of electrical conductivity and appropriate mechanical properties, which are two parameters playing a key role regulating cell behavior. Here, the myocardial constructs engineered based on reduced graphene oxide (rGO)-incorporated gelatin methacryloyl (GelMA) hybrid hydrogels. The incorporation rGO into GelMA matrix significantly enhances properties material. Moreover, cells cultured composite...
The development of electrically conductive carbon nanotube-based inks is reported. Using these inks, 2D and 3D structures are printed on various flexible substrates such as paper, hydrogels, elastomers. patterns have mechanical electrical properties that make them beneficial for biological applications. As a service to our authors readers, this journal provides supporting information supplied by the authors. Such materials peer reviewed may be re-organized online delivery, but not...
We report the development of a nanoclay-rich bioactive hydrogel for bone regeneration therapy applications.
Myocardial microenvironment plays a decisive role in guiding the function and fate of cardiomyocytes, engineering this extracellular niche holds great promise for cardiac tissue regeneration. Platforms utilizing hybrid hydrogels containing various types conductive nanoparticles have been critical tool constructing engineered tissues with outstanding mechanical integrity improved electrophysiological properties. However, there has no attempt to directly compare efficacy these decipher...
A miniature microscope was designed and fabricated with built-in fluorescence capability for biomedical applications.
Host body response to a foreign medical device plays critical role in defining its fate post implantation.
Abstract Google Glass is a recently designed wearable device capable of displaying information in smartphone-like hands-free format by wireless communication. The also provides convenient control over remote devices, primarily enabled voice recognition commands. These unique features the make it useful for medical and biomedical applications where experiences are strongly preferred. Here, we report first time, an integral set hardware, firmware, software, Glassware that transmission sensor...
Event Abstract Back to Gelatin-based nanocomposite hydrogel as a platform for stem cell tissue engineering Ryan Maloney1, 2, Vijayan Manoharan2, Flavia Castanho2, Settimio Pacelli2 and Arghya Paul1, 2 1 University of Kansas, Bioengineering Graduate Program, United States Chemical Petroleum Engineering, Introduction: Bioactive hydrogels show great promise in clinical applications. Collagen-based hydrogels, such gelatin methacrylate (GelMA), contain amino acid sequences that mimic portions...