Chao Zhang

ORCID: 0000-0002-0193-9728
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About
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Research Areas
  • Reproductive System and Pregnancy
  • Synthesis and Reactions of Organic Compounds
  • Phytochemistry and Bioactive Compounds
  • Pancreatic function and diabetes
  • Medicinal Plant Pharmacodynamics Research
  • CAR-T cell therapy research
  • Receptor Mechanisms and Signaling
  • Immune Cell Function and Interaction
  • Cancer-related molecular mechanisms research
  • Immunotherapy and Immune Responses
  • Ion channel regulation and function
  • Toxin Mechanisms and Immunotoxins
  • Electrospun Nanofibers in Biomedical Applications
  • Ovarian cancer diagnosis and treatment
  • Bioactive Compounds and Antitumor Agents
  • Neuropeptides and Animal Physiology
  • Ultrasound and Hyperthermia Applications
  • Virus-based gene therapy research

Fourth Hospital of Hebei Medical University
2009-2021

Second Affiliated Hospital of Zhejiang University
2021

Hebei Medical University
2009-2021

Abstract Ultrasound‐targeted microbubble destruction (UTMD) mediates gene transfection with high biosafety and thus has been promising toward treatment of type 1 diabetes. However, the potential application UTMD in 2 diabetes (T2D) is still limited, due to lack systematic design dynamic monitoring. Herein, an efficient delivery system constructed by plasmid deoxyribonucleic acid (DNA) encoding glucagon‐like peptide (GLP‐1) ultrasound‐induced microbubbles, T2D macaque. The as designed...

10.1002/smll.202008177 article EN Small 2021-06-29

Most esophageal motility studies are based on animals. It is necessary to explore smooth muscle in the human esophagus. This study was undertaken feasibility of vitro culture cells (SMCs) from esophagogastric junction (EGJ) and determine changes intracellular calcium (Ca2+ ) fluorescence ([Ca2+ ]i SMCs stimulated by acetylcholine (ACh).Primary EGJ (Clasp, Sling, circular (ECM), longitudinal (ELM)) were obtained enzymatic digestion (ED) explant with tissues (EC-T) 9 upper carcinoma patients....

10.1111/nmo.14252 article EN Neurogastroenterology & Motility 2021-09-16
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