A5056987315- Retinal Diseases and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Retinal Development and Disorders
- Immune cells in cancer
- High Altitude and Hypoxia
- Thermal Regulation in Medicine
- Retinopathy of Prematurity Studies
- Neonatal and fetal brain pathology
- Metabolomics and Mass Spectrometry Studies
- Retinal Imaging and Analysis
- Heart Rate Variability and Autonomic Control
Qinghai Provincial Peoples Hospital
2024
Qinghai University
2024
Shanghai Jiao Tong University
2022-2024
Shanghai First People's Hospital
2022-2024
Shanghai Eye Disease Prevention & Treatment Center
2022-2024
Diabetic retinopathy (DR) is the leading cause of blindness among working-age population. Although controlling blood glucose levels effectively reduces incidence and development DR to less than 50%, there are currently no diagnostic biomarkers or effective treatments for in glucose-well-controlled diabetic patients (GW-DR). In this study, we established a prospective GW-DR cohort by strictly adhering glycemic control guidelines maintaining regular retinal examinations over median 2-year...
Diabetic retinopathy (DR) is the leading cause of visual impairment and blindness among working-age population. Microglia, resident immune cells in retina, are recognized as crucial drivers DR process. Microglia activation a tightly regulated immunometabolic In early stages DR, M1 phenotype commonly shifts from oxidative phosphorylation to aerobic glycolysis for energy production. Emerging evidence suggests that microglia not only engage specific metabolic pathways but also rearrange their...
Abstract Background To investigate changes in pulmonary artery pressure (PAP), blood indices, and myocardial microcirculation rats returning from high altitude (HA) to moderate (MA). Methods Forty 4-week-old male Sprague-Dawley were randomly divided into four groups with ten each group. One group was transported the MA area (MA-group), other three HA (HA-group-A, HA-group-B, HA-group-C). After 28 weeks of age, for 0 days, 10 20 respectively. PAP, routine tests, computed tomography perfusion...