A5029088325- Cognitive Abilities and Testing
- Functional Brain Connectivity Studies
- Child Development and Digital Technology
- Genetics and Neurodevelopmental Disorders
- Neural and Behavioral Psychology Studies
- Cognitive and developmental aspects of mathematical skills
- Cognitive Science and Mapping
- Birth, Development, and Health
- Diet and metabolism studies
- Early Childhood Education and Development
- Child and Animal Learning Development
- AI in cancer detection
- Media Influence and Politics
- Spatial Cognition and Navigation
- Advanced Causal Inference Techniques
- Evaluation and Performance Assessment
- Health Systems, Economic Evaluations, Quality of Life
- Neuroscience, Education and Cognitive Function
- Traumatic Brain Injury Research
- Impact of Technology on Adolescents
- Gene expression and cancer classification
- Fashion and Cultural Textiles
- Advanced X-ray and CT Imaging
- Climate variability and models
- Pain Management and Placebo Effect
Karolinska Institutet
2019-2024
Radboud University Medical Center
2021-2024
Radboud University Nijmegen
2021-2024
University Medical Center
2024
Southern Connecticut State University
2021-2022
Vrije Universiteit Amsterdam
2022
University of Duisburg-Essen
2022
Liebherr (Germany)
2022
Genetic factors and socioeconomic status (SES) inequalities play a large role in educational attainment, both have been associated with variations brain structure cognition. However, genetics SES are correlated, no prior study has assessed their neural associations independently. Here we used polygenic score for attainment (EduYears-PGS), as well SES, longitudinal of 551 adolescents to tease apart genetic environmental development Subjects received structural MRI scan at ages 14 19. At time...
Abstract Digital media defines modern childhood, but its cognitive effects are unclear and hotly debated. We believe that studies with genetic data could clarify causal claims correct for the typically unaccounted role of predispositions. Here, we estimated impact different types screen time (watching, socializing, or gaming) on children’s intelligence while controlling confounding differences in cognition socioeconomic status. analyzed 9855 children from USA who were part ABCD dataset...
Abstract We estimated the degree to which language used in high-profile medical/public health/epidemiology literature implied causality using linking exposures outcomes and action recommendations; examined disconnects between identified most common phrases; how strongly phrases imply causality. searched for screened 1,170 articles from 18 journals (65 per journal) published 2010–2019. Based on written framing systematic guidance, 3 reviewers rated of abstracts full text exposure/outcome...
Our performance on cognitive tasks fluctuates: the same individual completing task will differ in their response’s moment-to-moment. For decades fluctuations have been implicitly ignored – treated as measurement error with a focus instead aggregates such mean performance. Leveraging dense trial-by-trial data and novel time-series methods we explored variability an intrinsically important phenotype. Across eleven over 7 million trials, found highly reliable interindividual differences every...
Digital media (DM) takes an increasingly large part of children's time, yet the long-term effect on brain development remains unclear. We investigated how individual effects DM use (i.e., using social media, playing video games, or watching television/videos) cortex global cortical surface area), striatum, and cerebellum in children over 4 years, accounting for both socioeconomic status genetic predisposition. used a prospective, multicentre, longitudinal cohort from Adolescent Brain...
Telomere length is increasingly used as a proxy for an aging exposome", index of non-genetic environmental (and behavioral) exposures that individual encounters, leading to differences in rates aging. One the largest associations with telomere schooling, suggestion long-lasting protective effects (additional) education. However, ethical and practical reasons, education cannot generally be randomized, precluding understanding causal effect on health outcomes. Here, we leverage...
On some days we feel like are not performing at our best. However, whether these experiences align with substantive differences in cognitive performance has been studied systematically. We analyse dense time-series data of children’s on nonverbal reasoning (n=449; t=454,913) and visuospatial working memory (n=4150; t=1,048,576) tasks using dynamic structural equation models to describe their pattern instability across trials days. Our model comparison confers domain-specific results,...
Schooling, socioeconomic status (SES), and genetics all impact intelligence. However, it is unclear to what extent their contributions are unique if they interact. Here we used a multi-trait polygenic score for cognition (cogPGS) with quasi-experimental regression discontinuity design isolate how months of schooling relate intelligence in 6567 children (aged 9-11). We found large, independent effects (β ~ 0.15), cogPGS 0.10), SES 0.20) on working memory, crystallized (cIQ), fluid (fIQ)....
The interplay of genetic and environmental factors behind cognitive development has preoccupied multiple fields science sparked heated debates over the decades. Here we tested hypothesis that developmental genes rely heavily on challenges-as opposed to natural maturation. Starting with a polygenic score (cogPGS) previously explained variation in performance adults, estimated its effect 344 children adolescents (mean age 12 years old, ranging from 6 25) who showed changes working memory (WM)...
