A5103058585- Acute Myeloid Leukemia Research
- Hormonal and reproductive studies
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Muscle metabolism and nutrition
- Breast Cancer Treatment Studies
- Glioma Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Occupational and environmental lung diseases
- Sports Performance and Training
- Cerebral Venous Sinus Thrombosis
- Cerebrovascular and genetic disorders
- Doping in Sports
- Diabetes Treatment and Management
- Porphyrin Metabolism and Disorders
- Family and Patient Care in Intensive Care Units
- Antibiotics Pharmacokinetics and Efficacy
- Trauma Management and Diagnosis
- Viral Infections and Vectors
- Pleural and Pulmonary Diseases
- Neurological Complications and Syndromes
- Diabetes Management and Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neonatal Health and Biochemistry
Wockhardt (India)
2020
North Shore Medical Center
2012-2017
Salem Hospital
2017
Beth Israel Deaconess Medical Center
2015-2017
Harvard University
2014-2015
Massachusetts General Hospital
2014
Boston Medical Center
2010-2011
Boston University
2010-2011
Testosterone supplementation has been shown to increase muscle mass and strength in healthy older men. The safety efficacy of testosterone treatment men who have limitations mobility not studied.
Testosterone in Older Men with Mobility Limitations Trial determined the effects of testosterone on muscle performance and physical function older men mobility limitation. Trial's Data Safety Monitoring Board recommended enrollment cessation due to increased frequency adverse events arm. The changes were evaluated relation participant's perception change. aged 65 years older, limitation, total 100–350 ng/dL, or free less than 50 pg/mL, randomized placebo 10 g gel daily for 6 months. Primary...
Isolated myeloid sarcoma (MS) is a rare extramedullary presentation of acute leukemia (AML). Little known about MS outcomes due to its rarity. A population-based analysis using the Survival, Epidemiology, and End Results (SEER) database was performed. We identified 345 patients, aged 15 or older, diagnosed with isolated between 1973 2010. Overall survival (OS) calculated compared non-MS AML log-rank test. Survival also evaluated based upon primary site disease presentation. The 3-year rate...
Tumor lysis syndrome (TLS) is an oncologic emergency that caused by massive tumor cell lysis. It commonly associated with hematological cancers like leukemia and lymphoma uncommonly solid nonhematologic tumors as well. However, spontaneous (STLS) without any cytotoxic chemotherapy rarely occurs in tumors. We describe a case of STLS metastatic adenocarcinoma unknown primary review the literature non-hematologic to identify various risk factors for pathogenesis this entity.
West Nile virus (WNV) is still the most common cause of neuroinvasive arboviral disease in USA with a case death 10–30%. We are reporting 61-year-old woman history Crohn's disease, fibromyalgia treated chronic steroid therapy that presented day fever, confusion and lethargy. She had lumbar puncture which was notable for lymphocytosis positive WNV. initially broad-spectrum antibiotics, were subsequently discontinued when diagnosis WNV (WNND) made. A high index suspicion needed to diagnose...
7075 Background: Myeloid sarcoma (MS) is a rare extramedullary presentation of acute myeloid leukemia (AML), which can involve number primary locations. MS exist concurrently with marrow involvement or as an isolated phenomenon. Little known about outcomes in due to its rarity. We performed analysis using the Survival, Epidemiology, and End Results (SEER) database. Methods: Using SEER database, we identified 339 patients, aged ≥ 15 diagnosed between 1973-2010. Overall survival (OS) was...
147 Background: Dual neoadjuvant HER2 directed therapy is offered only in a clinical trial setting and not standard of care, but emerging data suggests targeting multiple mechanisms may be more effective. We conducted comprehensive systematic review meta-analysis to evaluate the impact dual single agent blockade on breast conserving surgery (BCS), pathological complete response (pCR) for estrogen receptor (ER)+ ER- tumors, as well pCR disease-free survival (DFS) overall (OS) HER2+ cancer....
Malignant mesothelioma is an uncommon neoplasm of serosal surfaces, such as the pleura, peritoneum, less frequently pericardium and tunica vaginalis. It usually spreads locally to lungs mediastinum. We describe a case malignant with metastasis heart. The patient presented syncope, chest pain light-headedness. He was found have wide complex ventricular tachycardia (Vtach). cardioverted then noted multiple (more than 20) similar episodes during hospital course. treated antiarrhythmic...
We describe the case of a healthy 23-year-old man who presented to emergency room with 10 h history sharp left lower chest pain occasionally radiating epigastrium. The had started acutely while he was eating dinner at restaurant in New York City and noticed it during swallowing. initially but later became dull. There were intermittent episodes pain, exacerbated by deep inspiration Lying on his right side alleviated pain. He reported no fevers, cough, nausea or vomiting. Initial evaluation...
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e13034 Background: Primary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin’s confined primarily to the system. T-cell PCNSLs comprise less than 4% all and they appear have worse prognosis B cell PCNSLs. The incidence rising due to, in part, better neuroimaging modalities. objective this study was gain more depth understanding clinical presentation disease treatment outcomes that may affect patient survival. Methods: A systematic review literature performed...
e13035 Background: Primary spinal cord glioblastoma (PSCG) is rare, accounting for only 1.5% of all tumors. However, it appears to have an aggressive course and poor prognosis.The objective this study was gain a more in depth understanding the clinical presentation PSCG factors that may affect patient survival. Methods: A systematic literature search conducted within PubMed, covering years from 1936 2013. Search case descriptions PSCG. Inclusion criteria included primary tumor originating...
Introduction: In today's patient and family centered care model, frequent communication with families is paramount in providing excellent especially the Intensive Care Unit (ICU), as patients may not be able to advocate for themselves. The frequency of ICU directly related their experience. To serve this purpose raise physician awareness importance daily communication, our institution implemented a comprehensive MD - project. Methods: A multidisciplinary workgroup consisting residents, staff...
647 Background: While the addition of trastuzumab to neoadjuvant chemotherapy (CTX) is well established for HER2+ BC, use dual agent HER2 blockade in preoperative setting not considered standard care. We conducted a comprehensive systematic review and meta-analysis evaluate impact single on breast conserving surgery (BCS), pathological complete response (pCR) estrogen receptor (ER)+ ER- tumors, pCR disease-free survival (DFS) overall (OS) BC. Methods: Based QUORUM guidelines, MEDLINE...