A5067592692- Nanoparticles: synthesis and applications
- Reproductive Health and Contraception
- Trace Elements in Health
- Endometriosis Research and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Heavy Metal Exposure and Toxicity
- Surgical Sutures and Adhesives
- E-commerce and Technology Innovations
- Orthopaedic implants and arthroplasty
- Reproductive System and Pregnancy
Xinxiang Medical University
2018
Huazhong University of Science and Technology
2013-2018
Copper nanoparticle-induced ovarian injury, follicular atresia, apoptosis, and gene expression alterations in female rats Jing Yang,1,* Shifu Hu,1,* Meng Rao,1 Lixia Hu,2 Hui Lei,1 Yanqing Wu,1 Yingying Wang,1 Dandan Ke,1 Wei Xia,1,3 Chang-hong Zhu1,3 1Family Planning Research Institute, Tongji Medical College, Huazhong University of Science Technology, Wuhan, Hubei, 2Department Histology Embryology, Preclinical Medicine Xinxiang University, Henan Province, Xinxiang, 3Reproductive Center,...
The physiologic safety of devices and materials intended for clinical implantation should be evaluated. This study, a logical extension our previous work, aimed to investigate the novel contraceptive device, copper/low-density polyethylene nanocomposite intrauterine device (nano-Cu/LDPE IUD), through studies its potential toxicity after acute subchronic administration in mice rats.For single 50 mL/kg doses nano-Cu/LDPE IUD extracts were administered via intravenous or intraperitoneal...
Devices and materials intended for clinical applications as medical implant devices should be evaluated to determine their biocompatibility in physiological systems. This article presents results from cytotoxicity assay of L929 mouse fibroblasts culture, tests skin irritation, intracutaneous reactivity sensitization, material implantation the novel copper/low-density polyethylene nanocomposite intrauterine device (nano-Cu/LDPE IUD) with potential future utilization. Cytotoxicity test vitro...
A copper/low-density polyethylene nanocomposite (nano-Cu/LDPE), a potential intrauterine device component material, has been developed from our research. logical extension of previous work, this study was conducted to investigate the expression plasminogen activator inhibitor 1 (PAI-1), substance P (SP), and receptor (SP-R) in endometrium Sprague Dawley rats, New Zealand White rabbits, Macaca mulatta implanted with nano-Cu/LDPE composite. The influence composite on morphology also...
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