Abstract Education is related to a wide variety of beneficial health, behavioral, and societal outcomes. However, whether education causes long-term structural changes in the brain remains unclear. A pressing challenge that individuals self-select into continued education, thereby introducing environmental genetic confounders. Fortunately, natural experiments allow us isolate causal impact increased from individual (and societal) characteristics. Here, we exploit policy change UK (the 1972...
Classically, neuropsychological evaluation only estimates an individual's performance at one time point. For example, working memory (WM) capacity is commonly determined in a single test session. However, recent research WM plasticity and variability has suggested over several sessions/days might aid evaluating children. Here, we explored four temporal properties of WM: measured once, as mean three days (multiple-session-baseline performance), 8 weeks, improvement 8-week training program. To...
Our reactions to a stranger can often be influenced by the clothes he wears. In this study male experimenter, whilst posing as market researcher, dressed either smartly or untidily. Style of dress was found have significant influence upon number agreements from both older and younger women answer interviewer's questions. Dress did not men individuals were more clothing than ones. The results are believed implications for many kinds interview settings.
Our performance on cognitive tasks fluctuates: the same individual completing task will differ in their response’s moment-to-moment. For decades fluctuations have been implicitly ignored – treated as measurement error with a focus instead aggregates such mean performance. Leveraging dense trial-by-trial data and novel time-series methods we explored variability an intrinsically important phenotype. Across eleven over 7 million trials, found highly reliable interindividual differences every...
Spatial and mathematical abilities are strongly associated. Here we analyzed data from 17,648 children, aged 6-8 years, who performed 7 weeks of training together with randomly assigned, spatial cognitive tasks demanding more manipulation (mental rotation or tangram), maintenance information (a visuo-spatial working memory task) spatial, non-verbal reasoning. We found that what type children had a significant impact on learning, reasoning being the most effective. This large, community-based...
The objective was to clarify occurrence, phenomenology, and risk factors for novel psychiatric disorder (NPD) in the first 3 months after mild traumatic brain injury (mTBI) orthopedic (OI). Children aged 8-15 years with mTBI (n = 220) OI but no TBI 110) from consecutive admissions an emergency department were followed prospectively at baseline post-injury semi-structured interviews document number of NPDs that developed each participant. Pre-injury child variables (adaptive, cognitive,...
Abstract Genetic factors and socioeconomic (SES) inequalities play a large role in educational attainment, both have been associated with variations brain structure cognition. However, genetics SES are correlated, no prior study has assessed their neural associations independently. Here we used polygenic score for attainment (EduYears-PGS) as well SES, longitudinal of 551 adolescents, to tease apart genetic environmental development Subjects received structural MRI scan at ages 14 19. At...
<title>Abstract</title> <bold>Background</bold> Children’s cognitive performance fluctuates across multiple timescales. However, fluctuations have often been neglected in favour of research into average performance, limiting the unique insights abilities and development that variability may afford. Preliminary evidence suggests greater is associated with increased symptoms neurodevelopmental disorders, differences behavioural neural functioning. The relative dearth empirical work on...
Education is related to a wide variety of beneficial health, behavioral, and societal outcomes. However, whether education causes long-term structural changes in the brain remains unclear. A pressing challenge that individuals self-select into continued education, thereby introducing environmental genetic confounders. Fortunately, natural experiments allow us isolate causal impact increased from individual (and societal) characteristics. Here, we exploit policy change UK (the 1972 ROSLA act)...
Education is related to a wide variety of beneficial health, behavioral, and societal outcomes. However, whether education causes long-term structural changes in the brain remains unclear. A pressing challenge that individuals self-select into continued education, thereby introducing environmental genetic confounders. Fortunately, natural experiments allow us isolate causal impact increased from individual (and societal) characteristics. Here, we exploit policy change UK (the 1972 ROSLA act)...
Abstract Clear data visualization is essential to effectively communicate empirical findings across various research fields. Raincloud plots fill this need by offering a transparent and statistically robust approach visualization. This achieved combining three in an aesthetically pleasing fashion. First, dot plot displays raw with minimal distortion, allowing fast glance at the sample size outlier identification. Next, box key distributional summary statistics such as median interquartile...
Abstract We estimated the degree to which language used in high profile medical/public health/epidemiology literature implied causality using linking exposures outcomes and action recommendations; examined disconnects between identified most common phrases; how strongly phrases imply causality. searched screened for 1,170 articles from 18 high-profile journals (65 per journal) published 2010-2019. Based on written framing systematic guidance, three reviewers rated of abstracts full text...